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Surgical approach, relapse risk and overall survival in borderline ovarian tumors: age-stratified analysis based on real-world data

Background: The need for complete staging surgery including hysterectomy for all age patients with borderline ovarian tumors (BOT) is debatable, considering fertility in younger patients and potential higher morbidity in older patients. We aimed to investigate the relapse risk and overall survival in a cohort including patients who underwent conservative surgery (organ-preserving procedures) to miBackground:The need for complete staging surgery including hysterectomy for all age patients with borderline ovarian tumors (BOT) is debatable, considering fertility in younger patients and potential higher morbidity in older patients. We aimed to investigate the relapse risk and overall survival in a cohort including patients who underwent conservative surgery (organ-preserving procedures) to min

Search for electroweak-scale dijet resonances using trigger-level analysis with the ATLAS detector in 132 fb-1 of pp collisions at √s = 13 TeV

This article reports on a search for dijet resonances using 132 fb−1 of pp collision data recorded at (Formula presented) ¼ 13 TeV by the ATLAS detector at the Large Hadron Collider. The search is performed solely on jets reconstructed within the ATLAS trigger to overcome bandwidth limitations imposed on conventional single-jet triggers, which would otherwise reject data from decays of sub-TeV dij

Kustlinjeutveckling vid Ystad Sandskogs västra strand: Modellering i ShorelineS med fokus på kustparallell sedimenttransport och kusterosion

I följande examensarbete undersöks den morfologiska kustlinjeutvecklingen vid den västra stranden i Ystad Sandskog med fokus på kusterosion och längsgående sedimenttransport. Kuststräckan är historiskt och fortsatt erosionsutsatt och ligger i nära anslutning till bebyggelser, infrastruktur och naturreservatet Sandskogen. För att motverka kustens tillbakadragning har flera kustskyddsåtgärder implemThis master thesis investigates the morphological shoreline development at the western beach of Ystad Sandskog, with a focus on coastal erosion and longshore sediment transport. The coastline is affected by erosion and is located close to residential areas, infrastructure and the nature preserve Sandskogen. Several coastal protection measures have been implemented to prevent ongoing shoreline retr

Threats and protection of on-chip test features throughout the lifetime of Integrated Circuits

The development and manufacturing process for Integrated Circuits (ICs) has become complex and globally distributed. System integrators use a mix of custom made logic with third-party Intellectual Property (IP) blocks, untrusted software tools, and external actors for manufacturing, post-production test, and validation. The many untrusted actors involved throughout the IC’s lifetime become a secur

Streets as platforms of public life

Streets are emerging as vibrant platforms of public life. While mobility continues to be the dominant function of these spaces, streets are being reconfigured by various stakeholders to promote multifunctional benefits, including socialisation and inclusion, play and rest, political action, economic opportunities, biodiversity, and cultural expression. This thematic issue includes a wide range of

The influence of relative humidity on rhinovirus infectivity in the aerosol phase

Introduction: The recent Covid-19 pandemic has renewed interest in studying the impact of environmental factors on the airborne transmission of viral infectious diseases. Human rhinovirus is the main cause of acute respiratory infections, primarily driven by young children who have an average of 6 -10 infections annually, while healthy adults typically experience 2–3 infections per year. Although

Designing Future Smart Battery Enclosures

Elsparkcyklarna sprider sig, inte bara inom Lund utan över hela jorden. Därför växer även behovet av säkrare och mer hållbara batterier. Batteriets hölje är särskilt kritiskt för att skydda batteriet mot stötar, värme och elektromagnetism. Detta examensarbete fokuserade på just detta hölje och om det är rimligt att 3D-printa det. Genom ett omfattande designprojekt mynnade arbetet slutligen ut i koThe aim of this project was to explore battery enclosures, specifically for e-scooter batteries, and whether additive manufacturing can be used to enhance existing designs. Furthermore, FEM and topology optimization were explored as tools for optimizing these designs. A modified Double Diamond approach was used as a guideline for the project. The modified version enters a prolonged optimization p

How Low Can You Go? Investigating Frame Rate Requirements for Pediatric Cardiovascular Surgery

