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Synthesis of 14-oxa-1,4,8,11-tetraazabicyclo[9,5,3]nonadecane (L1) and a Spectroscopic and Structural Study of [Ni(L1)(ClO4)](ClO4) and of the Macrobicyclic Precursor Diamide Complex, [Ni(HL2)](ClO4); Chloride Substitution Kinetics of the Corresponding [Ni(III)(L1)]3+ Species

The pentadentate ligand 14-oxa-1,4,8,11-tetraazabicyclo[9.5.3]nonadecane (L1) has been synthesized by the high dilution cyclization of 1-oxa-4,8-diazacyclododecane ([10]aneN2O) (1) with 1,3-bis(α-chloroacetamido)propane (2) and subsequent reduction of the diamide intermediate. The structure [Ni(L1)(ClO4)](ClO4) (P21/c (no. 14), a = 8.608(3), b = 16.618(3), c = 14.924(4) Å, β = 91.53(3)° converged

Tumor necrosis factor (TNF) inhibitors for psoriatic arthritis

BackgroundPsoriatic arthritis (PsA) is a chronic arthritis affecting people with psoriasis. If untreated, it may lead to disability. Recommended drugs are non‐steroidal anti‐inflammatory drugs (NSAIDs), corticosteroids, conventional synthetic disease‐modifying anti‐rheumatic drugs (csDMARDs), biologic DMARDs (bDMARDs), and targeted synthetic DMARDs (tsDMARDs). Tumour necrosis factor inhibitors (TN

Proximal venous ultrasound with risk stratification safely excludes deep venous thrombosis in emergency department routine care : an observational study

Background: Lower limb deep vein thrombosis (DVT) is common in emergency departments (EDs) and can be fatal if left untreated due to the risk of progression to pulmonary embolism (PE). In Scandinavia, DVT diagnosis typically relies on ultrasound performed outside the ED in the diagnostic departments. However, international guidelines now recommend combining limited/proximal compression ultrasound

Binarity at LOw Metallicity (BLOeM): A spectroscopic VLT monitoring survey of massive stars in the SMC

Surveys in the Milky Way and Large Magellanic Cloud have revealed that the majority of massive stars will interact with companions during their lives. However, knowledge of the binary properties of massive stars at low metallicity, and therefore in conditions approaching those of the Early Universe, remain sparse. We present the Binarity at LOw Metallicity (BLOeM) campaign, an ESO large programme

Exploring Definitions and Predictors of Response to Biologics for Severe Asthma

Background: Biologic effectiveness is often assessed as response, a term that eludes consistent definition. Identifying those most likely to respond in real-life has proven challenging. Objective: To explore definitions of biologic responders in adults with severe asthma and investigate patient characteristics associated with biologic response. Methods: This was a longitudinal cohort study using d

Extended Swedish Adoption Study of Adverse Stress Responses and Posttraumatic Stress Disorder

IMPORTANCE Twin studies have found that posttraumatic stress disorder (PTSD) is influenced by both genetic and environmental factors within a generation. No study has used an adoption design, which can address questions about the degree and sources of cross-generational transmission of adverse stress responses (ASRs) and PTSD. OBJECTIVES To examine whether ASRs or PTSD are transmitted from parents

Embolization of percutaneous left atrial appendage closure devices: timing, management and clinical outcomes

Background: Left atrial appendage (LAA) occluder embolization is an infrequent but serious complication. Objectives: We aim to describe timing, management and clinical outcomes of device embolization in a multi-center registry. Methods: Patient characteristics, imaging findings and procedure and follow-up data were collected retrospectively. Device embolizations were categorized according to 1) ti

Homeownership While Aging-How Health and Economic Factors Incentivize or Disincentivize Relocation : Protocol for a Mixed Methods Project

BACKGROUND: Many factors influence housing choices among older adults, but far from all have been identified. There is little systematic analysis that has included economic factors and virtually no knowledge about the interplay among perceived costs of moving, health status, and the mobility rate of older homeowners. It is currently unclear whether economic factors influence older adults' willingn

Contributions of avoidable mortality to the sex gap in life expectancy and life disparity in Iran

BACKGROUND: Public health policies and healthcare quality play a pivotal role on the health outcome level and disparities across sociodemographic groups. However, there is little evidence on their role on disparities in life expectancy (LE) and life disparity (LD) in low and middle income countries. The present study aimed to assess the contributions of avoidable mortality, as a measure of inter-s

Seizure Duration and Electroconvulsive Therapy in Major Depressive Disorder

Importance: Electroconvulsive therapy (ECT), wherein a generalized epileptic seizure is induced, is a treatment for major depressive disorder (MDD). Currently, it is unclear whether there is an association between seizure length and treatment outcome. Objective: To explore the association between seizure duration, potential confounding variables, and ECT treatment outcome. Design, Setting, and Par

LSS och utlandsresor- Rättigheter och rättsdogmatik i konflikt?

