While considerable efforts and progress in our understanding of the long-term toxicities of surgery, radiation and chemotherapy in children with cancer have been made over the last 5 decades, there continues to be a wide gap in our knowledge of the long-term health impact of most novel targeted and immunotherapy agents. To address this gap, ACCELERATE, a multi-stakeholder collaboration of clinical

Aims: To assess feasibility and acceptability of exercise in clinically referred adolescents with major depression. Methods: Outpatients12 to 17 years with mild to moderate persistent depression participated in a supervised, pulse monitored, 14-week aerobic exercise but without control group. Primary outcome was adherence and secondary was clinician-rated Quick Inventory of Depressive Symptomatolo

III-V MOSFETs provide improved electrostatic control at scaled gate lengths combined with a considerable reduction in gate leakage current. Following the natural transistor evolution, we investigate vertical III-V nanowire MOSFETs and fabricate MOSFETs with gm>3 S/mm integrated on Si substrates. Careful investigations of the dynamic properties show high MSG-value of 14.5 dB at 20 GHz with a small-

The Ottfjället Dyke Swarm (ODS) is a prominent component of the Ediacaran mafic magmatism associated with opening of the Iapetus ocean, and hosted in the Särv Nappe, Middle Allochthon of the Scandinavian Caledonides. A U-Pb baddeleyite age of 596.3 ± 1.5 Ma for a thick, well preserved, plagioclase-phyric dolerite dyke in Härjedalen, Sweden, dates emplacement of the swarm. The age represents a robu

Range expansions can be shaped by sex differences in behaviours and other phenotypic traits affecting dispersal and reproduction. Here, we investigate sex differences in morphology, behaviour and genomic population differentiation along a climate-mediated range expansion in the common bluetail damselfly (Ischnura elegans) in northern Europe. We sampled 65 sites along a 583-km gradient spanning the

Means–ends decoupling, the institutionally induced implementation of ineffective practices, has become increasingly common. Extant theory suggests that means–ends decoupling has real consequences, which makes it unstable and difficult for organizations to sustain. Yet little is known of how, and with what outcomes, firms organize such means–ends decoupling. We examine organizing via multiple quali

Bilismen orsakar en mängd problem i våra städer. Det handlar dels om negativa effekter på människors hälsa på grund av skadliga partikelutsläpp, buller, trafikolyckor och stillasittande, dels om platsen den tar i anspråk vilket leder till trängsel och att värdefull mark tas i besittning av väginfrastruktur och parkeringsplatser. I ett större perspektiv bidrar biltrafiken även till utsläpp av växthTraffic accumulated by cars is responsible for considerable problems in our cities. The problem is partly about the negative effects on human health due to harmful particulate emissions, noise, traffic accidents and sedentary lifestyles, partly about the space it occupies, which leads to congestion, and the fact that valuable land is taken up by road infrastructure and parking lots. In a bigger pe

How global gridded crop models (GGCMs) differ in their simulation of potential yield and reasons for those differences have never been assessed. The GGCM Intercomparison (GGCMI) offers a good framework for this assessment. Here, we built an emulator (called SMM for simple mechanistic model) of GGCMs based on generic and simplified formalism. The SMM equations describe crop phenology by a sum of gr

I denna bok presenteras nya perspektiv på det svenska ståndssamhället. Det görs genom en undersökning av Malmö mellan 1720 och 1780. Ståndssamhället var något mycket mer än bara indelningen i adel, präster, borgare och bönder. Stånd var beroende av att gränser mellan grupper markerades genom olika juridiska rättigheter. Det handlade dock inte bara om juridik. Statusindelningar upprätthölls i befol

Optical and laser diagnostics is a field where optical techniques are developed that offer remote, non-intrusive measurements in order to characterise a system. Imaging is a big part of this field and the versatility it offers makes it a great tool in the hands of researchers and in practical applications. In this thesis, multiple applications of imaging are presented, together with possible data

This article analyzes the use of metaphysics to speak of God within theology. More specifically, the charge of ontotheology levelled against Thomas Aquinas, in particular by Jean-Luc Marion and John Caputo, are being analyzed and criticized, not only with the help of thinkers like John Knasas and W. Norris Clarke, but also Marion himself. Because this article also examines the change of heart that

Title: Attitudes, cognition, and functional disability in individuals with self-harm and psychiatric disorders.Background: Self-harm is common and is associated with stigma and an increased risk for suicide attempts. There is a lack of knowledge about this behaviour, especially in clinical samples. Executive functions might be associated with self-harm, and there is also evidence that adverse chil

AbstractBackground: Areal bone mineral density (aBMD) measured by dual-energy X-ray absorptiometry (DXA) is a surrogate estimate of bone strength. The highest value in life is referred to “peak bone mass” (PBM). In the femoral neck (FN), PBM is reached late in the second decade in life, after which there is an age-related decline in aBMD during adulthood. However, a decrease in aBMD may follow a d

This thesis addresses the main challenges in using III-V nanowireMOSFETs for high-frequency applications by building a III-Vvertical nanowire MOSFET technology library. The initial devicelayout is designed, based on the assessment of the current III-V verticalnanowire MOSFET with state-of-the-art performance. The layout providesan option to scale device dimensions for the purpose of designing vari

Background: The effect of change in hip anatomy on change in gait pattern is not well described in current literature. Therefore, our primary aim was to describe and quantify changes in hip geometry and gait pattern 1 year after total hip arthroplasty (THA) in individuals with hip osteoarthritis. Our secondary aim was to explore the effect of postoperative change in femoral neck anteversion (FNA)

Highly pathogenic emm1 Streptococcus pyogenes strains secrete the multidomain Streptococcal inhibitor of complement (SIC) that binds and inactivates components of the innate immune response. We aimed to determine if naturally occurring or vaccine-induced antibodies to SIC are protective against invasive S. pyogenes infection. Immunisation with full-length SIC protected mice against systemic bacter