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The long-term culture of human embryonic stem (ES) cells is inevitably subject to evolution, since any mutant that arises with a growth advantage will be selectively amplified. However, the evolutionary influences of population size, mutation rate, and selection pressure are frequently overlooked. We have constructed a Monte Carlo simulation model to predict how changes in these factors can influe
The fundamentals of analyte extractable fraction, solubility, partitioning and mass transfer resistance in supercritical fluid extraction were studied using inverse modeling. These phenomena are essential for understanding, predicting and optimizing the supercritical fluid extraction process. Carotenoids, chlorophyll A, ergosterol and total lipids were extracted from the microalgae Chlorella sp. T
Two dolerite dyke swarms are recognized along and paralleling the Ural Mountains, Russia. The Uralian swarm is 1400-km long (2300-km long if traced from its inferred plume centre). Further north, the Pay-Khoy swarm can be traced through the Pay-Khoy–Novaya Zemlya fold belt for a distance of c. 250 km (800-km long if traced from its inferred plume centre). An Upper Devonian age for volcanism associ
A comparative study of the antioxidant activity of hydroxytyrosol (HT) and phosphatidyl derivatives of hydroxytyrosol (PHT) added at increasing concentrations to diverse edible oils (lard oil, refined olive oil, and diacylglycerol-rich oil) was performed. Antioxidant activity index was estimated as the ratio of induction time in presence of the compounds to induction time in their absence, after o
Depicting developmental processes as movements in free energy genetic landscapes is an illustrative tool. However, exploring such landscapes to obtain quantitative or even qualitative predictions is hampered by the lack of free energy functions corresponding to the biochemical Michaelis– Menten or Hill rate equations for the dynamics. Being armed with energy landscapes defined by a network and its
Background: The tuberculin skin test is used for tracing of tuberculosis transmission and identifying individuals in need of prophylactic treatment. Methods: Using a case-control study design, we recruited 220 smear-positive tuberculosis cases and 223 randomly selected healthy community controls in Bissau, Guinea-Bissau, during 1999-2000. Tuberculin skin tests were performed on family members of c
Studiens syfte var att analysera hur ledarskapsstrateger i Skånes näringsliv uppfattade effekterna av genomförda ledarskapsutbildningar. En riktad innehållsanalys användes. 16 personer (på 15 företag) i olika ledande positioner med inflytande över beställningsprocessen av ledarskapsutbildningar intervjuades. Studiens resultat visar att intervjupersonerna hade uppfattningen att ledarskapsutbildningThe purpose of the study was to analyze how ‘leadership strategists’ in Skåne's business community perceived the effects of leadership training. A directed content analysis was adopted. 16 people (from 15 companies) in various leadership positions with authority to influence the process of contracting for leadership training were interviewed. The results of this study shows that the interviewe
Syftet med examensarbetet är att undersöka hur fastighetsbildningen för jordbruksändamål kan anpassas till det moderna jordbruket. Nedan följer bakgrunden till mina förslag på anpassning av fastighetsbildningen till det moderna jordbruket: Jordbrukarna föredrar stora jordbruksfastigheter. Idag är det bara riktigt stora jordbruksfastigheter som anses skyddsvärda enligt 3 kap. 6 § FBL. Det är viktThe purpose of this master thesis is to examine how property formation for agricultural purposes can be accommodated to the modern-day agriculture. Agricultural holdings in the size ranges 15-30 and 30-100 hectares are declining rapidly in Sweden. It was common that agriculturalists in Helsingborg municipality that had an agricultural holding in the size range of 30-100 hectares had a hard time t
Shopping malls are becoming more prevalent throughout the world. They have been identified as having high energy use, which is less explored than other building types. There are 357 shopping centers in Sweden, which has doubled in the last five years. Regardless of national differences in shopping mall tenants' demands, shopping malls always tend to have high lighting loads, high population de
The climate impact of food production plays a big part in the anthropogenic climate impact. Mitigation strategies from this sector are hence of great importance. One area which mainly has been used to calculate climate impact is albedo, the overall reflectance of incoming radiation in all directions. Albedo has been measured for a long time and is vital when calculating the energy balance of an a
This thesis defines the finite projective plane and the affine projective plane. A method of construction is defined for the field planes by extension of the affine plane constructed from the vector space over a finite field. The thesis explores for which orders planes can and cannot be constructed, in particular, for the prime powers there exist planes. For n=6 a computer search is conducted usin
This thesis identifies and evaluates business model alternatives for Oceanbird’s Wing 560 rigid sail, a wind-assisted ship propulsion technology approaching broader commercialisation. The shipping industry’s complex ownership structures create split-incentive problems that complicate investment in fuel-saving technologies, making the choice of business model a strategic decision. Furthermore, the
Propionic acid (PA) production from agro-industrial residues using propionibacteria has gained interest as an alternative to fossil-based process. Microbial production is however characterized by product inhibition, lowering the product titers and productivity. In this study, Propionibacterium acidipropionici DSMZ4900 was subjected to adaptive evolution to tolerate higher acid concentrations. The
The present dissertation concerns typologically unusual ways of encoding manner information, namely verbal affixes (manner affixes), incorporated constituents (incorporated manner modifiers) and auxiliary verbs (manner adverbial verbs). A key proposal is that all three are overt realizations of syntactic heads merged in the clausal spine, thereby presenting novel data that can be used to probe int
There is no apparent need for individuals to endure this kind of suffering in contemporary Western society with all its advantages. Nevertheless, endurance running is now a mainstream leisure pursuit. Why do hundreds of thousands of men, women and even children choose this torturous kind of leisure activity?In previous literature on consumption of extraordinary experiences, authors focus on the pu
We investigate subalgebras of finite codimension in. In earlier work we have introduced a way of describing such subalgebras in terms of their so called (subalgebra) spectrum and a set of conditions for subalgebra membership that can be expressed by evaluating polynomials and their derivatives in points of the spectrum only. In this paper we focus on subalgebras with a single element in their spec
This thesis contributes to the understanding of sustainability-oriented technological innovation (SOTI) by applying an innovation ecosystem perspective. The aim is to explore how interactions between actors shape SOTI and how these interactions enable or constrain adoption in practice. To address this purpose, a qualitative case study was conducted within the Swedish agri-food innovation ecosystem
