Background and Aims: Population-based data on prescribed opioid use among adults with Crohn's disease (CD) remain limited. Methods: This nationwide register-based study included individuals ≥ 18 years with incident (2008–2019) or prevalent (2008–2021) CD and up to 10 individually matched reference individuals without inflammatory bowel disease. We categorised opioid dispensations as weak (e.g., tr

Negative symptoms in schizophrenia spectrum are associated with minimal treatment responses. The search for effective treatments is potentially hampered by heterogenous study-designs and sample characteristics depending on the intervention category. This PRISMA-compliant systematic review/synthesis aims to describe the literature on negative symptoms interventions for schizophrenia spectrum disord

Laser-induced fluorescence has been a staple technique for in-situ probing of radicals and atomic species for decades. The multi-photon equivalent is prevalent in a large variety of applications, where such excitation schemes enable the study of otherwise elusive species and systems. However, these variants inherently suffer from low signal intensities, impeding the broader use of multi-photon ima

Unhealthy Body Mass Index (BMI) levels at both ends of the weight spectrum remain a public health concern despite widespread interventions. This ongoing problem points to the importance of understanding the factors that shape BMI beyond behavior and lifestyle alone. The present study therefore investigated the genetic influences on BMI and the predictive roles of intelligence and personality in sh

Startskottet i den cirkulära omställningen: så påbörjar företaget sin cirkulära omställning Hur kan företag få konkreta rekommendationer för att ställa om till en cirkulär ekonomi? Vårt digitala verktyg visar vägen genom att kombinera produktens potential med organisationens förutsättningar – något som är avgörande för en cirkulär omställning då både vad vi gör och hur vi arbetar förändras i samspThis master’s thesis aims to support product-centered companies in their transition to a circular economy (CE) by developing a digital self-assessment and decision support tool. Circularity is a complex field that demands collaboration across multiple system levels. Although a wide range of frameworks, regulations and guidelines exist, the transition remains difficult for companies to navigate. Ex

This thesis investigates whether intermediate and advanced Swedish learners of Japanese language can use prosodic cues—particularly pitch-based features such as downstep—to differentiate between structurally ambiguous noun phrases, specifically those having both left branching (LB) and right branching (RB) interpretations, in spoken Japanese in the same way as native speakers. It also examines

Vad kan stoppa oss från att hitta mörk materia med LDMX? När astronomer tittar på de största objekten i vårt universum ser de att stora strukturer, så som som galaxer och galaxkluster, inte rör sig som de förväntar sig. Det visar sig att det finnas en stor mängd extra materia som vi inte kan se. Denna osynliga materia kallar vi ’mörk materia’. Många teorier för vad mörk materia består av har lagtAccording to astronomical observations of galaxies and other large scale dynamics, the universe contains more mass than what is visible. This missing mass is called "dark matter" and have been a subject of study for physicists for decades. The Light Dark Matter eXperiment (LDMX) is a proposed experiment with the purpose to search for dark matter in a low mass range that not many experime

The aviation industry continues today to be one of the main sources of green house gas emission. In order to counteract this trend, certain solutions are being invested in with one of these being the use of electro-based sustainable aviation fuels. Its drop-in ability and potential for reduction in emissions present eSAF as one of the most attractive and viable alternatives to decarbonisation of t

This thesis focuses on designing a new university hospital in Lund, addressing both technical demands and human needs. It explores the question: “How can the new hospital and intensive care unit (ICU) in Lund be designed in a way that fulfills all the technical demands, but also the more immaterial human needs?” Located on Smörlyckan, the design aligns with the competition for the “Nytt Sjukhusomr

The transition to renewable energy is a critical element in global efforts to combat climate change. This study explores the decarbonization pathway for Peru’s energy sector, emphasizing renewable energy integration in the electricity generation sector. Peru's rich renewable resources—hydropower, wind, solar, geothermal and biomass—highlight its potential as a regional leader in sustainable en

