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Purpose: PFAPA syndrome is a benign, recurrent inflammatory disease of childhood. Tonsillectomy is one of the therapeutic options with a yet unexplained biological mechanism. We tested whether specific lymphocyte subsets recruited from blood to human tonsils participate in PFAPA pathogenesis. Methods: Paired tonsils/peripheral blood (PB) samples were investigated (a) from children with PFAPA that
While many pathways to post-fossil futures have been articulated, most fail to engage people in imagining themselves as being part of those futures and involved in the transition. Following recent calls for more immersive experiences, the 2019 initiative “Carbon Ruins—An Exhibition of the Fossil Era” (Carbon Ruins) is a performance set around a historical museum from the future, which uses recogni
Chronic granulomatous disease (CGD) can be cured by allogeneic hemopoietic stem cell transplantation (HSCT). Complications include graft failure, graft-versus-host disease (GVHD), infection, and transplant-related mortality; therefore, reduced-intensity conditioning regimens are being used to improve outcomes. In this retrospective study, the aim was to determine the outcome of treosulfan-based co
This article investigates the political attempts to frame European climate politics and provides a critical discourse analysis of the European Green Deal. A rapid transition towards low-carbon development across the world has been contested by discourses aiming to acknowledge the inseparability of social and ecological issues. These discussions are fairly new in the European context and in 2019, t
The existing information supports the use of this material as described in this safety assessment. 6-Nonenenitrile, (Z)- (9CI) was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from read-across analog 3-(cis-3-hexenyloxy)propanenitrile (CAS # 142653-61-0) sh
Mantle cell lymphoma (MCL) is an incurable disease with a highly variable clinical course. The prognosis after relapse is generally poor, and no standard of care exists. We investigated the postrelapse outcomes of 149 patients who were initially treated in the Nordic Lymphoma Group trials, MCL2 or MCL3, both representing intensive cytarabine-containing frontline regimens including autologous stem
Purpose: The COVID-19 pandemic brought unprecedented conditions for overall health care systems by restricting resources for non-COVID-19 patients. As the burden of the disease escalates, routine elective surgeries are being cancelled. The aim of this paper was to provide a guideline for management of endocrine surgical disorders during a pandemic. Methods: We used Delphi method with a nine-scale
Experimental methods to study the breakup frequency in industrial devices are increasingly important. Since industrial production-scale devices are often inaccessible to single-drop experiments, breakup frequencies for these devices can only be studied with “global methods”; i.e., breakup frequency estimated from analyzing emulsification-experiment data. However, how much can be said about th
BACKGROUND: The "Managing Fatigue" (MF) programme can help people living with Multiple sclerosis (MS) manage fatigue in their everyday lives. The programme has been proven feasible with Swedish occupational therapists, but there is a lack of knowledge of how MS participants experience the programme, and what they learned from participating in the programme.AIM: To describe how Swedish MS participa
Johan Anselmsson och Burak Tunca på Ekonomihögskolan vid Lunds universitet har i samarbete med undersökningsföretaget Norstat en vecka efter Amazons lansering i Sverige gjort en uppföljning av vad som hänt sedan en liknande mätning gjordes i september, men då i samband med att spekulationer om Amazons intåg i Sverige tog fart.
Denna artikel bygger på aktuell internationell forskning samt en webbaserad enkätundersökning i ett samarbete mellan Ekonomihögskolan vid Lunds universitet och intervjuföretaget Norstat.
The global antimicrobial drug resistance crisis requires urgency in searching for more effective broad-spectrum antimicrobial drugs. Here, we present a complete circular genome sequence and a plasmid of an antimicrobial-producing isolate, Bacillus velezensis strain Sam8H1, from the Makgadikgadi saltpans in Botswana. Bioinformatic analyses revealed 12 putative secondary metabolite biosynthetic gene
Recent studies of beetle specimens deposited in collections have revealed five species new to the Swedish fauna to be hiding amongst their closely related species. In some cases, the species known to the Swedish fauna are widespread and considered common, making it easy to overlook the slight differences that separate them from the similar and less common species. Some of these species are restric
This article analyses the long-term development of social class differences in infant and child mortality in an area of southern Sweden, spanning from the early stages of the mortality transition at the beginning of the nineteenth century, to the late 1960s when both infant and child mortality had reached very low levels. Our findings show that infant and child mortality was fairly equal at the be
ObjectiveWe investigate the association between the geographic proximity of the grandparents on net marital fertility and maternal survival in Sweden, 1900–1910, within the framework of the cooperative-breeding-hypothesis.MethodsData were derived from Swedish full-count censuses (1880–1910) and the Swedish Death Index. Married couples were linked to their parental households. Poisson and logistic
A wide range of medical examinations are using analysis of images from different types of equipment. Using artificial intelligence, the assessments could be done automatically. This can have multiple benefits for the healthcare; reduce workload for medical doctors, decrease variations in diagnoses and cut waiting times for the patient as well as improve the performance. The aim of this thesis has
