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Baeyer-Villiger monooxygenases (BVMOs) are valuable enzymes for specific oxyfunctionalization chemistry. They catalyze the oxidation of ketones to esters, but are also capable of oxidizing other chemical functions, namely aldehydes and heteroatoms such as sulfur, nitrogen, selenium and boron. The oxidation specificity and enantioselectivity of a newly characterized BVMO (BVMO4) from a strain of Di
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Aims: To assess, by systematic review of the literature, (1) the prevalence and incidence of temporomandibular disorder (TMD) pain after whiplash trauma, and (2) whether treatment modalities commonly used for TMD are equally effective in patients with solely TMD pain and those with TMD/whiplash-associated disorders (WAD) pain. Methods: A systematic literature search of the PubMed, Cochrane Library
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In the current project, a finite element model is developed to analyse the long-term behaviour of timber beams. The time-dependent response of wood subjected to bending and moisture changes is investigated in terms of strains and stresses. A rheological model is implemented to capture the effects of creep, mechano-sorption and hygroexpansion. The model is validated against test results from Bengts
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It is generally recognised that agricultural intensification has lead to simplification of landscape structure, but it has not been clarified if this is a ubiquitous relationship. That is, it has been an open question whether agricultural intensity and landscape simplicity should be regarded as one single or as two separate dimensions. To evaluate this we analysed landscape data in 136 different 1
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A delayed rectifier voltage-gated K+ channel (Kv) represents the largest ionic conductance of platelets and megakaryocytes, but is undefined at the molecular level. Quantitative RT-PCR of all known Kv alpha and ancillary subunits showed that only Kv1.3 (KCNA3) is substantially expressed in human platelets. Furthermore, megakaryocytes from Kv1.3-/- mice or from wild-type mice exposed to the Kv1.3 b
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We report on the magnetization depth profile of a hybrid exchange-spring system in which a Co/Pd multilayer with perpendicular anisotropy is coupled to a CoFeB thin film with in-plane anisotropy. The competition between these two orthogonal anisotropies promotes a strong depth dependence of the magnetization orientation. The angle of the magnetization vector is sensitive both to the strength of th
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Truncating germline mutations in the tumor suppressor gene BRCA-1 associated protein-1 (BAP1) have been reported in families predisposed to developing a wide range of different cancer types including uveal melanoma and cutaneous melanoma. There has also been an association between amelanotic tumor development and germline BAP1 mutation suggesting a possible phenotypic characteristic of BAP1 mutati
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A novel rapid methodology for determining the chemical oxygen demand (COD) based on a thermal sensor with a flow injection analysis system was proposed and experimentally validated. The ability of this sensor to detect and monitor COD was based on the degree of enthalpy increase when sodium hypochlorite reacted with the organic content in water samples. The measurement results were correlated with
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Objective. The aim of this study was to determine the prevalence of moderate ischemic mitral regurgitation (IMR) in the contemporary CABG population. We also aimed to correlate the effective regurgitant orifice area (ERO) of any regurgitant mitral valve in patients with coronary artery disease with the semiquantitative integrated scale of IMR. Design. From March 15 through June 15, 2006, 510 conse
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Abstract in UndeterminedTranslational stem cell research raises many interesting ethical questions, which have, to a greater or lesser degree, been debated at an international as well as at an interdisciplinary level. Nevertheless, there is still no international consensus regarding how a number of ethical questions related to this research should be answered. Many of these ethical questions creat
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We show how radiological images of both single and multi material samples can be simulated using the Monte Carlo simulation tool McXtrace and how these images can be used to make a three dimensional reconstruction. Good numerical agreement between the X-ray attenuation coefficient in experimental and simulated data can be obtained, which allows us to use simulated projections in the linearisation
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By mimicking embryonic development of the hematopoietic system, we have developed an optimized in vitro differentiation protocol for the generation of precursors of hematopoietic lineages and primitive hematopoietic cells from human embryonic stem cells (ES) and induced pluripotent stem cells (iPS). Factors such as cytokines, extra cellular matrix components, and small molecules, as well as the te
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The title compound, cis-[Pt(CH3COO)2(C2H6S)2], crystallizes in the P21/c space group with a pseudo-square-planar geometry. The complex forms centrosymmetric dimeric packing units, with C-H...O-Pt interactions and a short Pt...Pt distance [3.5868(2) Å]. The coordination mode of the acetate ligands is monodentate and they are oriented almost perpendicular to the coordination plane. Cambridge Structu
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Consider the communication system model y = HFx+n, where H and F are the channel and precoder matrices, x is a vector of data symbols drawn from some lattice-type constellation, such as M-QAM, n is an additive white Gaussian noise vector and y is the received vector. It is assumed that both the transmitter and the receiver have perfect knowledge of the channel matrix H and that the transmitted sig
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Using the information of the microstructure, this paper presents the development of an incremental constitutive law governing the response of an electro-magneto-thermo-mechanical smart composite. In this development, different shapes of reinforcements that have magneto-electro-thermo-elastic properties that differ from the matrix material are considered. Shapes such as ellipsoidal (spherical, prol
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Här jämförs författaren Axel Wallengren (Falstaff, fakir) med några kvinnliga skribenter: Anna Myrberg (Svarta Masken), Klara Johanson, Harriet Löwenhjelm och Astrid Lindgren. Stilistisk släktskap och personliga beröringspunkter ger nya perspektiv på Wallengrens särdrag.
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We investigate various mechanisms contributing to the surface ion distributions in simple and mixed aqueous alkali-halide solutions depending on the total salt concentration, using a combination of photoelectron spectroscopy and molecular dynamics simulations. In simple solutions, the surface enhancement of large polarizable anions is reduced with increasing concentration. In the case of a NaBr/Na