Vad händer med den kirurgiska förmågan när man sänker bildfrekvensen? En studie för utveckling av autonoma kirurgiska robotar med människan som utgångspunkt. Varje år föds cirka 1.3 miljoner barn med hjärtfel och cirka 25% behöver vård inom ett år för att överleva. Då det råder global brist på barnhjärtkirurger, hinner inte alla barn få den vård de behöver. Det kan dessutom ta en kirurg 15-20 år A shortage of pediatric heart surgeons across the world limits the available surgical interventions, leading to long wait times and higher risk of mortality. The use of robotic surgery and its advantages may help address this issue, and the Collaborative Articial Intelligence Sur- gical Assistance-project is a starting point to develop an autonomous robotic surgical assistant. However, the video f

LAS24 Material Explorations

As the green transition requires a radical approach to the re/distribution of resources, the 2024 edition of Lund Architecture Symposium (LAS24) invites a cohort of progressive architectural practices to explore contemporary tendencies in space and materiality. While the construction industry accounts for nearly 40% of the global CO2 footprint – much coming from the production and waste of materia

LAS23 Celebrating Architecture: Øresund in the contemporary : Lund Architecture Symposium 2023

2023 marks the year when the UIA World Congress Copenhagen event turns the Øresund Region into the epicenter of global debate on architecture’s capacity to reimagine the transformation of societies into sustainable living. Celebrating this manifestation, which will commence on both sides of the Sound, LAS23 will utilize the New European Bauhaus’ three concepts -- sustainability, aesthetics, inclus

Pancreatic steatosis is a risk factor for pancreatic cysts among patients with diabetes

Objectives: To investigate whether pancreatic steatosis is associated with the presence of pancreatic cysts among individuals with diabetes. Material and Methods: 158 individuals [mean age 66 ± 10 years, 81 (51%) female] with diabetes [135 (85%) had type 2 diabetes] participated in the study involving Magnetic Resonance Imaging (MRI), blood tests and anthropometric measurements. Pancreatic steatos

Seconds after aerosolisation : the impact of relative humidity on airborne influenza virus

Influenza A virus (IAV) is a major respiratory pathogen, causing around 650,000 deaths annually. Asignificant transmission pathway for IAV is via expelled respiratory aerosol. For successfultransmission via the aerosol route, IAV must remain infectious following transport from an infectedhost to a susceptible individual. Many environmental factors may affect IAV infectivity, includingambient relat

Environmental enrichment modulates chronic poststroke inflammation and links white matter TREM2-positive microglia in recovery in mice

Background: Environmental enrichment (EE) has been widely reported to improve functional recovery after stroke, yet its effects on chronic inflammation and white matter pathology remain less well defined. The aim of this study was to investigate whether poststroke EE modulates chronic neuroinflammation and white matter pathology and how these changes relate to functional recovery. Methods: Here, w

Better reporting is better science : Community-defined minimal reporting requirements for light microscopy

Incomplete reporting of microscopy methods undermines transparency, reproducibility, and data reuse. Despite recent initiatives, comprehensive, broadly endorsed, and accessible reporting guidelines are still lacking. Here, we present a bare minimal microscopy reporting requirements checklist that integrates human- and machine-readable input to provide clear, actionable guidance for researchers, re

The cloud has wires : Toward circular governance of smart grids

Smart grids are widely promoted as efficient, low-carbon solutions for energy transitions, yet their governance often treats digital infrastructure as immaterial and uniformly beneficial. This obscures the material, temporal, and justice dimensions that shape real-world outcomes. We introduce Circular Grid Governance (CGG), a framework that integrates circular-economy principles, lifecycle thinkin

Protocol for efficient CRISPRi-mediated silencing of retrotransposons in human pluripotent stem cells

Here, we present a workflow for transcriptional silencing of transposable elements (TEs) in human induced pluripotent stem cells (hiPSCs). We describe steps for designing guide RNAs (gRNAs) to target TE families or unique TE loci. We also detail procedures for validating the efficiency and specificity of large-scale CRISPRi-based silencing using a multiome approach combining bulk RNA sequencing, C

Towards a Standard Protocol for Fecal Microbiota Transplantation in Irritable Bowel Syndrome

Randomized controlled trials (RCTs) of fecal microbiota transplantation (FMT) in patients with irritable bowel syndrome (IBS) have produced outcomes varying from no effect at all to high efficacy and durable effects over time. This review analyzed differences in the protocols used in FMT RCTs for IBS in the recently published literature with the aim of identifying the factors responsible for the s