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Are aggressive pituitary tumors and carcinomas two sides of the same coin? Pathologists reply to clinician’s questions

Pituitary adenohypophyseal tumors are considered as benign and termed “adenomas”. However, many tumors are invasive and a proportion of these exhibit an “aggressive behavior” with premature death due to progressive growth. Only very rare (0.2%) tumors with metastases are considered malignant and termed “carcinomas”. Taking into account this variability in behavior and the oncological definition, p

Self-efficacy, recovery and psychological wellbeing one to five years after heart transplantation : a Swedish cross-sectional study

Background: Self-efficacy refers to a person´s confidence in carrying out treatment-related activities and constitutes the foundation of self-management as well as long-term follow-up after heart transplantation. Exploring the heart recipients´ experiences by means of self-report instruments provides healthcare professionals with valuable information on how to supply self-management support after

Evaluating macrophage migration inhibitory factor 1 expression as a prognostic biomarker in colon cancer

Objective: Several studies indicate that macrophage migration inhibitory factor 1 plays a role for tumor progression in colon cancer. We investigated whether determination of migration inhibitory factor 1 mRNA expression levels in lymph nodes of colon cancer patients could be used as a prognostic marker. Methods: Expression levels of migration inhibitory factor 1 and carcinoembryonic antigen mRNAs

Accurate Backbone 13C and 15N Chemical Shift Tensors in Galectin-3 Determined by MAS NMR and QM/MM : Details of Structure and Environment Matter

Chemical shift tensors obtained from solid-state NMR spectroscopy are very sensitive reporters of structure and dynamics in proteins. While accurate 13C and 15N chemical shift tensors are accessible by magic angle spinning (MAS) NMR, their quantum mechanical calculations remain challenging, particularly for 15N atoms. Here we compare experimentally determined backbone 13Cα and 15NH chemical shift

Carving the body at its joints : Does the way we speak about the body shape the way we think about it?

Looking at the way different linguistic communities speak about a universally shared domain of experience raises questions that are central to the language sciences. How can we compare meaning across languages? What is the interaction between language, thought, and perception? Does linguistic diversity entail linguistic relativism? The literature on the naming systems of the body across languages

Global wave climate based on the JMA/MRI-AGCM3.2 climate change projection

In this study, global wave climates for present and future climates are simulated by the WAM model, based on wind climate data from the JMA/MRI-AGCM3.2 climate change projection. This study is based on two 6-hourly wind data sets, covering two periods of 1979-2003 (present climate) and 2075-2099 (future climate). These wind data are used to run the WAM model for generating output of wave character

Lunar synchronization of daily activity patterns in a crepuscular avian insectivore

Biological rhythms of nearly all animals on earth are synchronized with natural light and are aligned to day-and-night transitions. Here, we test the hypothesis that the lunar cycle affects the nocturnal flight activity of European Nightjars (Caprimulgus europaeus). We describe daily activity patterns of individuals from three different countries across a wide geographic area, during two discrete

A complete time-calibrated multi-gene phylogeny of the european butterflies

With the aim of supporting ecological analyses in butterflies, the third most species-rich superfamily of Lepidoptera, this paper presents the first time-calibrated phylogeny of all 496 extant butterfly species in Europe, including 18 very localised endemics for which no public DNA sequences had been available pre-viously. It is based on a concatenated alignment of the mitochondrial gene COI and u

Coulomb Excitation of Proton-rich N = 80 Isotones at HIE-ISOLDE

A projectile Coulomb-excitation experiment was performed at the radioactive ion beam facility HIE-ISOLDE at CERN. The radioactive 140Nd and 142Sm ions were post accelerated to the energy of 4.62 MeV/A and impinged on a 1.45 mg/cm2-thin 208Pb target. The γ rays depopulating the Coulomb-excited states were recorded by the HPGe-array MINIBALL. The scattered charged particles were detected by a double

3D-Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices

Compartmentalized microfluidic platforms are an invaluable tool in neuroscience research. However, harnessing the full potential of this technology remains hindered by the lack of a simple fabrication approach for the creation of intricate device architectures with high-aspect ratio features. Here, a hybrid additive manufacturing approach is presented for the fabrication of open-well compartmental

Favorable Propagation with User Cluster Sharing

We examine the favorable propagation (FP) behavior of a massive multi-user multiple-input-multiple-output (MU-MIMO) system equipped with a uniform linear array (ULA), horizontal uniform rectangular array (HURA) or uniform circular array (UCA) using a ray-based channel model with user cluster sharing. We demonstrate FP for these systems and provide analytical expressions for the mean-squared distan

Hydrophobic and Hydrophilic Extractives in Norway Spruce and Kurile Larch and Their Role in Brown-Rot Degradation

Extractives found in the heartwood of a moderately durable conifer (Larix gmelinii var. japonica) were compared with those found in a non-durable one (Picea abies). We identified and quantified heartwood extractives by extraction with solvents of different polarities and gas chromatography with mass spectral detection (GC-MS). Among the extracted compounds, there was a much higher amount of hydrop

Till det sociala arbetets försvar : - vad försvarar forskare och praktiker i socialt arbete?

Syftet med den här texten är att stå upp till det professionella sociala arbetets försvar genom ett kritiskt förhållningssätt till både forskare och socionomer/praktiker i socialt arbete. Vad gäller forskare riktas blicken framförallt mot forskarkarriären, och vad gäller socionomer uppmärksammas yrkesutövningen på den fältbaserade praktiken med fokus på kommunal aktivering av arbetslösa och brukar

Deadly violence in Sweden: Profiling offenders through a latent class analysis

BackgroundSweden has in recent years witnessed increasing rates of firearm-related violence and homicide, which has contributed to increased rates of deadly violence. Attempts to profile offenders committing such crimes are of major importance, because such efforts may contribute to better preventive measures. We therefore aimed to study the characteristics of individuals convicted and/or suspecte