SUMMARY: When Efexor(R) (venlafaxine) became available in Sweden, a therapeutic drug monitoring (TDM) service was developed in the authors' laboratory. This analytical service was available to all physicians in the country. From March 1996, to November 1997, 797 serum concentration analyses of venlafaxine (VEN) and its main metabolites, O-desmethylvenlafaxine (ODV), N-desmethylvenlafaxine (NDV), a

Popular Abstract in Swedish I centrum för min avhandling står den spanske dominkanen Alonso de Montúfar (ca.1489-1572) som mellan 1554 och 1572 var ärkebiskop av Mexiko. I synnerhet har jag studerat hur ärkebiskop Montúfar ville att kyrkan skulle organiseras (hans kyrkovision) och hur han försökte förverkliga sin vision (hans kyrkopolitik). Montúfar kom till Mexiko drygt trettio år efter den spanThis dissertation focuses on Archbishop Alonso de Montúfar OP (ca. 1489-1572). It seeks to explore two decades of sixteenth century Mexican Church History mainly through the study of documents found in Spanish and Mexican archives. Born outside Granada in Southern Spain, just after the conquest from the Muslims, Alonso de Montúfar assumed teaching and leading positions within the Dominican order.

Two particle correlations between identified meson and baryon trigger particles with 2.5

The influence of improved diabetic control on peripheral nerve function was studied before and 3-4 months after institution of insulin treatment in 22 diabetics unsatisfactorily controlled by oral hypoglycemic agents. After institution of insulin treatment, diabetic control was improved as demonstrated by decreasing levels of HbA1. There was an overall tendency towards improvement of motor and sen

Objective Obstructive sleep apnoea (OSA) confers a risk of hypertension and cardiovascular complications. Both the renin-angiotensin-aldosterone system and OSA are important determinants of blood pressure, but it is not fully known how they interact. The aim of this study was to explore the interaction between the angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and O

We consider the lossy image compression problem and propose a model-residual approach. Polynomial basis images encode the model image and powerful new trellis codes quantize the residual part. A simple bit allocation scheme determines the residual bit rates and a variety of rates are attainable without entropy coding. The trellis structure is also used to form a joint source and channel coding sch

Den övergripande ambitionen i denna rapport är att sprida lärdomar och konkreta exempel på kommunal samverkan inom avfallssektorn. Konkret är det tre områden som står i fokus: • Att beskriva olika former av samverkan utifrån ett antal praktiska exempel. • Att analysera vilka typer av fördelar samverkan kan ge • Att beskriva hur parterna går tillväga när de samverkar, dvs samverkansprocessen. F

We have found a remarkable relationship between the specificity of antibodies and their chromatographic behavious upon liquid-liquid partition chromatography (LLPC). Well characterized human and murine monoclonal antibodies and Fab/Fv fragments thereof as well as mouse/human chimeric antibodies were employed. While, lgG 1, 2 and 4 antibodies with identical specificities (affinity constants) have i

An algal-bacterial consortium was tested for the treatment from a coke factory. A Chlorella vulgaris strain and a phenol-degrading Alcaligenes sp. were first isolated from the wastewater treatment plant to serve as inocula in the subsequent biodegradation tests. Batch tests were then conducted with samples from the real wastewater or using a synthetic wastewater containing 325 mg phenol/l and 500

Aseptic loosening of the tibial component is the major complication of total knee arthroplasty There is an association between early excessive shear micromotion between the bone and the tray of the tibial component and late aseptic loosening. Using non-linear finite element analysis, whether a tibial tray with a circumferentially flanged rim and a mating cut in the proximal tibia could minimize bo

Data taken with positrons of different longitudinal polarisation states in collision with unpolarised protons at HERA are used to measure the total cross sections of the charged current process, e(+) p -> nu X, for negative four-momentum transfer squared Q(2) > 400 GeV2 and inelasticity gamma < 0.9. Together with the corresponding cross section obtained from the previously published unpolarised da

Purpose: To evaluate the characteristics of polycystic compared to normal ovaries using three-dimensional (3-D) power Doppler ultrasonography. Methods: We recruited 42 volunteers, all of whom were commencing IVF treatment. Each patient was examined in the cycle preceeding the start of drug therapy during the late follicular phase. IF eight or more subcapsular follicles of 2-8 mm in diameter in one

Sweden is perceived to be top ranking. and a 'role model', in terms of its volume of academic R&D. This perception is based on analyses using two standard indicators. We assess the validity of these and argue that institutional features skew the result in favour of a high ranking. Swedish academic R&D is more appropriately characterised as average. or below average. in terms of input and a

We report karyotypic features of 106 short-term cultured oral squamous cell carcinomas (SCC), 51 new and 55 previously reported cases, with clonal chromosome aberrations. The major cytogenetic findings were as follows: simple karyotypic changes were present in 38 cases (36%) and 68 tumors (64%) displayed complex karyotypes. The most common numerical changes were +7, +8, +9, +16, +18, +20, and -4,

The contractile and relaxant effects of the different P2 receptors were characterized in the rat isolated mesenteric artery by use of extracellular nucleotides, including the stable pyrimidines uridine 5'-O-thiodiphosphate (UDPbetaS) and uridine 5'-O-3-thiotriphosphate (UTPgammaS). The selective P2X receptor agonist, alphabeta-methylene-adenosine triphosphate (alphabeta-MeATP) stimulated a potent