Hindrik Mulder’s group Our researchWe strive to understand why insulin-secreting beta cells fail to release sufficient amounts of insulin in type 2 diabetes.Pancreatic beta cells release the hormone insulin when blood glucose increases after a meal. Insulin lowers blood glucose levels and allows it to be taken up by tissues and stored as energy. This can then be used by the body between meals and

https://www.ludc.lu.se/research/diabetes-molecular-metabolism - 2025-05-23

Annelie Carlsson’s group Our researchThe overall purpose of our research is to improve childhood diabetes care to improve individualised treatment for every child, and to find triggers behind type 1 diabetes in children. The more specific aim of our research is to study the heterogeneity of childhood type 1 diabetes. Today we understand that type 1 diabetes affects children with different genetic

https://www.ludc.lu.se/research/pediatric-autoimmunity - 2025-05-23

Marju Orho-Melander’s group Our researchIn our research, we investigate large prospective population-based cohorts to understand the connections between cardiometabolic diseases (obesity, type 2 diabetes, cardiovascular disease) and human genetic variation. We also study the gut microbiome composition and function, circulating metabolites and proteins, and environmental factors with major focus on

https://www.ludc.lu.se/research/diabetes-cardiovascular-disease - 2025-05-23

Gustav Smith’s group Our researchHeart disease remains the leading cause of death globally. Major transitions in the spectrum of heart disease have occurred over time while the end-result, failure of the human heart to maintain sufficient output of blood for the demands of the body, referred to as heart failure, remains a common condition with high mortality rate. Notably, the importance of obesit

https://www.ludc.lu.se/research/molecular-epidemiology-and-cardiology - 2025-05-23

Do you want to learn more about diabetes research and expand your research network? The postgraduate course in diabetology runs every other year. The postgraduate course in diabetology is arranged every other year by the LUDC Early Career Network, a network of young researchers at Lund University Diabetes Centre (LUDC). The course is aimed at PhD students and postdoctoral fellows with an interest

https://www.ludc.lu.se/courses-and-training/phd-course-diabetology - 2025-05-23

Are you interested in learning more about diabetes research? On this webpage you can find information about courses and training opportunities at Lund University Diabetes Centre. LUDC ECN is a network of young researchers and students at Lund University Diabetes Centre. Young researchers within this network arrange a postgraduate course in diabetes research every other year. The aim of the course

https://www.ludc.lu.se/courses-and-training - 2025-05-23

Are you enrolled in the Biomedicine Master Programme at Lund University? The course in metabolic diseases is part of the programme and is taught by staff at LUDC. The course provides students with specialisation in cell biology and human physiology. The course focuses on (some of the) endocrine and metabolic diseases that are included in the strong research areas at Lund University.The course star

https://www.ludc.lu.se/courses-and-training/course-metabolic-diseases - 2025-05-23

Below you will find dissertations by doctoral students at Lund University, affiliated with Lund University Diabetes Centre (LUDC) and the strategic research area EXODIAB (Excellence of Diabetes Research in Sweden). 2024 Regulation of insulin secretion by local and circulating factors - Investigations on islet proteins and microRNAsEfraim WestholmMediators, Metabolites and Atypical Immune Cells in

https://www.ludc.lu.se/courses-and-training/doctoral-theses-phd-students - 2025-05-23

SRA Workshop series I would like to register for the workshop on Multidisciplinary impact pathways - Defining project outcomes, outputs and impact. Date: Tuesday November 22nd Time: 8.30-12.00 Location: LU Clinical Research Centre (Dept of Clinical Sciences Malmö) Malmö. Please register latest by November 15th. Surname (required)    Family name (required)    LU email address (required)    I have t

https://www.ludc.lu.se/form/multidisciplinare-impact-pathways-defining-project-outcomes-outputs-and-impact - 2025-05-23

