The advancement of disease-modifying treatments (DMTs) for Alzheimer's disease (AD), along with the approval of three amyloid-targeting therapies in the US and several other countries, represents a significant development in the treatment landscape, offering new hope for addressing this once untreatable chronic progressive disease. However, significant challenges persist that could impede the succ

During the evolution of parasites, co-speciation and host-range expansion are thought to play roles in establishing associations with hosts, while sorting events can lead to dissolution of those associations. To address the roles of these processes, we focus on avian haemosporidian parasites infecting hosts of the intensively studied great tit species complex. We estimated the phylogeography of li

In situ catalysis studies typically correlate catalytic function and majority surface structures, but neglect that difficult-to-detect minority structures might govern catalysis. Here we use an oscillating CO:O2 gas composition to drive structural oscillations on a catalytically active Pd(100) surface and collect X-ray photoelectron spectroscopy data at high measurement frequency to demonstrate th

Sustainable Aviation Fuels (SAF) are the most promising strategy for reducing the carbon emissions of aviation in the near term, but their combustion behavior is not well understood compared to conventional fuels. This work investigates how different properties of SAF may lead to different emergent combustion behavior by targeting a small set of very distinct fuels. The investigation is carried ou

This paper theorizes conditions accelerating experiential learning within venture creation programs (VCPs). Traditionally, experiential learning theory views learning as a slow and self-directed process. In contrast, VCPs offer time-compressed, enterprise-oriented training structured around predetermined plans and schedules. Our theorizing shifts the primary focus from cyclical movements (“loops”)

In this chapter, we explore the integration of sustainable entrepreneurship education in the context of circular entrepreneurship ecosystems, highlighting the necessity of shifting from traditional profit-centric models towards ones that emphasize sustainability and circular economy principles. We critique current educational practices for overlooking environmental and ethical considerations and a

Aquifer classification plays a pivotal role in understanding groundwater dynamics and informing sustainable water resource management, especially in regions under significant stress from over-extraction. This study presents a novel remote sensing-based methodology for classifying aquifers represented by monitoring wells within the study area. The approach integrates stress-strain analysis, incorpo

Critical reflection and self-reflection are two interrelated abilities universally perceived as fundamental for teachers’ professional practice. In European policy documents, these are also linked to the goal of building and consolidating education for democracy (Lenz et al., 2021, p. 9). Moreover, in the Swedish Higher Education Ordinance, they are mentioned in the second competence-and-skills ou

Over the last 25 to 30 years, union density has experienced a significant decline in Denmark, Finland, and Sweden, while remaining relatively stable in Norway and completely unchanged in Iceland. In the first three countries, the weakening of Ghent systems (state-subsidised union unemployment funds) stands out as the primary factor contributing to union decline. In Sweden, this trend is further ex

Imminent crises and the much-needed transition to a sustainable society bring knowledge about de-implementation to the fore. Using case studies with inspiration from process tracing, and with tools from Charles Tilly’s theory on Durable inequality, we identify mechanisms that generate inequality and counteract the implementation of recovery – and strength-based practices. Our case studies of sociaImminent crises and the much-needed transition to a sustainable society bring knowledge about de-implementation to the fore. Using case studies with inspiration from process tracing, and with tools from Charles Tilly’s theory on Durable inequality, we identify mechanisms that generate inequality and counteract the implementation of recovery – and strength-based practices. Our case studies of socia

Introduction: Anti–glomerular basement membrane (GBM) disease is caused by pathogenic antibodies usually targeting the noncollagenous domain of the α3 chain of type IV collagen and frequently presents as rapidly progressive glomerulonephritis and diffuse alveolar hemorrhage (DAH). Rapid reduction of these antibodies is imperative for kidney survival and the mainstay of therapy is the combination o