Background: Self-selection may compromise cost-effectiveness of screening programs. We hypothesized that nonparticipants have generally higher morbidity and mortality than participants. Methods: A Swedish population-based random sample of 1,986 subjects ages 59 to 61 years was invited to sigmoidoscopy screening and followed up for 9 years by means of multiple record linkages to health and populati

In this paper, we study machine learning techniques and features of electroencephalography activity bursts for predicting outcome in extremely preterm infants. It was previously shown that the distribution of interburst interval durations predicts clinical outcome, but in previous work the information within the bursts has been neglected. In this paper, we perform exploratory analysis of feature e

Heat stress is a major occupational problem in India that can cause adverse health effects and reduce work productivity. This paper explores this problem and its impacts in selected workplaces, including industrial, service, and agricultural sectors in Chennai, India.

We review transverse momentum dependent (TMD) parton distribution functions, their application to topical issues in high-energy physics phenomenology, and their theoretical connections with QCD resummation, evolution and factorization theorems. We illustrate the use of TMDs via examples of multi-scale problems in hadronic collisions. These include transverse momentum q(T) spectra of Higgs and vect

Whether signals mediated via growth factor receptors (GFRs) might influence lineage fate in multipotent progenitors (MPPs) is unclear. We explored this issue in a mouse knockin model of gain-of-function Flt3-ITD mutation because FLT3-ITDs are paradoxically restricted to acute myeloid leukemia even though Flt3 primarily promotes lymphoid development during normal hematopoiesis. When expressed in MP

Stroma properties affect carcinoma physiology and direct malignant cell development. Here we present data showing that alpha(V)beta(3) expressed by stromal cells is involved in the control of interstitial fluid pressure (IFP), extracellular volume (ECV) and collagen scaffold architecture in experimental murine carcinoma. IFP was elevated and ECV lowered in syngeneic CT26 colon and LM3 mammary carc

The theory of symmetric operators has several deep applications to the function theory of certain reproducing kernel Hilbert spaces of analytic functions, as well as to the study of ordinary differential operators in mathematical physics. Examples of simple symmetric operators include multiplication operators on various spaces of analytic functions (model subspaces of Hardy spaces, de Branges-Rovn

Contamination of food with biological toxins aswell as their potential use asweapons of mass destruction has created an urge for rapid and cost effective analytical techniques capable of detecting trace amounts of these toxins. This paper describes the development of a sensitive method for detection of cholera toxin (CT) using a flow-injection capacitive immunosensor based on self-assembled monola

Objective. To investigate the effects of prostate-specific antigen (PSA) testing of men without clinical signs of prostate cancer on the incidence of prostate cancer in Sweden. Material and methods. Information on the cause of diagnosis, tumour characteristics and primary treatment for patients diagnosed with prostate cancer between January 1999 and December 2007 was extracted from the National Pr

Family caregivers in palliative care have a need for knowledge and support from health professionals, resulting in the need for educational and supportive interventions. However, research has mainly focused on the experiences of family caregivers taking part in interventions. To gain an increased understanding of complex interventions, it is necessary to integrate the perspectives of health profes

OBJECTIVE: Products enriched with oat beta-glucan have been shown to reduce postprandial glucose and insulinemic responses. The aim of this study was to evaluate the effect of an extruded muesli product based on oat beta-glucan on the rate of gastric emptying, postprandial blood glucose and satiety in healthy subjects. METHODS: Gastric emptying rate (GER) was measured by standardized real-time ult

The possibility to reduce dependence on fossil fuel resources has led to an increasing interest in the use of bio-fuels. This study builds on earlier work on (aromatic) cyclic oxygenates [1,2], but a far wider window of engine operation has been investigated in this paper. Two parametric variations of engine operation were performed and discussed: (1) non-EGR operation by means of varying the load

Statement of Interest Assessment of visual field damage is the major index of the functional impact of glaucoma with direct relevance to quality of life measures. Visual field change was used as a primary endpoint for progression in the recent glaucoma trials and its measurement is the cornerstone of glaucoma management influencing therapeutic decisions. The objective of this perspective is to pro

During 2007 and 2008 the speed limits 40 och 60 km/h have been tried out in twelve Swedish cities, out of which six have participated in a evaluation in this project, financed by the Swedish National Road Administration. The evaluation has focused on effects from the changes in speed limits on actual speeds, safety, environment and travel times, as well as the attitudes towards the new speed limit

While the advancement in semiconductor technologies enables manufacturing of highly advanced and complex integrated circuits, there is an increasing need of embedded (on-chip) instruments for test, debug, diagnosis, configuration, monitoring, etc. A key challenge is how to access these instruments from chip terminals in a low-cost, non-intrusive, standardized, flexible and scalable manner. The wel

Objectives: The aim of this study was to assess acute health effects on planters caused by planting conifer seedlings treated with two insecticides, with active ingredients imidacloprid and cypermethrin, in comparison with untreated seedlings. Methods: The investigation was a double-blind crossover study, which included a follow-up of 19 planters over a 3-week period. During Week 1, the 19 planter