Emily Sonestedt’s group Our researchNutritional epidemiology uses epidemiological methods to examine the association between diet and disease. In our research group, we investigate whether food habits influence the risk of developing various diseases, including cardiovascular disease, type 2 diabetes, and cancer. We use large population studies, mainly the Malmö Diet and Cancer cohort, which was e

https://www.ludc.lu.se/research/nutritional-epidemiology - 2025-05-23

Peter Spégel’s group Our researchOur research aims to understand metabolism and how it is altered in diabetes and obesity. Our hope is that knowledge on metabolic dysregulation in obesity-associated diseases and changes in metabolism associated with life-style interventions can aid us in designing sustainable life-style recommendations. The overall purpose is to enhance our understanding of metabo

https://www.ludc.lu.se/research/diabetes-obesity-and-metabolism - 2025-05-23

Karin Stenkula’s group Our researchOur research is focused on exploring the molecular mechanisms regulating adipocyte function, both normal and in the insulin-resistant state, using experimental cell biology methods and sophisticated microscopy techniques at a single cell level. AimsOur overall aim is to identify the mechanisms that cause adipocyte dysfunction. Specifically, we want to understand

https://www.ludc.lu.se/research/glucose-transport-and-protein-trafficking - 2025-05-23

Nils Wierup’s group Our researchThe purpose of our research is to understand how each islet cell type and each enteroendocrine cell type in the gut is affected in type 2 diabetes. Impaired islet function is necessary for type 2 diabetes to develop. Less is known on the role of gut hormones in type 2 diabetes pathophysiology.  By identifying type 2 diabetes-induced alterations we foresee that we wi

https://www.ludc.lu.se/research/neuroendocrine-cell-biology - 2025-05-23

Enming Zhang’s group Our researchThe deterioration of pancreatic islet cell functions is a prominent feature of diabetes. Islet cells express various cellular molecular sensors, for example ion channels. These respond to a variety of stimuli, such as voltage, chemical ligands, and mechanical/osmotic stimuli. The stimulus-sensor interactions typically regulate cellular functions to adapt to an abno

https://www.ludc.lu.se/research/diabetes-islet-pathophysiology - 2025-05-23

Harry Björkbacka’s group Cardiovascular disease is the number one cause of death in people living with diabetes, and people with diabetes are twice as likely to have heart disease or suffer a stroke than people without diabetes. Cardiovascular disease is mainly caused by atherosclerosis, which is characterized by lipid deposition, chronic inflammation, immune cell accumulation, and fibrosis of the

https://www.ludc.lu.se/research/experimental-cardiovascular-research - 2025-05-23

Lund University Diabetes Centre is home to about 30 research groups. Our scientists look for new treatments and drugs to prevent, delay, or cure diabetes. The research teams also work towards developing personalised care and treatment for patients with diabetes.  Daniel Agardh's group Anna Blom's group João Duarte’s group Isabel Goncalves' group Philipp Kaldis’ group Marju Orho-Melander’s group Pe

https://www.ludc.lu.se/research - 2025-05-23

Leaders for work package 2: Charlotte Ling and Hindrik Mulder This work package (WP2) will take advantage of the large observational cohorts with corresponding samples and will use cutting edge technology for the discovery and validation of new genetic and non-genetic biomarkers. WP2 will also use established tools for the validation of biomarker candidates recently identified by LUDC investigator

https://www.ludc.lu.se/ludc-irc/biomarker-discovery-observational-prospective-studies - 2025-05-23

Lund University Diabetes Centre (LUDC) is a research centre dedicated to unravelling the mechanisms behind diabetes and its complications. Our vision at LUDC is to improve patient stratification and to undertake innovative translational studies that lead to better prevention and management of diabetes and its complications through precision diabetes medicine.At LUDC, more than 300 people work in a

https://www.ludc.lu.se/ludc - 2025-05-23

Researchers at LUDC are part of EXODIAB (Excellence of Diabetes Research in Sweden), a strategic research area at Lund University. The aim of EXODIAB is to develop new treatments and drugs to prevent or cure diabetes. The primary aim of EXODIAB is to develop new treatments and drugs that can prevent, delay, or cure diabetes and its complications. A second objective is to create improved conditions

https://www.ludc.lu.se/ludc/exodiab-strategic-research - 2025-05-23

Lund University Diabetes Centre (LUDC) is one of the largest diabetes research centres in the world with more than 300 members of staff. LUDC is working towards improved diagnosis, prevention, and treatment of diabetes and combines expertise in several fields to achieve this goal.The research centre gathers expertise in genetics, epidemiology, statistics, bioinformatics, molecular and cellular bio

https://www.ludc.lu.se/ludc/work-ludc - 2025-05-23