Under de senaste åren har den ökande oro för de miljöförödande konsekvenserna av konvent-ionell plast lett till ett ökat intresse för biobaserade och biologiskt nedbrytningsbara plaster. Som förnybara råvaror för dessa plaster har jordbruksbiprodukter framlagts som en lovande källa. Denna studie undersöker olika jordbruksbiprodukter som potentiella råmaterial för biologiskt nedbrytbar plats. DettaIn recent years, concerns about the damaging environmental effects of conventional plastics have surged, by which biobased and biodegradable plastics have been promoted as a favour-able alternative. Agricultural side streams have been proposed as a potential feedstock for extracting components for new compostable polymers. The present study investigates agri-cultural side streams for raw material

The concept of the library has evolved over time, adapting to the changing needs of society and there are various types of libraries, from public institutions to private collections. Today, digitalization is reshaping how we access information and interact with the world, yet libraries and books continue to hold an essential role as spaces for reflection, learning, and community connection. Smal

Levodopa provides effective symptomatic treatment for Parkinson's disease. However, nonmotor symptoms are often insufficiently relieved, and its long-term use is complicated by motor fluctuations and dyskinesia. To clarify mechanisms of levodopa-induced dyskinesia and pharmacological interventions aimed at reducing dyskinetic symptoms, we have here characterized the neurophysiological activity pat

Extremely thinned layers and possible folding make the dating of the deepest sections of ice cores especially challenging. Cosmogenic radionuclides have the potential to provide independent age estimates. The 36Cl/10Be ratio is largely independent of production rate changes that affect individual radionuclides and has an effective half-life of 384 kyr, making it an ideal tool for dating the new 1.

This thesis explores how disaster-affected communities in the Kavre and Bardiya districts of Nepal perceive and experience cash assistance projects. The research was guided by two core questions: (1) What are community members' perceptions and preferences of cash assistance in disaster affected areas in the Kavre and Bardiya districts of Nepal? (2) How could these community perceptions and pre

As global industries face increasing pressure to adopt circular economy principles and comply with sustainability regulations, packaging has emerged as an important strategic driver. This thesis explores the case of a global industrial manufacturer and how it can enhance its packaging innovation capabilities and align with upcoming regulatory frameworks, such as the Corporate Sustainability Re

Grön energi, som vind-, sol- och vattenkraft, spelar en avgörande roll i omställningen från fossila bränslen. Men hur hållbara är dessa energikällor sett till hela livscykeln? Inom vindkraftsindustrin är detta en särskilt viktig fråga. Vindkraftsblad tas vanligtvis ur bruk efter 20–25 års drift, och har historiskt sett främst gått till förbränning eller deponi. Inget av alternativen är hållbara efThe growing accumulation of end-of-life wind turbine blades (WTBs) presents a challenge due to their increased usage around the world and complex composite structure. Mechanical and thermal recycling techniques often fail to completely recover both the matrix and the embedded fibers without significant degradation or environmental burden. In this thesis, solvolysis is investigated as a promising r

The increase in global competitiveness and the advancement of digital technology are compelling organizations to innovate by enhancing their product offerings with digital services. Although this phenomenon known as digital servitization is well researched in larger organizations, there is less investigation on how small and medium enterprises (SMEs) manage this trend, particularly in Sweden. This

Från industriella restprodukter till grönt drivmedel – två vägar mot förnybara bränslen. Bio-olja från skogsrester kräver uppgradering för att kunna behandlas i befintliga oljeraffinaderier. Två innovativa processer visar potential, men tekniska och ekonomiska utmaningar framstår. Att minska beroendet av fossila bränslen är avgörande för att nå klimatmålen. Ett lovande alternativ är att producerThis master’s thesis evaluates the commercial-scale feasibility of two processes that upgrade lignocellulosic bio-oil: dewatering and derivatization upgrading (DDU) and green cooking and cleaning (GCC). Both processes aim to produce upgraded bio-oil suitable for co-processing in existing oil refineries, though they differ significantly in complexity. GCC includes the entire conversion from raw bio

Augmented reality (AR) is increasingly being adopted in fashion retail to enhance customer ex-perience, boost engagement, and reduce uncertainty in online shopping environments. While AR offers both hedonic and utilitarian value, its implementation across large multinational fashion companies remains inconsistent due to financial, technological, and organizational barriers. This study investigates