Clinical consequences after heart transplantation with reference to osteoporosis, renal function, and immunosuppression. Experiences from Skåne University Hospital in Lund 1988-2019.
Background. Heart transplantation (HT) remains the ultimate final therapy for patients with end-stage heart failure. To prevent rejection of the allograft, life-long immunosuppressive therapy is required. As survival after HT has improved over the past decades, long-term complications, such as chronic kidney disease (CKD) and osteoporosis, are of increasing importance for morbidity and mortality.