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Increased metabolism in the R6/2 mouse model of Huntington's disease

van der Burg JMM, Bacos K, Wood N, Lindqvist A, Wierup N, Wamsteeker J, Deierborg-Olsson T, Mulder H, Erlanson-Albertsson C, Morton J, Brundin P, Björkqvist M* and Petersén Å*.Neurobiology of Disease 29: 41-51 (2008) *equal contribution AbstractHuntington's disease (HD) is a hereditary disorder characterized by personality changes, chorea, dementia and weight loss. The cause of this weight loss is

https://www.huntington-research.lu.se/increased-metabolism-r62-mouse-model-huntingtons-disease - 2026-04-23

Proteomic profiling of plasma in Hungtinton's disease reveals neuroinflammatory acivation and biomarker candidates

Dalrymple A, Wild E, Joubert R, Sathasivam K, Björkqvist M, Petersén Å, Isaacs J, Kristiansten M, Bates G, Leavitt B, Keir G, Ward M and Tabrizi SJ.Journal of Proteome Research 6: 2833-2840 (2007)AbstractHuntington's disease (HD) causes widespread CNS changes and systemic abnormalities including endocrine and immune dysfunction. HD biomarkers are needed to power clinical trials of potential treatm

https://www.huntington-research.lu.se/proteomic-profiling-plasma-hungtintons-disease-reveals-neuroinflammatory-acivation-and-biomarker - 2026-04-23

Orexin and psychiatric symptoms in suicide attempters

Brundin L, Petersén Å, Björkqvist M and Träskman-Bendz L.Journal of Affective Disorders 100: 259-263 (2007)AbstractBACKGROUND:The orexins (hypocretins) are recently discovered hypothalamic peptides that are involved in the regulation of sleep, appetite and state of arousal. In the present study, we investigated the relationship between cerebrospinal fluid (CSF) orexin and specific psychiatric symp

https://www.huntington-research.lu.se/orexin-and-psychiatric-symptoms-suicide-attempters - 2026-04-23

Cocaine- and amphetamine-regulated transcript is increased in Huntington disease

Björkqvist M, Leavitt B, Nielsen J, Landwehrmeyer B, Ecker D, Mulder H, Brundin P and Petersén Å.Movement Disorders 22: 1952-1954 (2007)AbstractWeight loss and anxiety frequently occur in individuals with Huntington's disease (HD) but the underlying mechanisms are not well-understood. Peptides produced in the hypothalamus are involved in regulating energy homeostasis and emotion. Recent data sugge

https://www.huntington-research.lu.se/cocaine-and-amphetamine-regulated-transcript-increased-huntington-disease - 2026-04-23

Reduced orexin levels in the cerebrospinal fluid of suicidal patients with major depressive disorder

Brundin L, Björkqvist M, Petersén Å and Träskman-Bendz L.European Neuropsychopharmacology 17: 573-579 (2007)AbstractOrexins are neuropeptides selectively expressed in a small number of neurons in the lateral-posterior hypothalamus. We measured orexin-A in the cerebrospinal fluid (CSF) of 66 patients with major depressive disorder (MDD), dysthymia and adjustment disorder after a suicide attempt. Bl

https://www.huntington-research.lu.se/reduced-orexin-levels-cerebrospinal-fluid-suicidal-patients-major-depressive-disorder - 2026-04-23

Testicular degeneration in Huntington disease

Van Raamsdonk JM, Murphy Z, Selva DM, Hamidizadeh R, Pearson J, Petersen Å, Björkqvist M, Muir C, Mackenzie IR, Hammond GL, Vogl AW, Hayden MR and Leavitt BR.Neurobiology of Disease 26: 512-520 (2007)AbstractHuntington disease (HD) is an adult onset, neurodegenerative disorder that results from CAG expansion in the HD gene. Recent work has demonstrated testicular degeneration in mouse models of HD

https://www.huntington-research.lu.se/testicular-degeneration-huntington-disease - 2026-04-23

