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Human midbrain organoids grown in silk recapitulate midbrain development and support functionally mature dopamine neurons

By marie [dot] jonsson [at] med [dot] lu [dot] se (Marie Jönsson and Alessandro Fiorenzano) - published 17 December 2021 A human midbrain organoid visualised by staining for proteins important during the maturation of dopaminergic neurons. (photo: Alessandro Fiorenzano) In their latest study, published in Nature Communications, the Parmar Lab has established midbrain organoids using silk microfibe

https://www.multipark.lu.se/article/human-midbrain-organoids-grown-silk-recapitulate-midbrain-development-and-support-functionally - 2025-07-27

Ph.D. defence interview - Elin Byman

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 11 January 2022 Elin Byman defends her thesis on the 21st of January 2022. During her thesis project, Elin Byman discovered a role of alpha-amylase in Alzheimer’s disease. January 21, she defends her Ph.D. work supervised by Malin Wennström in the Preclinical memory research group at MultiPark. Here, she tells abou

https://www.multipark.lu.se/article/phd-defence-interview-elin-byman - 2025-07-27

Ph.D. defence interview - Sabine Konings

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 20 January 2022 Sabine Konings defends her thesis on the 27th of January 2022. Sabine Konings’ Ph.D. project sheds light on the role of different genetic variants of apolipoprotein E in early Alzheimer’s disease development. January 27, she defends her thesis. In this interview, she shares the most important findin

https://www.multipark.lu.se/article/phd-defence-interview-sabine-konings - 2025-07-27

eScience for translational movement analysis

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 3 March 2022 The translational project aims at developing aligned methodologies to unravel abnormal movement features in rodent models of Parkinson’s disease and human patients. Illustration: Laura Andreoli MultiPark leads one of the four projects recently selected by Lund University to pursue emerging research top

https://www.multipark.lu.se/article/escience-translational-movement-analysis - 2025-07-27

Working groups – renovation in progress

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 18 February 2022 The PI retreat in January resulted in a groundbreaking decision: MultiPark’s working groups should be replaced by a more dynamic organization including both "special interest groups” and “task force groups”. Here is what will happen. Discussing the MultiPark seven translational working groups was a

https://www.multipark.lu.se/article/working-groups-renovation-progress - 2025-07-27

Ph.D. defence interview - Caroline Haikal

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 1 March 2022 Caroline Haikal defends her thesis on the 11th of March 2022. During her Ph.D. studies, Caroline Haikal has investigated the connections between the gut and the brain in early Parkinson’s disease development. On March 11, she defends her work supervised by Prof. Jia-Yi Li. Here, Caroline tells us about

https://www.multipark.lu.se/article/phd-defence-interview-caroline-haikal - 2025-07-27

World Parkinson's Day – five promising research projects at MultiPark

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 6 April 2022 Photo:Mostphotos Better treatment with the Mange PD tool. A biobank that opens up for discoveries about disease development. Keys to life satisfaction in people with Parkinson’s disease. New insights into toxic protein aggregation. And a more detailed knowledge of abnormal movement patterns with artifi

https://www.multipark.lu.se/article/world-parkinsons-day-five-promising-research-projects-multipark - 2025-07-27

Ph.D. defence interview - Maurits Johansson

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 5 April 2022 Maurits Johansson defends his thesis on the 13th of May 2022. Maurits Johansson investigates neuropsychiatric symptoms in the early stages of Alzheimer’s disease, before cognitive impairments are developed or diagnosis is set. He defends his thesis on May 13. Here, he shares the most important findings

https://www.multipark.lu.se/article/phd-defence-interview-maurits-johansson - 2025-07-27

Young neurobiologists awarded grants for Alzheimer´s and Parkinson´s research

By agata [dot] garpenlind [at] med [dot] lu [dot] se (Agata Garpenlind) - published 20 April 2022 Image: Ben Sweet Two young experimental researchers have been awarded grants from the Anna-Lisa Rosenberg Foundation, the Department of Experimental Medical Science´s own grant for research in the neurobiological field with a clinical collaboration. Congratulations Alessandro Fiorenzano on the Anna-Li

https://www.multipark.lu.se/article/young-neurobiologists-awarded-grants-alzheimers-and-parkinsons-research - 2025-07-27

Ph.D. interview - Oscar Manouchehrian

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 29 April 2022 Oscar Manouchehrian defends his thesis on the 13th of May 2022. Oscar Manouchehrian has explored the roles of exercise and inflammation in neurological disorders. On May 13, he defends his Ph.D. thesis. Here, he shares his insights into academic research and experiences as a Ph.D. student in the Exper

https://www.multipark.lu.se/article/phd-interview-oscar-manouchehrian - 2025-07-27

High quality electrophysiology facilities – MultiPark and Lund SCC join forces

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 5 May 2022 One of the Electrophysiology Core Facilities' rigs in use during an experiment. Photo credit: Johan Persson. This year Lund Stem Cell Center and MultiPark, two strategic research areas based at Lund University, are happy to launch a new joint technical platform in an effort to ensure easy access to high qual

https://www.multipark.lu.se/article/high-quality-electrophysiology-facilities-multipark-and-lund-scc-join-forces - 2025-07-27

