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Modelling of gene regulatory and spatial mechanisms which pattern the early human neural tube

Hur en enda befruktad äggcell kan utvecklas till ett igenkännligt foster över loppet av några månaders tid är ett fascinerande mysterium. Vi vet nog alla att celler kan dela sig, och att det är på så vis som våra kroppar växer under fosterstadiet. Men en cell som delar sig kommer ge upphov till två identiska dotterceller. Hur är det då möjligt att en äggcell kan ge upphov till alla de helt olika sTissue patterning during development is thought to be driven largely by gene regulatory responses to spatial gradients of molecular signals, known as morphogens. In this thesis, early patterning of the human neural tube is studied using two different gene regulatory network models. The models portray patterning in the rostral-caudal direction as a response to gradients of WNT and FGF signalling. T

Anetta Bolejko

Associate professor, Principal investigator, PhD Anetta Bolejko, PhD, Associate professor of radiography, Principal investigator, Project manager, Registered radiographer, RN Affiliation: Research group LUCI, Department of Translational medicine, Lund University. Department of Medical imaging and physiology, Skåne University Hospital, Malmö. Employment: Academic professional development lead in ra

https://www.luci.lu.se/en/anetta-bolejko - 2026-05-05

Kurslitteratur mven16 ht15 26okt15

Kurslitteratur MVEN16_HT15_26okt15 Kurslitteratur MVEN16, HT15 2015-10-26 MVEN16 KURSLITTERATUR, HT15 OBS! Fler artiklar, rapporter o.dyl. kan tillkomma under kursens gång. Kursböcker Boyce, T., Lewis, J. (eds.) (2009). Climate Change and the Media. Global Crises and the Media Series. Peter Lang Pub Inc. (261 sid). (OBS! Svårtillgänglig; utvalda kapitel tillhandahålles) Bulkeley, H. and P. Newell

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/kurslitteratur_mven16_ht15_26okt15.pdf - 2026-05-06

Husstyrelsen 2023-03-15 Protokoll

1 (5) LUNDS UNIVERSITET CAMPUS HELSINGBORG Protokoll Sammantradesdatum 2023-03-15 Diarienummer STYR2023/689 Utveckl i ngsen heten Protokoll Campus husstyrelse Narvarande Charlotta Johnsson Jerker Jacobsson Veronica Aberg Cecilia Nygren ersatter Mozghan Zahrison. Maria Bergendahl Arvidsson universitetslektor, Socialhogskolan Magdalena Unosson lokalcontroller, LTH Gabriella Nilsson prefekt, Inst. ku

https://www.ch.lu.se/internt/sites/ch.lu.se.internt/files/2023-11/Husstyrelsen%202023-03-15%20protokoll.pdf - 2026-05-06

RWI goes to COP27 Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law

RWI goes to COP27 Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Wor

https://rwi.lu.se/news-tags/rwi-goes-to-cop27/ - 2026-05-05

Transcription Factor Binding Site Analysis Identifies FOXO Transcription Factors as Regulators of the Cutaneous Wound Healing Process.

The search for significantly overrepresented and co-occurring transcription factor binding sites in the promoter regions of the most differentially expressed genes in microarray data sets could be a powerful approach for finding key regulators of complex biological processes. To test this concept, two previously published independent data sets on wounded human epidermis were re-analyzed. The prese

Acid-Base Speciation of Carboxylate Ions in the Surface Region of Aqueous Solutions in the Presence of Ammonium and Aminium Ions

The acid base speciation of surface-active carboxylate ions in the surface region of aqueous solutions was studied with synchrotron-radiation-based photoelectron spectroscopy. The protonated form was found at an extraordinarily large fraction compared to that expected from the bulk pH. When adding salts containing the weak acid NH4+ to the solution, the fraction of the acidic form at the surface i

Offentlig service på entreprenad- exemplet Nibblegården och Ärtan

Denna uppsats behandlar utkontrakteringar i offentlig sektor och som praktikfall har utkontrakteringen av äldreboendena Nibblegården och Ärtan i Lunds kommun valts. Själva syftet med uppsatsen är att få en uppfattning om vilka effekter som uppkommer vid utkontrakteringar. I uppsatsen diskuteras även vad som bör beaktas vid utkontrakteringsbeslut (eller återtagande av utkontrakterad verksamhet). De

