We have analyzed the M-bcr breakpoint position in 133 Philadelphia-positive chronic myeloid leukemia patients and correlated the findings with clinical, hematologic, and cytogenetic data. We also investigated the splicing pattern of the BCR-ABL mRNA in 30 patients, using reverse transcriptase PCR. No statistically significant differences were found between breakpoint position within M-bcr and clin

alpha-Cells were identified in preparations of dispersed mouse islets by immunofluorescence microscopy. A high fraction of alpha-cells correlated with a small cell size measured as the average cell diameter (10 microm) and whole-cell capacitance (

Theoretical oscillator strengths for transitions between the even 4s(2) 4p(2) and the three odd {4s4p(3), 4s(2)4p4d, 4s(2)4p5s} configurations of As+ are reported. Both ab initio, multiconfiguration Hartree-Fock and semiempirical configuration interaction techniques are used. The uncertainty of the results are estimated, by considering the reproduced energy structure, the agreement of results from

Popular Abstract in Swedish Parkinsons sjukdom beror på att de dopamin-producerande cellerna i hjärnan dör. Detta leder till minskad rörlighet, svårigheter i att påbörja och avsluta en rörelse, balanssvårigheter och darrningar (tremor) hos de drabbade patienterna. Varför dopamincellerna dör är oklart och i nulägat kan man inte bota Parkinsons sjukdom, men man kan lindra symptomen med mediciner. PaParkinson's disease (PD) is a neurodegenerative disorder where the midbrain dopaminergic neurons are lost. Presently there is no cure for PD, and the most common treatment is to replace the lost dopamine pharmacologically by administration of the dopamine precursor L-DOPA. This works very well during the initial treatment period, but unfortunately a majority of the patients develop abnormal involu

AIM: The purpose of the study was to explore the effects of using a structured nursing intervention programme in hypertension care. BACKGROUND: Counselling on lifestyle changes to address hypertension helps patients reduce risk factors such as smoking, high alcohol consumption, overweight, dyslipidemia, negative stress and physical inactivity. DESIGN: The study was performed as a pre-test-post-tes

An evolutionary game of individuals cooperating to obtain a collective benefit is here modelled as an n-player Prisoner's Dilemma game. With reference to biological situations, such as group foraging, we introduce a threshold condition in the number of cooperators required to obtain the collective benefit. In the simplest version, a three-player game, complex behaviour appears as the replicator dy

Popular Abstract in Swedish Det mystika arvet: om konsten att erhålla och förklara det (och förstå litegrann): Ett turkiskt exempel.Mystics and amateur politicians in the margin of Turkish society. The specific case of marginalisation in the specific context of my choice provides a wealth of details to be accounted for. All details taken together are real life itself and can thus not be accounted for in a book. Enough can be said, however, about marginalisation in general in order for a meaningful discussion to take place. Bu

We present approximations of varying degree of sophistication to the integral equations for the (gluon) structure functions of a hadron ("the partonic flux factor") in a model valid in the leading log approximation with a running coupling constant. The results are all of the BFKL type, i.e., a power in the Bjorken variable x(B)(-lambda) with the parameter lambda determined from the size alpha(0) o

Background: Two heterologous pathways have been used to construct recombinant xylose-fermenting Saccharomyces cerevisiae strains: i) the xylose reductase ( XR) and xylitol dehydrogenase (XDH) pathway and ii) the xylose isomerase (XI) pathway. In the present study, the Pichia stipitis XR-XDH pathway and the Piromyces XI pathway were compared in an isogenic strain background, using a laboratory host

Earlier studies have demonstrated an important role for the chemokine CCL25, and its receptor CCR9, in the generation of the small intestinal lymphocyte compartment. The work in this thesis was aimed at determining how CCL25 is regulated within the small intestinal mucosa, and what potential role it plays in T cell localization to and function within this site. We have identified epithelial cells

High intakes of alcohol have adverse effects on skeletal health, but evidence for the effects of moderate consumption are less secure. The aim of this study was to quantify this risk on an international basis and explore the relationship of this risk with age, sex, and bone mineral density (BMD). We studied 5,939 men and 11,032 women from three prospectively studied cohorts comprising CaMos, DOES,

In this report, the measured adsorption isotherms on porous glass, obtained experimentally at different temperatures, are used to calculate the specific surface area, using two different types of BET-equations.

We introduce two novel joint radio-frequency (RF)-baseband designs for receivers in a MIMO system with Nt transmit antennas, Nr receive antennas, but only L < Nr RF chains at the receiver. The joint design introduces an RF pre-processing matrix that processes the signals from the different antennas, and is followed by selection (if necessary), down-conversion, and further processing in the baseban

SASE saturation was recently achieved at the Advanced Photon Source's SASE FFL in the low-energy undulator test line at 530 nm and 385 urn. The electron beam microbunching becomes more and more prominent until saturation is achieved. This bunching causes nonlinear harmonic emission that extends the usefulness of a SASE system in achieving shorter FEL wavelengths for the same electron beam energy.

We assessed a total range of peripheral thyroid hormone fractions, binding globulins, and thyroid-active antibodies in 37 medication-free, violent or sexual offenders, aged 17-45 years, to describe possible mechanisms involved in the thyroid metabolism of aggressive men. The ratio between T3 and T4 correlated with ratings of psychopathy, indicating increased peripheral deiodination as a biological