BACKGROUND: Pancreatic cancer is a major cause of cancer-related mortality. The identification of effective biomarkers is essential in order to improve management of the disease. Yes-associated protein 1 (YAP1) is a downstream effector of the Hippo pathway, a signal transduction system implicated in tissue repair and regeneration, as well as tumorigenesis. Here we evaluate the biomarker potential

Who owns the Catholic Church?

This is for her is a performance about torture and therapy. On stage are two women. A victim and a perpetrator. A patient and a therapist. Torture and therapy always involve two people. Torture is about destroying the trust in other people. It only takes a moment, but it takes a lifetime to get back to everyday life again.

I Love You You Love Me is a performance about torture and therapy.

Precarious Life is a performance lecture about terror and autoimmune diseases. Terror and autoimmune diseases have something in common: neither can be defeated, because the threat comes from within. The performance has a personal and political aim. The personal aim consists in understanding why the body suddenly attacks itself. The political consists in examining the autoimmunity of terror and in

As a school nurse, it can be challenging to make values and philosophy useful in the context of a busy and stressful workday. However, values and philosophy can help guide school nurses in their profession. This article proposes strategies for how school nurses can make their school nurse’s values and philosophy visible. The first step in formulating a school nurse philosophy is to identify overal

OBJECTIVES: This study provides a detailed analysis of the global and regional burden of cancer due to occupational carcinogens from the Global Burden of Disease 2016 study.METHODS: The burden of cancer due to 14 International Agency for Research on Cancer Group 1 occupational carcinogens was estimated using the population attributable fraction, based on past population exposure prevalence and rel

Background and purpose — Children and young adults with cerebral palsy (CP) have an increased risk of developing scoliosis, with a prevalence ranging from 11% to 29%. Information on risk factors for the emergence and progression of scoliosis is inconclusive. This study aimed to develop a risk score based on 5-year-old children with CP to predict the risk of scoliosis before the age of 16. Patients

The radiation of Anolis lizards in the Caribbean is associated with a diversification of the functional match between morphology, habitat use, and locomotor performance. It has been hypothesized that the microhabitat a lizard is reared in can achieve a similar fit of form and function within a species. This predicts that plasticity in the locomotor apparatus is accompanied by changes in perching b

Packaging developers in the food industry must consider several, sometimes conflicting, environmental requirements on packaging along with an already complex combination of marketing, logistics and production requirements. Existing methods for the environmental evaluation of packaging either focus on a limited amount of environmental packaging criteria (such as recyclability or renewable content)

A method is presented that combines advanced experimental and numerical techniques in the determination of constitutive parameters. The general principle is that a specimen, producing a non-homogeneous stress state, is deformed rapidly. Load and deformation is recorded during the deformation and the event is also simulated using FEM. For the numerical calculation a set of constitutive parameters i

In this work, a combination of sonication and carbon dioxide expanded liquid extraction (SA-CXLE) is used for the first time for the extraction of lipids from berry seeds. Three solvents (ethanol, methanol and ethyl lactate) are screened for the best recoveries of total lipids. Ethanol is selected due to its efficiency, greenness and sustainability. The effects of operation variables including tem

Objective: To estimate the association between molecular or imaging inflammatory biomarkers at 2 years after anterior cruciate ligament (ACL) injury and patient-reported outcomes at 5 years. Methods: For 116 ACL-injured patients, molecular biomarkers of inflammation (synovial fluid and serum cytokines) and Hoffa- and effusion-synovitis as visualized on magnetic resonance imaging (MRI) were assesse

Critique of the Corruption Perceptions Index of Transparency International which has made Denmark the world's least corrupt country, despite continuing corruption scandals in Denmark. The Corruption Perception Index does not really address the kind of corruption we have in the Nordic countries.