I uppsatsen undersöks rättsläget gällande möjligheten att få hjälp med att resa utomlands för LSS målgrupp. Undersökningen utförs med hjälp av dels en rättsrealistisk rättsdogmatisk metod, dels med hjälp av en socialrättslig dogmatik. Slutsatsen blir att rätten till hjälp med semesterresor är förbehållen de med störst stödbehov och detta stödbehov måste vara konstant och det beskrivs inte rättsligIn this essay, the legal situation regarding the possibility of receiving assistance for traveling abroad, for the LSS (Law on Support and Service for Persons with Certain Functional Impairments) target group, is examined. The investigation is carried out using both a legal realist dogmatics method and a social legal dogmatics approach. The conclusion is that the right to assistance with vacation

Utbildningsplan För Masterprogrammet I Miljöstrategisk Styrning 20252026

Utbildningsplan för masterprogrammet i miljöstrategisk styrning/Master of Science in Environmental Management and Policy Programkod: XAMIS Omfattning: 120 HP Cykel: Andra Godkänd av: Godkänd av: programstyrelsen W Giltighet: 2025/2026 Datum för godkännande: 2025-02-10 Språk för undervisning: Engelska MÅL OCH RESULTAT 1.1 Syfte Det internationella masterprogrammet i miljöstrategisk styrning är utfo

https://www.iiiee.lu.se/sites/iiiee.lu.se/files/2025-09/Utbildningsplan%20fo%CC%88r%20masterprogrammet%20i%20miljo%CC%88strategisk%20styrning%2020252026.pdf - 2025-12-23

Sam Fak yttrande Grundläggande Fri Och Rättigheter SOU 2025-2

Lägg till titel Sida 1 av 5 Dekan REMISSYTTRANDE Diarienummer V 2025/205 Datum 2025-04-07 Yttrande för remissen: Några frågor om grundläggande fri- och rättigheter (SOU 2025:2) Samhällsvetenskapliga fakulteten vid Lunds universitet, som anmodats att yttra sig över rubricerade remiss, avger följande yttrande. Yttrandet har utarbetats av juris dr. och docent Jannice Käll, på Rättssociologiska instit

https://www.sam.lu.se/sites/sam.lu.se/files/2025-04/Sam_Fak_yttrande_Grundla%CC%88ggande%20fri%20och%20ra%CC%88ttigheter_SOU%202025-2.pdf - 2025-12-23

Emma Sparr, Professor

Emma Sparr, Professor | Division of Physical Chemistry Faculty of Science Search Division of Physical Chemistry Department of Chemistry Department of Chemistry Kemicentrum Safety and security Contact About Education Master/Bachelor-Projects News and events Research People Instruments COMMONS Center Center for Scattering Methods Home  >  People  >  Senior Scientists  >  Emma Sparr Denna sida på sve

https://www.physchem.lu.se/people/seniors/sparr/ - 2025-12-22

Emma Sparr, Professor

Emma Sparr, Professor | Division of Physical Chemistry Faculty of Science Search Division of Physical Chemistry Department of Chemistry Department of Chemistry Kemicentrum Safety and security Contact About Education Master/Bachelor-Projects News and events Research People Instruments COMMONS Center Center for Scattering Methods Home  >  People  >  Senior Scientists  >  Emma Sparr Denna sida på sve

https://www.physchem.lu.se/people/seniors/sparr/news/research/people/ - 2025-11-30

Emma Sparr, Professor

Emma Sparr, Professor | Division of Physical Chemistry Faculty of Science Search Division of Physical Chemistry Department of Chemistry Department of Chemistry Kemicentrum Safety and security Contact About Education Master/Bachelor-Projects News and events Research People Instruments COMMONS Center Center for Scattering Methods Home  >  People  >  Senior Scientists  >  Emma Sparr Denna sida på sve

https://www.physchem.lu.se/people/seniors/sparr/news/people/people/seniors/ - 2025-12-05