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Super-resolution microscopy (SRM) has revolutionized life sciences by overcoming the diffraction limit, enabling the visualization of biological structures at the nanoscale. Expansion Microscopy (ExM) has emerged as a powerful and accessible technique that enhances resolution by physically enlarging the specimen. Importantly, the principles of ExM provide a unique foundation for combinations with
Ten per cent of patients with colorectal cancer will develop peritoneal metastases. These metastases are known to have a lesser response to systemic chemotherapy than liver- and lung metastases. Randomized studies have shown that adding cytoreductive surgery and heated intraperitoneal chemotherapy (HIPEC) to this treatment gives a better chance of survival. Recently, a randomized study failed to s
Surface affinity, orientation and ion pairing are investigated in mixed and single solute systems of aqueous sodium hexanoate and hexylammonium chloride. The surface sensitive X-ray photoelectron spectroscopy technique has been used to acquire the experimental results, while the computational data have been calculated using molecular dynamics simulations. By comparing the single solute solutions w
Denna kandidatuppsats undersöker hur medelstora och stora svenska företag uppfattar datakvalitet vid design och implementering av AI-drivna chattbotar för internt bruk. Studien bygger på fem semistrukturerade intervjuer med yrkesverksamma som varit direkt involverade i utvecklingsarbetet och belyser hur organisationer ser på faktorer som datans noggrannhet, fullständighet och tillförlitlighet. ResThis bachelor’s thesis investigates how medium and large Swedish enterprises perceive data quality during the design and implementation of AI-powered chatbots for internal use. Through five semi-structured interviews with professionals directly involved in the chatbot development, the study explores organisational perspectives on data accuracy, completeness, and reliability, as well as key drivers
Språk- och litteraturcentrum Franska Litteraturlista ÄFRD02, franska, fortsättningskurs, 31-60 högskolepoäng Fastställd av Styrelsen för Sektion 3 2024-11-21 att gälla från VT25 Referenslitteratur för samtliga delkurser Wall, Kerstin; Béhar, Dennis; Ekman, Monika & Kronning, Hans (2014). Den franska grammatiken. Stockholm: Sanoma utbildning, ISBN 9789152327166 (336 sidor). NEs stora franska ordbok
https://www.uvet.lu.se/media/utbildning/dokument/kurser/AFRD02/20261/_FRD02_VT25.pdf - 2026-05-04
LITTERATURLISTA ABMA19: Museologi: Fysiska och digitala museer (15 hp) vårterminen 2025 Institutionen för kulturvetenskaper Avdelningen för ABM Godkänd av institutionsstyrelsen 2010, reviderad via kursplanegruppen 2024-12-06 Arcadius, Kerstin (1998). Museilandet tar form. I: Nordiska museet under 125 år. Stockholm: Nordiska museet, s. 155-163. ISBN 91-7108-442-8. (9 s.) Andersson, Suse (2020). Som
https://www.kultur.lu.se/media/utbildning/dokument/kurser/ABMA19/20251/ABMA19.Llitteraturlista.VT2025.docx - 2026-05-04
In this work, we present a parallel approach to complete and restricted active space second-order perturbation theory, (CASPT2/RASPT2). We also make an assessment of the performance characteristics of its particular implementation in the Molcas quantum chemistry programming package. Parallel scaling is limited by memory and I/O bandwidth instead of available cores. Significant time savings for cal
Double-sided three-dimensional porous silicon chips, 6 mm x 6 mm, covered with a 40 nm gold (nano)layer, were fabricated from a porous silicon wafer. Scanning electron microscopy along with electrochemical characterisation showed sample conductivity, mechanical stability, and high surface area of the thus fabricated devices, viz. 10 times higher electrochemically active surface area compared to th
Objective To assess mortality related to exposure to tuberculosis (TB) at home among children in urban areas of Guinea-Bissau. Methods In four suburban areas included in the demographic surveillance system of the Bandim Health Project in Bissau, the mortality of children aged <5 years living with an adult with TB was compared with the mortality of children in the general population. Results Childr
Through the combination of surface sensitive photoelectron spectroscopy and molecular dynamics simulation, the relative surface propensities of guanidinium and ammonium ions in aqueous solution are characterized. The fact that the N Is binding energies differ between these two species was exploited to monitor their relative surface concentration through their respective photoemission intensities.
A 25-year-old, with type I Diabetes Mellitus with a previous diagnosis of Protamine Allergy but not to human Insulin, started to notice anaphylactic reactions immediately after bolus with Insulin. Skin prick and intradermal test were positive to all insulins. Skin tests to other potential allergens resulted negative. Examination after bolus of Human Insulin revealed urticaria. Daily insulin requir
The oxygen-evolving complex (OEC) of photosystem II is the only natural system that can form O2 from water and sunlight and it consists of a Mn4Ca cluster. In a series of publications, Siegbahn has developed a model of the OEC with the quantum mechanical (QM) cluster approach that is compatible with available crystal structures, able to form O2 with a reasonable energetic barrier, and has a signif
BACKGROUND: Several different IgA-proteases exist in Haemophilus influenzae. The variants have been suggested to play differential roles in pathogenesis, but there is limited information on their distribution in clinical isolates. The objective of this study was to investigate the distribution of IgA-protease genotypes in H. influenzae and assess the association between IgA-protease genotype and t
There is a great interest in searching for new environmentally sustainable techniques to enhance the use of agricultural byproducts. In this work, a response surface methodology was used to study the influence of the two independent variables, temperature (25-200 degrees C) and extraction time (3-17 min), in the extraction of antioxidants by pressurized hot water extraction (PHWE) from industrial
We identify a mutation (D262N) in the erythroid-affiliated transcriptional repressor GFI1B, in an acute myeloid leukemia (AML) patient with antecedent myelodysplastic syndrome (MDS). The GFI1B-D262N mutant functionally antagonizes the transcriptional activity of wild-type GFI1B. GFI1B-D262N promoted myelomonocytic versus erythroid output from primary human hematopoietic precursors and enhanced cel
We previously reported a disease segregating causal germline mutation in a melanoma family and recurrent somatic mutations in metastasized tumours from unrelated patients in the core promoter region of the telomerase reverse transcriptase (TERT) gene. Here we show that the TERT promoter mutations, besides causing an increased gene expression, associate with increased patient age, increased Breslow
Background: Anillin (ANLN), an actin-binding protein required for cytokinesis, has recently been presented as part of a prognostic marker panel in breast cancer. The objective of the current study was to further explore the prognostic and functional value of ANLN as a single biomarker in breast cancer. Methods: Immunohistochemical assessment of ANLN protein expression was performed in two well cha
Involvement of the respiratory system, in particular dry airways and chronic obstructive pulmonary disease (COPD), is common in patients with primary Sjögren’s syndrome (pSS). As respiratory symptoms are also common in pSS patients and may have different etiologies, we wanted to evaluate the amount and impact of respiratory symptoms in out-patients with pSS and to assess if such symptoms are relat
The nutrition transition promotes the development of childhood obesity. Currently, Mexico is affected by this serious public health problem. The nutritional and functional characterization of a whole menu has a number of advantages over the study of single nutrients. Since breakfast is considered the most important meal of the day, this study aimed to evaluate the metabolite profile produced by in
