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Validity of an algorithm to identify cardiovascular deaths from administrative health records: a multi-database population-based cohort study

Published 15 September 2021 Photo: Pixabay / Ben Kerckx A cardiovascular mortality algorithm applied to administrative health records had moderate validity when compared to vital statistics data. Substantial variation existed across study sites representing different geographic locations and two healthcare systems. These variations may reflect different diagnostic coding practices and healthcare u

https://www.lupop.lu.se/article/validity-algorithm-identify-cardiovascular-deaths-administrative-health-records-multi-database - 2025-07-11

Reflection on modern methods: building causal evidence within high-dimensional molecular epidemiological studies of moderate size

Published 16 September 2021 This commentary provides a practical perspective on epidemiological analysis within a single high-dimensional study of moderate size to consider a causal question. Read the paper at https://academic.oup.com/ije/article/50/3/1016/6140018

https://www.lupop.lu.se/article/reflection-modern-methods-building-causal-evidence-within-high-dimensional-molecular-epidemiological - 2025-07-11

Future of surgical registries

Published 16 September 2021 Photo: Pixabay / Sasin Tipchai The value of accurate healthcare data has never been more apparent than during the past year, and there is increasing recognition of the important role surgical registries play in driving improved patient outcomes, patient safety, and academic research. Successful registries need to be responsive and adapt to the rapidly changing clinical

https://www.lupop.lu.se/article/future-surgical-registries - 2025-07-11

Reflection on modern methods: causal inference considerations for heterogeneous disease etiology

Published 17 September 2021 Photo: Pixabay / Gerd Altmann Molecular pathological epidemiology research provides information about pathogenic mechanisms. A common study goal is to evaluate whether the effects of risk factors on disease incidence vary between different disease subtypes. Read the paper at https://academic.oup.com/ije/article/50/3/1030/6114706

https://www.lupop.lu.se/article/reflection-modern-methods-causal-inference-considerations-heterogeneous-disease-etiology - 2025-07-11

Brain in Picture – The winning photo!

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 2 June 2023 Microglial immune cells around the area of a human embryonic stem cell transplant to treat Parkinson’s Disease in a rat brain. In April, the young MultiPark working group organized a photo competition entitled "Brain in Picture". The external jury has had a hard time choosing, but now, they have appoint

https://www.multipark.lu.se/article/brain-picture-winning-photo - 2025-07-11

Exploring the Role of 'Jumping Genes' in X-Linked Dystonia-Parkinsonism

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 27 June 2023 Postdoctoral researcher Vivien Horvath investigates X-Linked Dystonia-Parkinsonism (XDP), a rare neurodegenerative disorder. New research is underway at Lund University, led by Dr. Vivien Horvath, a postdoctoral researcher at Lund Stem Cell Center. Supported by a new grant from the Collaborative Center for

https://www.multipark.lu.se/article/exploring-role-jumping-genes-x-linked-dystonia-parkinsonism - 2025-07-11

Cell replacement therapy for Parkinson's Disease – Ph.D. interview with Fredrik Nilsson

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 5 July 2023 Fredrik Nilsson defended his thesis on 10 May 2023. Fredrik Nilsson defended his Ph.D. thesis on May 10, 2023. For the last four years, he has explored the use of patient-specific cells in cell replacement therapy for Parkinson's disease to identify strategies to safeguard these transplanted cells from dise

https://www.multipark.lu.se/article/cell-replacement-therapy-parkinsons-disease-phd-interview-fredrik-nilsson - 2025-07-11

New Study Reveals Astrocytes' Role in Frontotemporal Dementia

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 15 August 2023 An image of co-cultures with neuronal projections in purple and astrocytes in green. Image credit: Isaac Canals. One of Multipark's associated research groups has published a new study that reveals the role of astrocytes in the development of frontotemporal dementia (FTD). Their findings, now in the jour

https://www.multipark.lu.se/article/new-study-reveals-astrocytes-role-frontotemporal-dementia - 2025-07-11

Summer greetings from MultiPark at the World Parkinson Congress

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 11 July 2023 Angela Cenci Nilsson was one of the panellists in a session discussing disease mechanisms, non-dopaminergic cells involved in PD, and the latest development regarding gene and cell therapy approaches. Summer is the right period for recharging our batteries through vacations and travels. It also seems t

https://www.multipark.lu.se/article/summer-greetings-multipark-world-parkinson-congress - 2025-07-11

