Isabella Artner’s group Our researchDiabetes results from loss or dysfunction of insulin producing beta cells in the pancreas. Despite insulin injection treatment, diabetic patients suffer from long-term complications, such as blindness and kidney failure. Therefore, a central goal of diabetes research is to regenerate pancreatic beta cells or produce large numbers of functional beta cells for tra

https://www.ludc.lu.se/research/endocrine-cell-differentiation-and-function - 2025-07-25

Eva Degerman’s group Our researchThere is a confirmed relationship between diabetes and dysfunction of the inner ear, our hearing and balance organ, and a large number of reviews and meta-analyses have been published on the subject. However, the mechanisms behind this association are not known. Our ongoing studies indicate that the inner ear is a direct target for insulin action and insulin resist

https://www.ludc.lu.se/research/insulin-signal-transduction - 2025-07-25

Helena Elding Larsson’s group Our researchThe overall purpose of our research is to investigate etiology, prediction, and prevention of pediatric autoimmune diabetes (type 1 diabetes) and other autoimmune diseases. Type 1 diabetes is preceded by an immune-mediated destruction of the pancreatic islet beta cells resulting in loss of insulin production. Genetic factors confer susceptibility and help

https://www.ludc.lu.se/research/pediatric-endocrinology - 2025-07-25

Here we announce projects with innovation potential. Please contact Innovation Office at LUDC for more information. NCE targeting GPCR 321Anna Andersson and her group at Lund University Diabetes center  have identified a lead compound targeting GPCR 123. The new NCE induces insulin secretion and prevents beta cell apoptosis in vitro. The effects have been confirmed in vivo in a rat model, where ta

https://www.ludc.lu.se/innovation-projects - 2025-07-25

Lena Eliasson’s group Our researchOur research aims to understand the impact of deregulated insulin- and glucagon-secretion from pancreatic islet of Langerhans in the aetiology of type 2 diabetes. We also have an interest in islet cell function in more rare diabetes types, such as cystic fibrosis-related diabetes (CFRD) and glucocorticoid-induced diabetes.The main focus of our research is to inves

https://www.ludc.lu.se/research/diabetes-islet-cell-exocytosis - 2025-07-25

LUDC is a consortium of research groups at Lund University headed by Leif Groop dedicated to unravelling the pathogenesis and treatment of diabetes mellitus. LUDC started July 1st 2006 when selected for funding by the Swedish Research Council (Vetenskapsrådet) in fierce national competition, as a part of the call for applications for Linneaus grants. Striving for a cure for diabetes  What does LUD

https://www.ludc.lu.se/our-research - 2025-07-25

Paul Franks’s research group Our researchAn assumption that underpins most public health and medicine is that risk profiles and treatment responses of individuals within a target population will approximate the average risk profile for the population. While this will be true for most people, many others deviate from these expectations, such that standard prediction models and interventions are ine

https://www.ludc.lu.se/research/genetic-and-molecular-epidemiology - 2025-07-25

Olga Göransson’s group Our researchProtein phosphorylation is a biological process that regulates most aspects of cellular life, and the enzymes that catalyze this reaction – protein kinases – constitute the largest family of enzymes encoded by the human genome.An overall aim of our research is to study the regulation and function of protein phosphorylation cascades that are important for the main

https://www.ludc.lu.se/research/protein-phosphorylation - 2025-07-25

Cecilia Holm’s group Our researchThe overall purpose of our research is to develop novel strategies for the prevention and treatment of diabetes and related metabolic disorders.Our group works mainly in two different areas. The first area involves the identification and evaluation of a new generation of probiotic bacterial strains that can be used to promote metabolic health. Bacterial strains wit

https://www.ludc.lu.se/research/molecular-endocrinology - 2025-07-25

The LUDC Early Career Network (previously DPLU) awards PhD student grants to ambitious doctoral students with promising projects. Grant recipients are announced at the annual LUDC Diabetes Research Day. An important aim of the student grant is to encourage doctoral students to come up with new research ideas and to train their grant application and research proposal skills. LUDC Early Career Netwo

