Selective, Green Synthesis of Six-Membered Cyclic Carbonates by Lipase-Catalyzed Chemospecific Transesterification of Diols with Dimethyl Carbonate
A facile and green synthesis of six-membered cyclic carbonates, the potential monomers for isocyanate-free polyurethanes and polycarbonates, was achieved by transesterification of diols with dimethyl carbonate catalyzed by immobilized Candida antarctica lipase B, Novozym (R) 435, followed by thermal cyclization in a solvent-free medium. The difference in the chemospecificity of the lipase for the