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  We focus on understanding the pathogenetic mechanisms underlying leukemogenesis with a special focus on infant leukemia. In particular we are interested in unravelling the biological mechanisms that drive clonal evolution, the emergence of drug resistance, and the role of tumor heterogeneity in these processes, ultimately leading to new effective therapies. We use a combination of state-of-the-a

https://www.clinicalgenetics.lu.se/division-clinical-genetics/anna-hagstrom - 2026-06-01

    We make genetic and functional maps of cancer cell evolution in patients by analysing multiple tumour samples from the same patient. In particular, we focus on childhood cancer where we try to unravel the genetic mechanisms leading to relapse and treatment resistance.To achieve our aim, we use methods from species evolution (phylogenetics) to reconstruct the evolutionary history of individual

https://www.clinicalgenetics.lu.se/division-clinical-genetics/cancer-cell-evolution - 2026-06-01

The Database of Chromosome Aberrations and Gene Fusions in Cancer, established in 1980, is an attempt to register systematically all published cytogenetic aberrations reported in cancer, including patient and tumor characteristics, gene fusions identified by cytogenetics or massively parallel sequencing, and studies pertaining to the clinical relevance of cytogenetic aberrations and/or gene rearra

https://www.clinicalgenetics.lu.se/division-clinical-genetics/database-chromosome-aberrations-and-gene-fusions-cancer - 2026-06-01

  Soft tissue tumors (STT) constitute a heterogeneous group of approximately 100 distinct neoplasms, including more than 50 malignant subtypes, so-called sarcomas. Genetic analyses have shown that the clinical and biological variation among these neoplasms is reflected in their genotypes. While the diagnosis of STT has been improved by such genetic biomarkers, the use of genetic information for im

https://www.clinicalgenetics.lu.se/division-clinical-genetics/genetics-soft-tissue-tumors - 2026-06-01

The goal of our research is to increase our understanding of the leukemogenic process and to investigate the clinical impact of genetic/epigenetic abnormalities in pediatric acute lymphoblastic and myeloid leukemia. In order to achieve this goal, we use several types of “next generation sequencing”, such as whole genome sequencing, whole exome sequencing, and RNA sequencing, and various methylatio

https://www.clinicalgenetics.lu.se/division-clinical-genetics/geneticsepigenetics-pediatric-leukemia - 2026-06-01

   Gains and losses of whole chromosomes, termed aneuploidy, is seen in at least half of all tumors. How it affects tumorigenesis is still poorly understood. We use hyperdiploid (51-67 chromosomes) pediatric acute lymphoblastic leukemia (ALL) as a model to study aneuploidy, focusing on:How does the cell become aneuploid? We use large-scale sequencing and array-based analyses of bulk and single cel

https://www.clinicalgenetics.lu.se/division-clinical-genetics/aneuploidy-cancer - 2026-06-01

The highly complex genome of an osteosarcoma.Our aim is to develop new treatment strategies for patients with highly aggressive malignancies. To this end, we screen clinical tumor material for disease-causing mutations using deep sequencing technology and we manipulate genes of interest in cancer model systems to understand the true consequences of mutations.Most high-grade cancers harbor mutation

https://www.clinicalgenetics.lu.se/division-clinical-genetics/complex-genomes-cancer - 2026-06-01

https://www.clinicalgenetics.lu.se/department-clinical-genetics - 2026-06-01

Aneuploidy in Cancer Kajsa Paulsson - We aim to understand how aneuploidy - changes in the number of chromosomes – arises and affects cancer cells.  The Molecular Pathogenesis of Leukemia Anna Hagström- We aim to understand the mechanisms involved in hematopoietic cell transformation using a combination of genomic approaches and leukemia mouse models. Cancer Cell Evolution David Gisselsson Nord -

https://www.clinicalgenetics.lu.se/division-clinical-genetics - 2026-06-01

Register here for the reading group seminar on Kim Stanley Robinson's novel New York 2140. Name (required) Enter first and last name. E-mail address (required) Please enter your e-mail address. Dietary requirements Please let us know if you have any specific dietary requirements. The breakfast served will be vegetarian. Yes I want to borrow a book Leave this field blank

