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Oxidative damage to lipids is rapidly reduced during migratory stopovers

Most migrating birds need to stopover in between flights in order to refuel. Lately, additional purposes of stopover have been suggested, including physiological recovery from metabolically demanding migratory flight. One apparently unavoidable, but harmful physiological effect of migratory flight is increased oxidative damage to lipids and proteins. We here, for the first time, tested whether mig

Super-Earth ingestion can explain the anomalously high metal abundances of M67 Y2235

We investigate the hypothesis that ingestion of a terrestrial or super-Earth planet could cause the anomalously high metal abundances seen in a turn-off star in the open cluster M67, when compared to other turn-off stars in the same cluster. We show that the mass of the convective envelope of the star is likely only 3.45 × 10-3 M⊙, and hence 5.2 M⊙ of rock is required to obtain the observed 0.128

Α 10-gigawatt attosecond source for non-linear XUV optics and XUV-pump-XUV-probe studies

The quantum mechanical motion of electrons and nuclei in systems spatially confined to the molecular dimensions occurs on the sub-femtosecond to the femtosecond timescales respectively. Consequently, the study of ultrafast electronic and, in specific cases, nuclear dynamics requires the availability of light pulses with attosecond (asec) duration and of sufficient intensity to induce two-photon pr

Essays on Expectations : Information, Formation and Outcomes

The first chapter investigates the relationship between economic media sentiment and individuals’ expectations and perceptions about economic conditions. We test if economic media sentiment Granger-causes individuals’ expectations and opinions concerning economic conditions, controlling for macroeconomic variables. We develop a measure of economic media sentiment using a supervised machine learninThe first chapter investigates the relationship between economic media sentiment and individuals’ expectations and perceptions about economic conditions. We test if economic media sentiment Granger-causes individuals’ expectations and opinions concerning economic conditions, controlling for macroeconomic variables. We develop a measure of economic media sentiment using a supervised machine learnin

Kommunala koncerner : En studie av bolagsstrukturer, budgetar och ägardirektiv

Utvecklingen mot mer komplicerade kommunala koncerner förändrar förutsättningarna för och ställer andra krav på kommunal koncernstyrning. Syftet med denna studie är att kartlägga dels hur de kommunala koncernerna i Skånes kommuner är strukturerade, dels hur den formella styrningen av dessa koncerner är utformad. Fokus är på andra organisationsformer i den kommunala koncernen än nämnds- och förvalt

Global catchment modelling usingWorld-Wide HYPE (WWH), open data, and stepwise parameter estimation

Recent advancements in catchment hydrology (such as understanding catchment similarity, accessing new data sources, and refining methods for parameter constraints) make it possible to apply catchment models for ungauged basins over large domains. Here we present a cutting-edge case study applying catchment-modelling techniques with evaluation against river flow at the global scale for the first ti

Label-free acoustophoretic enrichment of mononuclear cells from blood

We are reporting an efficient, label-free and continuous separation of mononuclear cells (MNC), from blood using microchip acoustophoresis. In standard PBS buffer, MNCs and red blood cells (RBC) display overlapping acoustophoretic mobilities which compromise separation of these cell types from each other. In this paper we capitalize on the fact that MNC and RBC display different acoustophysical pr

Antenatal preparation for the early parenthood period. Development and feasibility of an evidence-based programme for antenatal parental preparation

Att bli förälder är en stor livsomställning och föräldrars upplevelse av första tiden efter att barnet fötts påverkas bland annat av den information och förberedelse de får under graviditeten. Depression efter förlossningen drabbar cirka 10 % av alla föräldrar, något som även kan påverka anknytningen till barnet och därigenom barnets hälsa och utveckling. Tidigare forskning har visat att nyblivna Parents often feel inadequately prepared for challenges of early parenthood. This thesis aimed to develop an evidence-based programme for antenatal preparation for early parenthood and to test its feasibility. The Medical Research Council’s framework for development and evaluation of complex interventions was used to design the three studies.Interviews were conducted with first-time parents; 18 mo

Effects from usage of pre‑trip information and passenger scheduling strategies on waiting times in public transport: An empirical survey based on a dedicated smartphone application

Väntetider är viktiga indikatorer för graden av restidsoptimering och andra beteendemässiga aspekter bland kollektivtrafikresenärer. Såsom tidigare studier visar så är användningsgraden av avgångsinformation för avresa är en viktig faktor för att realisera potentialen i restidsminskningar genom att möjliggöra för resenärer att optimera sina väntetider. Huvuddelen av den empiriska forskningen hittiWaiting times are important indicators of the degree of travel time optimisation andother behavioural traits among public transport (PT) passengers. As previous studieshave shown, the level and usage of pre-trip information regarding schedule or realtime departures are important factors that infuence the potential to realise traveltime savings by enabling PT passengers to optimise waiting times. M

Imagination

Imagination is a human capacity that reproduces and transforms experiences and thoughts. The capacity is manifested in children’s pretend play and is an important part of adults’ ability to process the past, and to plan the future. A first step in the development of imagination is the ability to represent objects and events and to change these representations into alternatives to reality. For adap

Modelling human rostro-caudal neural patterning with a microfluidic morphogenic gradient

The study of biological mechanisms involved in human fetal brain development requires suitable models. To date, most findings have been acquired from animal models that fail to account for human-specific developmental traits. To counteract this limitation, a novel in vitro model is proposed where human pluripotent stem cells are differentiated into a coherent fetal brain tissue in a gradient formi

High performance multiplex acoustophoresis for WBC subpopulation isolation

Recently, acoustophoresis has been used to fractionate white blood cells (WBC) into subpopulations, Grenvall et al. [1]. However, at a sample throughput of 8-10 μl/min the separation has limited bioanalytical application. In order to substantially increase throughput, we have redesigned and developed a new separation system that enables unmatched WBC separation performance at a volume throughput o

Targeted alpha therapy in a systemic mouse model of prostate cancer - a feasibility study

225Ac-PSMA-617 targeted-therapy has demonstrated efficacy in 75-85% of patients; however, responses are not durable. We aimed to establish translatable mouse models of disseminated prostate cancer (PCa) to evaluate effectiveness of 225Ac-PSMA-617 at various disease stages. Methods: C4-2, C4-2B, or 22Rv1 cells were injected into the left ventricle of male NSG mice. Disease progression was monitored

Health professionals’ views on key enabling factors and barriers of national multidisciplinary team meetings in cancer care : A qualitative study

Purpose: Multidisciplinary team meetings (MDTMs) are an integral component of cancer care. Increasingly, virtual MDTMs are used to grant high-quality treatment recommendations across health-care regions, which expands and develops the local MDTM team to a regional or national expert network. We investigated health professionals’ experiences from national, virtual MDTMs for rare cancer with a focus

Determining evacuation capability with biomechanical data

Experimental data on single file pedestrian movement has been analysed and implemented in a prototype movement model. The prototype model is developed to predict movement of persons based on a first principle approach using basic population data such as age, height, gender and response time to adapt the walking speed in a crowd. The experimental data provide the biomechanical information needed inExperimental data on single file pedestrian movement has been analysed andimplemented in a prototype movement model. The prototype model is developed topredict movement of persons based on a first principle approach using basic populationdata such as age, height, gender and response time to adapt the walking speed in a crowd.The experimental data provide the biomechanical information needed in the

Physical bounds and radiation modes for MIMO antennas

Modern antenna design for communication systems revolves around two extremes: devices, where only a small region is dedicated to antenna design, and base stations, where design space is not shared with other components. Both imply different restrictions on what performance is realizable. In this paper a computationally efficient method for calculating the fundamental performance bound on spectral