PURPOSE: HAMLET is a protein-lipid complex that kills different types of cancer cells. Recently we observed a rapid reduction in human bladder cancer size after intravesical HAMLET treatment. In this study we evaluated the therapeutic effect of HAMLET in the mouse MB49 bladder carcinoma model. MATERIALS AND METHODS: Bladder tumors were established by intravesical injection of MB49 cells into poly

Information and communication are increasingly being conveyed over the Internet. The forms of service and commerce that we are familiar with today will most likely be reduced in scale in the future to be replaced by new electronic solutions. For this reason, it is important that new technology be designed so that as many people as possible can utilize it. Accessibility to a range of services and i

Popular Abstract in Swedish Det här arbetet handlar om simuleringar av porösa material och transportfenomen vid en mesoskopisk längdskala, det vill säga en längdskala större än en enskild atom men mindre än att alla atomer beter sig som en kontinuerlig enhet. De porösa material som har studerats är membran som används i bränsleceller. Masstransport har även studerats i membranet. Värme- och masstrThe topic of this work is simulations of porous materials and transport phenomena at a mesoscopic length scale, i.e., a length scale larger than an individual atom but smaller than the continuum. The porous material studied is a membrane used in fuel cells. Mass transfer has also been studied in the membrane. Heat and mass transfer has been studied in parallel plate channels, first in saturated ch

Under 1988 påbörjades vid Lunds Tekniska Högskola ett forskningsprojekt rörande kalkutfällning på putsade och målade fasader. Här redovisas problemställningar och vissa resultat. Dessutom tas en diskussion upp rörande den produktinformation som ges av materialtillverkarna.

Human C4b-binding protein (C4BP) is a soluble, multiple-subunit inhibitor of complement that circulates in blood. Recently C4BP was shown to bind DNA, reduce DNA release from necrotic cells and limit DNA-mediated complement activation in solution. Herein we employed nuclear magnetic resonance spectroscopy to measure chemical shift perturbations and used them to restrain the computational docking o

General introduction to the poetry and the verse novels by Australian writer Dorothy Porter

EG-kommissionen har sedan 1997 arbetat med att revidera den europeiska konkurrensrätten och anpassa den till ny ekonomisk teori. Moderniseringen har lett till att regelverket förtydligats genom det vertikala gruppundantaget (1999), de horisontella gruppundantagen (2001) och bildistributionsundantaget (2002). En revision av 1996 års teknikförordning ligger i tiden. Även procedurreglerna genomgår ge

BACKGROUND: Laminin alpha2 chain mutations cause congenital muscular dystrophy with dysmyelination neuropathy (MDC1A). Previously, we demonstrated that laminin alpha1 chain ameliorates the disease in mice. Dystroglycan and integrins are major laminin receptors. Unlike laminin alpha2 chain, alpha1 chain binds the receptors by separate domains; laminin globular (LG) domains 4 and LG1-3, respectively