https://www.ludc.lu.se/ludc-ecn/student-grant - 2025-07-25

The Leif C. Groop Award for Outstanding Diabetes Research is awarded annually by Lund University Diabetes Centre (LUDC) to a young investigator in the field of diabetes research who is active in any of the Nordic countries (Sweden, Denmark, Norway, Finland, Iceland). The prize money of 100,000 SEK is awarded for “scientific excellence that will benefit patients suffering from diabetes”. It may be

https://www.ludc.lu.se/ludc-ecn/leif-c-groop-award - 2025-07-25

Diabetes researcher Leif Groop is globally recognized for his contributions to diabetes research. This scholarship is awarded as a tribute to him. The young scientist scholarship aims to inspire young diabetes researchers to reach for high levels of novelty, quality, impact, and relevance in their scientific work. Lund University annually awards a scholarship of 200,000 SEK, which is intended to s

https://www.ludc.lu.se/ludc-ecn/leif-c-groop-young-scientist-scholarship - 2025-07-25

Early career researchers and doctoral students may benefit from guidance from a mentor, who can act as a positive role model and offer advice on a range of topics from experiments to career paths. Our mentor at LUDC is an experienced researcher who is available to all researchers and doctoral students at the centre. The mentor can share knowledge, act as advisor, and discuss research and career to

https://www.ludc.lu.se/ludc-ecn/mentorship - 2025-07-25

The LUDC Early Career Network would like to make it easier for you to advance in your career as a researcher. On this page, you will find useful links and resources. There are a lot of resources available for early career researchers at Lund University. Don’t miss the grants calendar where you can learn about new funding opportunities. You can also visit the Careers Centre and Future Faculty for i

https://www.ludc.lu.se/ludc-ecn/resources - 2025-07-25

Would you like to learn even more about diabetes research and expand your research network? The LUDC Early Career Network arranges a postgraduate course in diabetology every other year. The course is aimed at PhD students and postdoctoral fellows with an interest in diabetes research. It covers experimental research and molecular mechanisms of diabetes as well as clinical diagnostics and treatment

https://www.ludc.lu.se/ludc-ecn/postgraduate-course-diabetology - 2025-07-25

The LUDC Early Career Network (LUDC ECN) organises a wide range of activities. The overarching goal is to bring early career researchers and students together so they can meet, network, and exchange knowledge. The early career researchers’ day takes place during the fall. Join this day for talks and an after-work event. The activities bring early career researchers and students at LUDC together to

https://www.ludc.lu.se/ludc-ecn/activities - 2025-07-25

Philipp Kaldis’ group Our researchMany diseases that are caused by or associated with metabolic alterations are common today. Non-alcoholic fatty liver disease (NAFLD) and diabetes are examples of such diseases. Understanding changes in metabolism related to the development of diseases can help us identify new drug targets and therapeutic avenues. Metabolism can be studied on the levels of genes,

https://www.ludc.lu.se/research/metabolic-disorders-and-liver-disease - 2025-07-25

Hindrik Mulder’s group Our researchWe strive to understand why insulin-secreting beta cells fail to release sufficient amounts of insulin in type 2 diabetes.Pancreatic beta cells release the hormone insulin when blood glucose increases after a meal. Insulin lowers blood glucose levels and allows it to be taken up by tissues and stored as energy. This can then be used by the body between meals and

https://www.ludc.lu.se/research/diabetes-molecular-metabolism - 2025-07-25

Annelie Carlsson’s group Our researchThe overall purpose of our research is to improve childhood diabetes care to improve individualised treatment for every child, and to find triggers behind type 1 diabetes in children. The more specific aim of our research is to study the heterogeneity of childhood type 1 diabetes. Today we understand that type 1 diabetes affects children with different genetic

https://www.ludc.lu.se/research/pediatric-autoimmunity - 2025-07-25

Marju Orho-Melander’s group Our researchIn our research, we investigate large prospective population-based cohorts to understand the connections between cardiometabolic diseases (obesity, type 2 diabetes, cardiovascular disease) and human genetic variation. We also study the gut microbiome composition and function, circulating metabolites and proteins, and environmental factors with major focus on

https://www.ludc.lu.se/research/diabetes-cardiovascular-disease - 2025-07-25