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Molecular structure and interaction of recombinant human type XVI collagen

Collagen XVI is a minor component of at least two different extracellular fibrillar networks of specialized regions of skin and cartilage. In skin, collagen XVI is integrated into particular fibrillin-rich microfibrils lacking an amorphous elastin core. In cartilage, collagen XVI is a component of small heterotypic D-banded fibrils, mainly occurring in the territorial matrix of chondrocytes. Here,

Structure of As-68 studied via the C-12(Ni-58,pn) reaction

Excited states of As-68 nucleus were populated through the C-12(Ni-58,pn) reaction and investigated by in-beam gamma-spectroscopic methods. The NORDBALL detector array equipped with charged particle and neutron detectors was used to detect the evaporated particles and gamma-rays. The level scheme of As-68 was constructed on the basis of gamma gamma-coincidence relations up to 6 MeV excitation ener

Multiparameter analyses of cell cycle regulatory proteins in human breast cancer: a key to definition of separate pathways in tumorigenesis.

Breast cancer is one of the most common cancer forms affecting many women. The disease nevertheless has widely varying behavior and therefore patient outcome, and an important undertaking is to define and understand the molecular mechanisms behind these actions. Defects in the G1/S transition in the cell cycle affect both tumor proliferation and the fidelity of check points responsible for chromos

Demographics, injury characteristics and outcome of traumatic brain injuries in northern Sweden

Objectives - To describe demographics, injury characteristics and outcome of traumatic brain injury (TBI) in northern Sweden over 10 years. Materials and methods - Data were retrospectively collected on those individuals (n = 332) in Norrbotten, northern Sweden, with a TBI who had been transferred for neurosurgical care from 1992 to 2001. Results - A majority were older men with a mild TBI and an

Recruitment from resting stages among bloom-forming cyanobacteria

Popular Abstract in Swedish BLÅGRÖNALGERS VILOSTADIER—EN VIKTIG LÄNK TILL ALGBLOMNINGAR ALGBLOMNINGAR Algblomningar i Östersjön och i många av våra sydsvenska insjöar har blivit ett vanligt inslag sommartid. Vi vet att övergödning av våra vatten orsakar detta genom att överskottsnäring tillför's från olika mänskliga aktiviteter från land. Dock vet vi inte exakt vad det är som styr när och hur desCyanobacteria are known to form heavy blooms in eutrophicated freshwaters and also form resting stages, associated with the sediments, during harsh growth conditions. These resting stages can serve as inoculum for pelagic populations and function as a potential source for bloom formations. However, the factors involved in initiating recruitment from resting stage to the pelagic phase are not fully

Real time imaging of the rotation mechanism producing interview-based language spaces

The article is advancing the bio-kinetic hypothesis of string rotation. Demonstrated is a stepping function. This function shows that the discovered mechanism is working within single "AaO" units. By attaching a dot to the string, states of rotation can be marked and imaged in real time. In keeping track of the orientation of the dot, sliding over the domains (A, O) is demonstrated and the involve

Internationell politik: hemmaplan och bortaplan

International politics has been characterized as an American social science. This article traces the early development of the discipline in Sweden in the shadow of US hegemony. The advantages and disadvantages of the Swedish decision to keep International Relations (IR) within the broader discipline of Political Science are discussed. Recalling the early tensions between International Politics and

Seniority v=5 States in 89Nb

Yrast and yrare states in the nucleus Nb-89 have been studied in the reaction (Ni(Ar,5p)-Ni-58-Ar-36 by measuring gammagamma coincidences and directional correlation orientation ratios with the OSIRIS array. In addition, gamma-ray singles angular distributions have been taken with the reaction (Ni(Cl,4p)-Ni-58-Cl-35. Up to the highest spins observed (37/2+, 33/2-), the states identified line up wi

Signals From the Embryonic Mouse Pancreas Induce Differentiation of Human Embryonic Stem Cells Into Insulin-Producing {beta}-Cell-Like Cells.

The recent success in restoring normoglycemia in type 1 diabetes by islet cell transplantation indicates that cell replacement therapy of this severe disease is achievable. However, the severe lack of donor islets has increased the demand for alternative sources of beta-cells, such as adult and embryonic stem cells. Here, we investigate the potential of human embryonic stem cells (hESCs) to differ