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Intestinal permeability in humans is increased after radiation therapy

PURPOSE: Irradiation inflicts acute injuries to the intestinal mucosa with rapid apoptosis induction and subsequent reduction in epithelial surface area. It may therefore be assumed that the intestinal barrier function is affected. The aim of this study was to compare the mucosal permeability in irradiated rectum and nonirradiated sigmoid colon from patients subjected to radiation therapy before s

Trends in the literature on eating disorders over 36 years (1965-2000): Terminology, interpretation and treatment

A database with more than 14 700 references to articles on ED during 1965-2000 was analysed with the aim of identifying long-term and short-term trends in the literature. The main data of the analysis are the percentages of references per 6-year period or per year for the most recent 6 years, that contain certain words or phrases. The use of words in references should reflect changes in the conten

Hibernomas are characterized by homozygous deletions in the multiple endocrine neoplasia type I region. Metaphase fluorescence in situ hybridization reveals complex rearrangements not detected by conventional cytogenetics

Hibernomas are benign tumors of brown fat, frequently characterized by aberrations of chromosome band 11q13. In this study, the chromosome 11 changes in five hibernomas were analyzed in detail by metaphase fluorescence in situ hybridization. In all cases, complex rearrangements leading to loss of chromosome 11 material were found. Deletions were present not only in those chromosomes that were show

Monitoring of friction processes by the means of acoustic emission measurements—deep drawing of sheet metal

Acoustic emission generated in deep drawing processes gives information about the friction and the forming processes between tool and workpiece. This information can be used to supervise or improve the forming process. Measurements of acoustic emission in manufacturing machines in production lines shows that different events such as, galling, tool wear, lubricating failure, different viscosity of

Determination of interstitial oxygen concentration in germanium by infrared absorption

The intensities of infrared absorption due to the asymmetric stretching vibrations of interstitial oxygen atoms in Ge crystals enriched with O-16 and O-18 isotopes have been compared with oxygen concentrations determined by means of secondary ion mass spectrometry. For Ge samples with oxygen content less than 5 x 10(17) cm(-3), a good correlation has been found between the values of oxygen concent

Influence of a drink containing different antioxidants and Lactobacillus plantarum 299v on plasma total antioxidant capacity, selenium status and faecal microbial flora

The aim of the study was to investigate whether a supplement of antioxidants to subjects with a high working pace can influence the antioxidant capacity. The study was parallel and double blind with 98 subjects randomised into two groups. One of the groups was given a test drink with antioxidants for 4 weeks (450 ml/day) while the other group took a corresponding amount of placebo drink. The test

Nurse-led heart failure follow-up in primary care in Sweden

Background: Little or no knowledge is available about which service is offered to patients with heart failure in primary care. Aims: To describe nurse-led follow-up of patients with heart failure in primary care in Sweden. Methods and results: A questionnaire was sent to all primary health care centres in Sweden and 6 10 of 939 centres returned the questionnaire. Special nurses had designated time

A randomized comparison of bypassing agents in hemophilia complicated by an inhibitor.

The development of inhibitory antibodies to factor VIII is a serious complication of hemophilia. FEIBA (factor VIII inhibitor-bypassing activity), an activated prothrombin complex concentrate (aPCC), and NovoSeven, recombinant factor Vila (rFVIIa), are used as hemostatic bypassing agents in treating patients with inhibitors. The FENOC study was designed to test equivalence of the products in the t

Zinc-alloys as tool materials in short-run sheet-metal forming processes - Experimental analysis of three different zinc-alloys

In recent years, there has been an increasing demand from manufacturing industries for new tool materials such as more wear resistant zinc-alloys, with optimised characteristics regarding short-run sheet-metal parts production. Research on zinc-alloys wear resistance has been performed by a lot of research groups. However, it is very difficult to compare the wear resistance of these materials due

Negative and positive regulatory epitopes in the C-terminal domains of the human B1 and B2 bradykinin receptor subtypes determine receptor coupling efficacy to G(q/11)-mediated [correction of G(9/11)-mediated] phospholipase Cbeta activity

The human B1 bradykinin (BK) receptor (B1R) is more efficacious than the human B2 BK receptor (B2R) in both ligand-independent and agonist-dependent coupling to Gq/11-mediated phospholipase Cbeta activity. In fact, B1R is constitutively active, whereas B2R exhibits little if any constitutive activity. To evaluate the role of the C-terminal domain in receptor Gq/11 coupling, we constructed chimeric

Calculations of interfacial interactions in pyrene-Ipa rod sensitized nanostructured TiO2

Pyrene chromophores carrying different rigid rod spacer groups (ethynylene, ethynylene-phenylene-ethynylene, and ethynylene-bicyclo[2.2.2]octylene-ethynylene) and bound to TiO2 nanostructured materials via an isophthalic acid (Ipa) anchor group have been investigated using quantum chemical calculations in order to elucidate structural and electronic properties of dye-sensitized semiconductor struc

Computation of conical intersections by using perturbation techniques

Multiconfigurational second-order perturbation theory, both in its single-state multiconfigurational second-order perturbation theory (CASPT2) and multistate (MS-CASPT2) formulations, is used to search for minima on the crossing seams between different potential energy hypersurfaces of electronic states in several molecular systems. The performance of the procedures is tested and discussed, focusi

Improvement of direct bioelectrocatalysis by cellobiose dehydrogenase on screen printed graphite electrodes using polyaniline modification

Modification of graphite based screen printed electrodes (SPEs) by electrosynthesised polyaniline (PANI) has been applied to improve the electron exchange between cellobiose dehydrogenase (CDH, EC 1.1.99.18) from the ascomycete Myriococcum thermophilum and the surface of the SPE. The redox intermediate layer of the conducting polymer promotes the bioelectrocatalysis providing a higher current for

Aspiration of dead space allows isocapnic low tidal volume ventilation in acute lung injury. Relationships to gas exchange and mechanics

OBJECTIVE: In acute lung injury (ALI) mechanical ventilation damages lungs. We hypothesised that aspiration and replacement of dead space during expiration (ASPIDS) allows normocapnic ventilation at higher end-expiratory pressure (PEEP) and reduced tidal volume (V(T)), peak and plateau pressures (Paw(peak), Paw(plat)), thus avoiding lung damage. SETTING: University Hospital. PATIENTS: Seven consec

Spatial Dynamics Methods for Solitary Gravity-Capillary Water Waves with an Arbitrary Distribution of Vorticity

This paper presents existence theories for several families of small-amplitude solitary-wave solutions to the classical two-dimensional water-wave problem in the presence of surface tension and with an arbitrary distribution of vorticity. Moreover, the established local bifurcation diagram for irrotational solitary waves is shown to remain qualitatively unchanged for any choice of vorticity distri