Lewy body disease can be detected before symptoms

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 24 August 2023 Illustration of a Lewy body.(Image: istock.com/Marcin Klapczynski) Lewy body disease is the second most common neurodegenerative disease after Alzheimer's disease. A research group from Lund University has now shown that the disease can be detected before symptoms appear, using a spinal fluid test. The s

https://www.multipark.lu.se/article/lewy-body-disease-can-be-detected-symptoms - 2025-07-11

Electrotherapy without surgery

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 4 September 2023 Find out how electrotherapy works without surgery in this video by Roger Olsson. Researchers at Lund and Gothenburg Universities have successfully developed temporary, organic electrodes that can be seamlessly integrated into biological systems. The method, now published in Nature Communications, opens

https://www.multipark.lu.se/article/electrotherapy-without-surgery - 2025-07-11

How psychedelic drugs affect a rat’s brain

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 19 September 2023 Brainwaves, or neural oscillations, are periodic electrical activities that occur when large groups of neurons work together. Researchers now hope that these signals will teach us more about hallucinations and psychoses. Photo: Pär Halje Researchers at Lund University have developed a technique for simultaneo

https://www.multipark.lu.se/article/how-psychedelic-drugs-affect-rats-brain - 2025-07-11

New study: Parents' metabolic traits can affect the child's health over time

Published 8 April 2025 A human inherits genes from both parents and the genes control what traits a human should have. The researchers behind a new study have studied how metabolic traits are passed on from mothers and fathers to children. Photograph: Kennet Ruona New research at Lund University shows that the biological parents’ genes affect the child's insulin function and capacity to regulate b

https://www.medicine.lu.se/article/new-study-parents-metabolic-traits-can-affect-childs-health-over-time - 2025-07-11

Fine-tuning neural circuits to heal the brain – Segerfalk lecturer Andres Lozano on next-gen neurosurgery

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 10 April 2025 In a world facing rising mental health challenges, neurodegenerative diseases and the limits of current treatments, Andres Lozano’s work points to a future where sound, light and a code may become some of medicine’s most powerful tools. LONGREAD. He treats tremor with sound waves, is preparing to help paralyzed p

https://www.medicine.lu.se/article/fine-tuning-neural-circuits-heal-brain-segerfalk-lecturer-andres-lozano-next-gen-neurosurgery - 2025-07-11

More opportunities to test for Alzheimer’s using new analytical method

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 10 April 2025 “Even with the simpler method of analysis, the blood test gives highly accurate results for Alzheimer’s disease pathology,” says Sebastian Palmqvist, associate professor and senior lecturer in neurology at Lund University. Photo: iStock A simpler method of analysing blood samples for Alzheimer’s disease has been

https://www.medicine.lu.se/article/more-opportunities-test-alzheimers-using-new-analytical-method - 2025-07-11

From molecule to patient – Six promising projects to advance Parkinson's research

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 11 April 2025 April is Parkinson’s Awareness Month. Globally, around 10 million people are affected by Parkinson’s disease—a condition where neurons in brain areas controlling movement gradually degenerate. Photo: Emma Nyberg What role does an inflammatory protein have in disease development? Which neuronal circuit

https://www.medicine.lu.se/article/molecule-patient-six-promising-projects-advance-parkinsons-research - 2025-07-11

Simple medication can save the lives of cardiac patients

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 15 April 2025 “Today’s guidelines recommend stepwise addition of lipid-lowering treatment. But it’s often the case that this escalation takes too long, it’s ineffective and patients are lost to follow-up", says Margrét LeósdóttirPhoto: Åsa Hansdotter Patients suffering from myocardial infarction who receive early add-o

https://www.medicine.lu.se/article/simple-medication-can-save-lives-cardiac-patients - 2025-07-11

Lund Stem Cell Center welcomes a new leadership team

By alexis_bento [dot] luis [at] med [dot] lu [dot] se (Alexis Bento Luis) - published 15 April 2025 The Lund Stem Cell Center at Lund University welcomes the beginning of a new chapter with the appointment of its new leadership team. As of January 1, 2025, Professor Malin Parmar has assumed the role of Director, with Associate Professor Göran Karlsson stepping in as Deputy Director. Together, they

https://www.medicine.lu.se/article/lund-stem-cell-center-welcomes-new-leadership-team - 2025-07-11

Protein changes reveal diseases

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 8 May 2025 Photo: Åsa Hansdotter Researchers at Lund University have developed a new method to determine how the composition of proteins in blood changes in response to disease or organ damage. This could provide a deeper understanding of how diseases affect the body and be used to discover new biomarkers in the blood

https://www.medicine.lu.se/article/protein-changes-reveal-diseases - 2025-07-11