C-terminal Modifications and Short Oligopeptide Mimetics of Pancreatic Polypeptides in Y4 Receptor Activation
Pancreatic polypeptide (PP) is a gut-derived hormone of the neuropeptide Y family that regulates appetite, gastrointestinal motility, and energy homeostasis through activation of the neuropeptide Y4 receptor (Y4R). With the rising prevalence of obesity, understanding the molecular pharmacology and structure-function relationships of PP-Y4R interactions is essential for the development of novel ant