New findings may lead the way to future therapeutic approaches for Parkinson’s Disease and similar diseases

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 2 May 2022 Fluorescent microscope image of control MBP-positive oligodendrocytes (in green) co-stained with alpha-synuclein (in red). It is possible to observe neurites positive for alpha-synuclein. Photo Credit: Carla Azevedo. Researchers from Lund University, led by Dr. Laurent Roybon, are working to further define u

https://www.multipark.lu.se/article/new-findings-may-lead-way-future-therapeutic-approaches-parkinsons-disease-and-similar-diseases - 2025-07-27

Brain folds formed during foetal stage could affect onset of dementia

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 11 May 2022 iStock/Jolygon Frontotemporal dementia begins relatively early compared to other forms of dementia. We still know relatively little about what causes the disease, however, new research from Lund University in Sweden shows that the folds in the brain that are formed in the latter stages of pregnancy coul

https://www.multipark.lu.se/article/brain-folds-formed-during-foetal-stage-could-affect-onset-dementia - 2025-07-27

Psychiatric symptoms in Alzheimer´s disease

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 24 May 2022 Photo: Mostphotos In addition to memory problems and other cognitive symptoms, most people with Alzheimer’s disease also suffer from mental health issues. It has long been unclear whether these occur because of tissue changes in the brain, or whether they represent psychological reactions to cognitive s

https://www.multipark.lu.se/article/psychiatric-symptoms-alzheimers-disease - 2025-07-27

The new Cell and Gene Therapy Core Facility is opening

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Bento Luis) - published 10 May 2022 A laboratory expert in action in the Cell and Gene Therapy Core Facility. Earlier this year, Stem Cell Center, in partnership with MultiPark, brought together three core facilities into one - The Cell and Gene Therapy Core Facility - aiming to support advanced science at the highest international leve

https://www.multipark.lu.se/article/new-cell-and-gene-therapy-core-facility-opening - 2025-07-27

Special interest groups open up for more collaboration within MultiPark

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 13 May 2022 Photo: Mostphotos The MultiPark backbone for research interactions is about to be reorganized. Thanks to our members' suggestions, we are now creating 13 special interest groups to address important scientific and technological areas. The process of finding engaged leaders for these groups is about to s

https://www.multipark.lu.se/article/special-interest-groups-open-more-collaboration-within-multipark - 2025-07-27

Huntington’s – a complex brain disease that affects movement, thoughts and feelings

By marianne [dot] loor [at] fsi [dot] lu [dot] se (Marianne Loor) - published 18 May 2022 Åsa Petersén has been researching Huntington’s disease for 25 years and means that a lot can be done to reduce suffering, increase quality of life and make various adaptations for both the patient and their loved ones. Photo: Agata Garpenlind Huntington’s disease is hereditary, genetic and usually begins betw

https://www.multipark.lu.se/article/huntingtons-complex-brain-disease-affects-movement-thoughts-and-feelings - 2025-07-27

"Vaccin mot typ 1 diabetes inom tjugo år"

Publicerad 14 maj 2013 Diabetesstiftelsen i Storbritannien, Diabetes UK, har inlett ett samarbete med livsmedelskedjan Tesco, sedan Tesco beslutat samla in och skänka 10 miljoner pund, motsvarande över 100 miljoner svenska kronor till forskning om typ 1 diabetes. Inom 20 år tror man sig ha ett vaccin inom räckhåll. Dr Alasdair Rankin, forskningschef vid Diabetes UK, säger i ett uttalande att han t

https://www.diabetesportalen.lu.se/artikel/vaccin-mot-typ-1-diabetes-inom-tjugo-ar - 2025-07-27

Ny metod "reparerar" skadade gener

Publicerad 14 maj 2013 På senare år har man upptäckt ett 70-tal genetiska riskvarianter för diabetes, men fortfarande är TCF7L2 - känd som ”diabetesgenen” - den gen som innebär störst risk för att insjukna i typ 2 diabetes. Med hjälp av en ny metod, ”exon skipping”, vill Ola Hansson vid Lunds universitets Diabetescentrum fördjupa kunskapen om TCF7L2 genom att i djurförsök studera nya sätt att förd

https://www.diabetesportalen.lu.se/artikel/ny-metod-reparerar-skadade-gener - 2025-07-27

Inflammationshämmande läkemedel ska förhindra diabetes typ 2

Publicerad 14 maj 2013 Med hjälp av ett enkelt blodprov kan man i dag se att vissa personer i framtiden riskerar att insjukna i typ 2 diabetes. Anders Rosengren, forskare vid Lunds universitets Diabetescentrum och läkare vid Skåne universitetssjukhus i Malmö, håller nu på att studera hur man kan hitta nya behandlingar för personer med en ökad mängd av proteinet SFRP4 i blodet. Tillsammans med dokt

https://www.diabetesportalen.lu.se/artikel/inflammationshammande-lakemedel-ska-forhindra-diabetes-typ-2 - 2025-07-27