Hypothalamic-endocrine aspects in Huntington’s disease

Petersén Å and Björkqvist M.European Journal of Neuroscience 24: 961-967 (2006)AbstractHuntington's disease (HD) is a hereditary and fatal disorder caused by an expanded CAG triplet repeat in the HD gene, resulting in a mutant form of the protein huntingtin. Wild-type and mutant huntingtin are expressed in most tissues of the body but the normal function of huntingtin is not fully known. In HD, th

https://www.huntington-research.lu.se/hypothalamic-endocrine-aspects-huntingtons-disease - 2026-04-23

Quantification of Total and Mutant Huntingtin Protein Levels in Biospecimens Using a Novel alphaLISA Assay

Baldo B, Sajjad MU, Cheong RY, Bigarreau J, Vijayvargia R, McLean C, Perrier AL, Seong IS, Halliday G, Petersén Å and Kirik D.ENeuro 5 (4). pii: ENEURO.0234-18.2018 (2018)AbstractThe neurodegenerative Huntington's disease (HD) is caused by a polyglutamine (polyQ) amplification in the huntingtin protein (HTT). Currently there is no effective therapy available for HD; however, several efforts are di

https://www.huntington-research.lu.se/quantification-total-and-mutant-huntingtin-protein-levels-biospecimens-using-novel-alphalisa-assay - 2026-04-23

startsida

What is the Graduate School in Asian Studies? Our PhD courses Mobility Annual retreat Sign up for our newsletter Calendar Link to RSS 5 June 2026 10:15 to 12:00 | Lecture/talk The Slow Revolution: Women’s Futures in China’s Late Meritocracy More events

https://www.graduateschoolasianstudies.lu.se/startsida - 2026-04-23

Digital Methods

20 and 21 March 2024. Two-day workshop at Centre for East and South-East Asian Studies, Lund University Digital sources and methods are of increasing interest to Asian Studies researchers, but how can we best use these methods? Join us at the Centre for a two-day workshop on digital methods in Asian Studies organised by the Graduate School in Asian Studies. The workshop, envisioned as a meeting be

https://www.graduateschoolasianstudies.lu.se/activities/workshops/previous-workshops/digital-methods - 2026-04-23

Presentation Skills and Public Speaking

22 May, Stadshallen Lund At this workshop, led by Altitude Meetings, and co-organised with the Graduate School in History, you will get practical advice in a workshop format on how to become a better speaker. The workshop includes an inspiration lecture, advice on what is a good presentation, tips on body language and how to manage nervousness etc. The workshop also includes some practical exercis

https://www.graduateschoolasianstudies.lu.se/activities/workshops/previous-workshops/presentation-skills-and-public-speaking-0 - 2026-04-23

Contact us

People Lund office Programme Committee Advisory Board PhD students Postal address Lund University Graduate School in Asian Studies Centre for East and South-East Asian Studies P.O Box 118 SE- 221 00 Lund Sweden Visiting and delivery address Sölvegatan 18 B 223 62 Lund Sweden Google map  

https://www.graduateschoolasianstudies.lu.se/contact-us - 2026-04-23

Organization

The Graduate School in Asian Studies is coordinated and administered by the Centre for East and South-East Asian Studies at Lund University. It has a programme committee consisting of representatives from the different Swedish partner institutions who are involved in the planning and oversight of the school’s activities.  The graduate school also has an international advisory board with representa

https://www.graduateschoolasianstudies.lu.se/about-graduate-school-asian-studies/organization - 2026-04-23

PhD workshop on International Relations

The Graduate School in Asian Studies in cooperation with Horizon Europe EUVIP project (EU in the Volatile Indo-Pacific) invite you to apply for our PhD workshop on International Relations. The workshop will bring together PhD students and senior scholars working on Asian International Relations over two days here at the Centre for East and Southeast Asian Studies, to discuss key issues in the regi

https://www.graduateschoolasianstudies.lu.se/activities/workshops/previous-workshops/phd-workshop-international-relations - 2026-04-23

Podcast Production Workshop

As a partner for the Nordic Asia Podcast, the Centre/Graduate School is organizing a Podcast Production Workshop to provide practical training for participants to embark on the exciting journey into the world of podcasting. PhD candidate Joanne Kuai is an experienced journalist and podcaster producer and will be the instructor of the workshop. The venue will be the Centre for East and South-East A

https://www.graduateschoolasianstudies.lu.se/activities/workshops/previous-workshops/podcast-production-workshop - 2026-04-23