Background and aims: We have previously found increased levels of the cysteine protease legumain in plasma and plaques from patients with carotid atherosclerosis. This study further investigated legumain during acute cardiovascular events. Methods: Circulating levels of legumain from patients and legumain released from platelets were assessed by enzyme-linked-immunosorbent assay. Quantitative PCR

Objective: The TLR3/cGAS-STING-IFN signaling has recently been reported to be disturbed in colorectal cancer due to deregulated expression of the genes involved. Our study aimed to investigate the influence of potential regulatory variants in these genes on the risk of sporadic colorectal cancer (CRC) in a Czech cohort of 1424 CRC patients and 1114 healthy controls. Methods: The variants in the TL

Mobile head-worn eye trackers allow researchers to record eye-movement data as participants freely move around and interact with their surroundings. However, participant behavior may cause the eye tracker to slip on the participant’s head, potentially strongly affecting data quality. To investigate how this eye-tracker slippage affects data quality, we designed experiments in which participants mi

We present GlassesViewer, open-source software for viewing and analyzing eye-tracking data of the Tobii Pro Glasses 2 head-mounted eye tracker as well as the scene and eye videos and other data streams (pupil size, gyroscope, accelerometer, and TTL input) that this headset can record. The software provides the following functionality written in MATLAB: (1) a graphical interface for navigating the

Political connection in China is often tested for correlation with business success and government support under a suspicion that connected entrepreneurs enjoy special favors and protection. Research evidence is mixed. In revisiting the debate on political capital in China, we apply a socially embedded perspective on political connection. To this end we introduce two methodological innovations: (a

Background: The relevance of PTSD symptoms to outcomes of Cognitive Behavioral Therapy (CBT) for chronic pain is unclear. This study examines whether (a) traumatic exposure or the severity of PTSD symptoms at pre‐treatment predict outcomes (pain intensity/interference) (b) participation in this treatment is associated with reduced PTSD symptoms, and (c) any observed changes in PTSD symptoms are me

Generalising a construction of Falconer, we consider classes of 𝐺𝛿-subsets of ℝ𝑑 with the property that sets belonging to the class have large Hausdorff dimension and the class is closed under countable intersections. We relate these classes to some inhomogeneous potentials and energies, thereby providing some useful tools to determine if a set belongs to one of the classes

AIMS/HYPOTHESIS: Substantial deposition of the extracellular matrix component hyaluronan (HA) is characteristic of insulitis in overt type 1 diabetes. We investigated whether HA accumulation is detectable in islets early in disease pathogenesis and how this affects the development of insulitis and beta cell mass.METHODS: Pancreas tissue from 15 non-diabetic organ donors who were positive for islet

Denna bok belyser hot mot undervattenskablar som en särpräglad kritisk infrastruktur, vilken kan användas för cyberspionage och underrättelseinhämtning. Hotbildens analys mynnar ut i frågan om det nuvarande folkrättsliga systemet är tillräckligt ändamålsenligt för att skydda kabelsystemen mot åverkan genom staters och/eller icke-statliga aktörers försorg och för att stärka internationell cybersäke

Denna serie (ISBN 978-91-986003-0-8) innehåller den litauenjudiske statsmannen, folkrättsjuristen och sionistiske diplomaten Shimshon Rosenbaums (1859–1934) samlade verk på originalens språk med fullständiga översättningar till engelskan. I band 1 återges hans skrifter om folkrätt, sionism samt den judiska nationens självbestämmande, autonomi och statlighet.

Denna serie (ISBN 978-91-986003-0-8) innehåller den litauenjudiske statsmannen, folkrättsjuristen och sionistiske diplomaten Shimshon Rosenbaums (1859–1934) samlade verk på originalens språk med fullständiga översättningar till engelskan. I band 2 samlas hans artiklar och tal om folkrätt, sionism samt den judiska nationens självbestämmande, autonomi och statlighet.