https://www.climatefutures.lu.se/form/registration-new-york-2140 - 2026-06-01

Register here for the reading group seminar on Jeff VanderMeer's trilogy Southern Reach. Name (required) Enter first and last name. E-mail address (required) Please enter your e-mail address. Dietary requirements Please let us know if you have any specific dietary requirements. The breakfast served will be vegetarian. Yes I want to borrow a book Leave this field blank

https://www.climatefutures.lu.se/form/registration-southern-reach - 2026-06-01

Register here for the reading group seminar on Jeff VanderMeer's trilogy Southern Reach. Name (required) Enter first and last name. E-mail address (required) Please enter your e-mail address. Dietary requirements Please let us know if you have any specific dietary requirements. The breakfast served will be vegetarian. Yes I want to borrow a book Leave this field blank

https://www.climatefutures.lu.se/form/registration-southern-reach-0 - 2026-06-01

Violent Climate Imaginaries: Science - Fiction - Politics VICTIM is funded by the Vice Chancellor of Lund University as part of a strategic collaboration with Universität Hamburg. It brings together established and emerging scholars from sociology, political science, criminology, literature studies and climate science. There are many techniques, ranging from scientific to literary and artistic, th

https://www.climatefutures.lu.se/collaborative-initiative/victim - 2026-06-01

Narrating Climate Futures is a collaborative initiative in which we explore the narratives and stories of climate futures. The initiative was launched in September 2017, and is funded by the Vice Chancellor of Lund University. Grappling with the challenge of climate change requires action in the present that addresses how we want the future to unfold. This requires the foresight of imagining alter

https://www.climatefutures.lu.se/collaborative-initiative - 2026-06-01

Fill in the form to sign up for the breakfast seminar "Rethinking Transport Futures" on September 24 8.15-9.45.   Name (required) Email (required) Dietary requirements The breakfast will be vegetarian. Leave this field blank

https://www.climatefutures.lu.se/form/registration-rethinking-transport-futures - 2026-06-01

Fill in the form to sign up for the breakfast seminar "Flooding in Skåne: Past Memories and Future Fears" on December 5, 8.15-9.45.  Name (required) Email (required) Dietary requirements The breakfast will be vegetarian Leave this field blank

https://www.climatefutures.lu.se/form/registration-flooding-skane-past-memories-and-future-fears - 2026-06-01

Fill in the form to sign up for the breakfast seminar "Transport Futures 1: Scenarios as narratives" on November 9, 8.15-9.45. Name Email (required) Dietary requirements The breakfast served will be vegetarian Leave this field blank

https://www.climatefutures.lu.se/form/registration-transport-futures-1-scenarios-narratives - 2026-06-01

Fill in the form to sign up for the breakfast seminar "Transport Futures 2: Stories about digitalisation" on November 22, 8.15-9.45. Name (required) Email (required) Dietary requirements The breakfast served will be vegetarian Leave this field blank

https://www.climatefutures.lu.se/form/registration-transport-futures-2-stories-about-digitalisation - 2026-06-01

Changing political and personal narratives of aviation, climate, and the good life in Sweden The takeoff of staying on the ground is funded by the Swedish research council Formas and involves researchers Kimberly Nicholas and Johannes Stripple together with the PhD student Sara Ullström. Continuation of business as usual trends for aviation are incompatible with meeting national and international

https://www.climatefutures.lu.se/takeoff-staying-ground - 2026-06-01

Fill in the form to join a trip to Kristianstads Konsthall where we'll visit the exhibition 'Man and Biosphere – Prekära Situationer' on January 11 2019. We meet at Lund C to jointly take the train at 12.41. Last day for registration is on January 9.  Name (required) Email (required) Comments (optional) Leave this field blank

https://www.climatefutures.lu.se/form/registration-man-and-biosphere-prekara-situationer - 2026-06-01