Search results

Filter

Filetype

Your search for "*" yielded 546394 hits

The family as the health producer--when spouses act strategically.

The Grossman model has been extended recently in order to take account of the fact that most people lead their lives in a family--using frameworks in which family members, respectively, (a) have common preferences and (b) are Nash-bargainers. These models, however, do not consider individual incentives for behaving strategically. In the model presented in this paper, spouses interact strategically

Enhanced benefit of increasing interferon beta-1a dose and frequency in relapsing multiple sclerosis - The EVIDENCE study

Background: The EVIDENCE (Evidence of Interferon Dose-Response: European North American Comparative Efficacy) Study demonstrated that patients with multiple sclerosis (MS) who initiate interferon beta-la therapy with 44 μ g 3 times weekly (TIW) were less likely to have a relapse or activity on magnetic resonance imaging (MRI) compared with those who initiate therapy at a dosage of 30 μ g 1 time we

Deuteron and antideuteron production in Au+Au collisions at root s(NN)=200 GeV

The production of deuterons and antideuterons in the transverse momentum range 1.1 < p(T)< 4.3 GeV/c at midrapidity in Au+Au collisions at root s(NN) = 200 GeV has been studied by the PHENIX experiment at RHIC. A coalescence analysis, comparing the deuteron and antideuteron spectra with that of proton and antiproton, has been performed. The coalescence probability is equal for both deuterons and a

Concentration evaluation method using broadband absorption spectroscopy for sulfur dioxide monitoring

We report on an approach for sulfur dioxide monitoring using broadband absorption spectroscopy in the ultraviolet spectral range. The method was applied in real-time measurements and has the advantage of straightforward data evaluation, limited susceptibility for interference from other gases, and low degree of complexity compared with other real-time optical detection techniques having the same p

Apomorphine in the treatment of Parkinson's disease

Apomorphine is a potent, nonselective, direct-acting dopamine-receptor agonist. Given subcutaneously, it has a rapid onset of antiparkinsonian action qualitatively comparable to that of levodopa. Despite its long history, it was not until peripheral dopaminergic side effects could be controlled by oral domperidone that the clinical usefulness of apomorphine in Parkinson's disease began to be inves

The gas phase reaction between CO2 and lanthanide atoms. A test of a model for the isokinetic effect

Using literature data on the gas phase reaction between free lanthanide atoms and carbon dioxide, we have found an isokinetic relation for seven of the twelve investigated elements with an isokinetic temperature, T-iso of 2500 +/- 330 K. This value is analyzed in the framework of the model of selective energy transfer, SET, indicating that metal-CO2 complexes are formed as pre-reaction states. The

Persistent pain after groin hernia surgery: a qualitative analysis of pain and its consequences for quality of life

Despite a high prevalence of persistent groin pain after hernia repair, the specific nature of the pain and its clinical manifestation are poorly known. The aim of this study was to determine the type of post-herniorrhaphy pain and its influence on daily life. In order to assess long-term pain qualitatively and to explore how it affects quality of life, 100 individuals with persisting pain, identi

Myosin 5a controls insulin granule recruitment during late-phase secretion.

We have examined the importance of the actin-based molecular motor myosin 5a for insulin granule transport and insulin secretion. Expression of myosin 5a was downregulated in clonal INS-1E cells using RNAinterference. Stimulated hormone secretion was reduced by 46% and single-cell exocytosis, measured by capacitance recordings, was inhibited by 42% after silencing. Silencing of Slac-2c/MYRIP, whic

Sex and muscle structural lipids in obese subjects - an impact on insulin action?

Background Long-chain polyunsaturated fatty acid (LCPUFA) especially the n-3-FA of skeletal muscle phospholipids may facilitate insulin action, whereas saturated and trans-FA act oppositely. Community studies show that non-diabetic weight matched obese men and women display similar insulin resistance, despite the fact that an android fat distribution is detrimental to insulin action. The increased

Effects of Aggregates on Mixed Adsorption Layers of Poly(ethylene imine) and Sodium Dodecyl Sulfate at the Air/Liquid Interface

We have exploited the spatial and kinetic resolution of ellipsometry to monitor the lateral movement of inhomogeneous patches of material in mixed adsorption layers of poly(ethylene imine) and sodium dodecyl sulfate at the air/liquid interface. We show that the choice of sample preparation methods can have a profound effect on the state of the interface for chemically equivalent samples. The exten

Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) in early knee osteoarthritis.

Delayed contrast-enhanced MRI of cartilage (dGEMRIC) is a noninvasive technique to study cartilage glycosaminoglycan (GAG) content in vivo. This study evaluates dGEMRIC in patients with preradiographic degenerative cartilage changes. Seventeen knees in 15 patients (age 35-70) with arthroscopically verified cartilage changes (softening and fibrillations) in the medial or lateral femoral compartment

Application of supercritical carbon dioxide(scCO(2)) for the extraction of glycolipids from Lactobacillus plantarum B-01

Process parameters for the extraction of glycolipids by scCO(2) from Lactobacillus plantarum B-01 were optimized by carrying out a two-level fractional design experiment. The highest glycolipids extract yield was obtained at 250 bar, 40 degrees C, CO2 flow rate, 10 g/min and hydrometanolic co-solvent, 9.3% (v/v). In the lipid extracts the carbohydrate moiety of glycolipids and in phospholipids pho

Clinical manifestations of atherosclerosis in an elderly population are related to plasma neopterin, NGAL and endothelin-1, but not to Chlamydia pneumoniae serology.

BACKGROUND: Inflammatory mediators secreted by leukocytes are implicated in atherogenesis. Chlamydia (C.) pneumoniae infection has been suggested as a trigger of this process. We investigated relationships between C. Pneumoniae serology, inflammatory mediators and symptomatic cardiovascular disease in old age. METHODS: In a cross-sectional study at baseline with a prospective 4 year follow-up, int

Assessment of volume of fluid and immersed boundary methods for droplet computations

The volume of fluid (VOF) and immersed boundary (IB) methods are two popular computational techniques for multi-fluid dynamics. To help shed light on the performance of both techniques, we present accuracy assessment, which includes interfacial geometry, detailed and global fluid flow characteristics, and computational robustness. The investigation includes the simulations of a droplet under stati

Improved HPLC method for carbohydrate-deficient transferrin in serum

Background: There is need for a reference method for transferrin glycoforms in serum to which routine immunologic methods for the alcohol marker carbohydrate-deficient transferrin (CDT) can be traceable. We describe an improved HPLC method for transferrin glycoforms. Methods: Transferrin was iron-saturated by mixing the serum with ferric nitrilotriacetic acid, and lipoproteins were precipitated wi

Tone production, tone perception and Kammu tonogenesis

The Northern and Western dialects of the Mon-Khmer language Kammu use fundamental frequency to distinguish words, while the Eastern dialect relies on the contrastive voicing of initial consonants to distinguish words which display an F0 contrast in the other dialects. The production and perception of tones in the three dialects is investigated, using recordings and perception tests. As expected, N

Purification of caveolae by affinity two-phase partitioning using biotinylated antibodies and NeutrAvidin-dextran

A new concept for affinity two-phase partitioning was tested. The partitioning was based on the interaction of target membranes with a primary antibody which, in turn, interacted with a biotinylated secondary antibody and NeutrAvidin-dextran in a poly(ethylene glycol)/dextran two-phase system. Caveolae selectively redistributed from the top phase to the NeutrAvidin-dextran-containing bottom phase