Investigation of endoplasmic reticulum stress in response to hypoxia in lung fibroblasts
Lack of oxygen delivery to the cells results in excessive production of oxygen free radicals in the cells leading to a pathological condition postulated as hypoxia. One of the most crucial transcription factors that can adapt to the fluctuating levels of hypoxia is Hypoxia Inducible Factor-1α (HIF-1α). Chronic obstructive pulmonary disease (COPD) is amongst the common lung diseases majorly caused