The Determinants and Impacts of Executive Stock Options

The thesis main objective is to establish the determinants for granting executive stock options and to examine their impact on performance for firms listed on OMXS30. The analysis is based on accounting data gathered from annual reports and Thomson Datastream. The empirical results display that firms grant stock options to mitigate the principal-agent problem. Furthermore, risk proves to be positi

Multicomponent inverse modeling of supercritical fluid extraction of carotenoids, chlorophyll A, ergosterol and lipids from microalgae

The fundamentals of analyte extractable fraction, solubility, partitioning and mass transfer resistance in supercritical fluid extraction were studied using inverse modeling. These phenomena are essential for understanding, predicting and optimizing the supercritical fluid extraction process. Carotenoids, chlorophyll A, ergosterol and total lipids were extracted from the microalgae Chlorella sp. T

Antioxidant activity of phosphatidyl derivatives of hydroxytyrosol in edible oils

A comparative study of the antioxidant activity of hydroxytyrosol (HT) and phosphatidyl derivatives of hydroxytyrosol (PHT) added at increasing concentrations to diverse edible oils (lard oil, refined olive oil, and diacylglycerol-rich oil) was performed. Antioxidant activity index was estimated as the ratio of induction time in presence of the compounds to induction time in their absence, after o

Youth handball concussion prevention strategies: A workshop-based study with experts and end users

Sport-related concussion (SRC) is a serious injury in youth team sports, including handball. While research on the prevention of SRC has made progress over the past 5 years, prevention strategies are lacking in handball. The aim was to explore and develop strategies focusing on information, rules and training that may prevent concussion in youth handball by incorporating knowledge from experts and

No evidence of colour-based microhabitat choice in a polymorphic marine snail

Microhabitat choice has been proposed as a mechanism contributing to the maintenance of colour polymorphism in marine gastropods, based on observed associations between shell colour and microhabitat in certain species (e.g. Littorina saxatilis). To examine this hypothesis, different colour morphs of L. saxatilis were studied following a mark-recapture experimental design to assess whether this spe

Dietary recommendations for patients allergic to Anisakis simplex

BACKGROUND: Anisakis simplex, a fish parasite, causes allergic urticaria, angioedema and anaphylactic shock through an IgE-mediated hypersensitivity mechanism. Consensus on the dietary recommendations that should be given to allergic patients is lacking. Our objective was to evaluate the usefulness of different types of diets in preventing further reactions in patients allergic to A. simplex. METH

Downregulation of Angiogenesis Factors, VEGF and PDGF, after Rapid IgE Desensitization and Oral Immunotherapy in Children with Food Allergy

Background. Angiogenesis has a key role in several conditions and is regulated by several factors such as the platelet-derived growth factor (PDGF) or the vascular endothelial growth factor (VEGF). The goal of this study was to investigate the possible role of PDGF and VEGF in a group of patients with severe food allergy. Methods. We design a prospective longitudinal study (n = 30) with patients w

Mono endo-6- And bis endo,endo-12-N,N-diethylcarbamoyl derivatives of Tröger’s Base. Synthesis and exo-endo isomerization study

An efficient synthetic route to the mono-endo-6- and bis-endo,endo-6,12-N,N-diethylcarbamoyl derivatives of Tröger’s base (TB), endo-7 and endo-8, is reported. Studies of reaction time, proton source, and additive allowed establishment of optimized conditions for the conversion of exo-7 into the corresponding isomer endo-7. With a longer reaction time, the exo,exo-6,12 bis-carbamoyl derivative exo

Window-opening and indoor climate in new multifamily-dwellings : A questionnaire survey

The apartment-block of Flagghusen in Malmö in the south of Sweden was built and designed with the intention to achieve a lower energy use compare to the regulations and a good indoor environment. The outcome of this ambition was evaluated in a first report in 2010 that showed that the overall notion of the perceived indoor climate in the apartments were good but that the measured energy use exceed

Modeling the evolution of culture-adapted human embryonic stem cells

The long-term culture of human embryonic stem (ES) cells is inevitably subject to evolution, since any mutant that arises with a growth advantage will be selectively amplified. However, the evolutionary influences of population size, mutation rate, and selection pressure are frequently overlooked. We have constructed a Monte Carlo simulation model to predict how changes in these factors can influe