The Goto-Kakizaki (GK) rat represents a model of hereditary non-insulin-dependent diabetes mellitus (NIDDM), characterized by nonobesity, mild hyperglycemia from early life, impaired glucose tolerance test results, and a markedly defective insulin response to glucose. The rats develop signs of both nephropathy and neuropathy, but, to our knowledge, retinal changes have not been reported so far in

Popular Abstract in Swedish Blekinge tillhörde före freden i Roskilde 1658 Danmark. De östdanska provinserna erövrades av svenskarna och integrerades i det svenska riket. Övergångsproblematiken har i äldre forskning ofta diskuterats och analyserats med begrepp hämtade från en senare tids nationella föreställningar. Men var de motsättningar och konflikter som utvecklades i Blekinge efter övergångenThe object of this thesis is to examine the incorporation of the former Danish province of Blekinge into Sweden after the Treaty of Roskilde in 1658. This question has been analysed before but such studies have usually been coloured by the use of national ideas and notions born of a later age than the period under examination. This thesis analyses the so-called Transition Problem using theoretical

A parallel procedure based on a single-program, multiple-data (SPMD) algorithm is presented for parallel computing of turbulent combustion and flame spread in fires. The computation is based on modeling of radiative turbulent reacting flow and pyrolysis of solid fuel. With angular domain decomposition applied to the parallel computing of radiation and spatial domain decomposition to the computatio

Cellobiose dehydrogenase (CDH) is a monomeric protein consisting of two subdomains: a larger flavin-associated domain (DHcdh) and a smaller heme-binding domain (CYTcdh), connected via a protease cleavable linker region. In this study, the inter-domain electron transfer, using the CDH from the ascomycete fungus Myriococcum thermophilum and thiol (SAM) modified gold electrodes, was investigated with

We find that the nature and origin of the proposed "dialogical cognitive representations" in the target article is not sufficiently clear. Our proposal is that (triadic) bodily mimesis and in particular mimetic schemas-prelinguistic representational, intersubjective structures, emerging through imitation but subsequently interiorized-can provide the necessary link between private sensory-motor exp

Background: Current models of group and team development generally favour a linear progressive developmental pattern (Tuckman-Wheelan), taking for granted that all groups move from relative irrationality and inefficency to rationality and efficiency through learning or maturation in sequential stages. Aims: (i) To question the generality of the linear progressive models of group development, (ii)

The dynamics of the excited states of the carotenoid peridinin in polar solvents were studied using femtosecond transient absorption spectroscopy in the spectral range of 500-1900 nm. A broadening of the absorption spectrum in polar solvents is caused by a distribution of conformers having different ground-state properties. In addition, the dependence of the peridinin lifetime on the excitation wa

Kunskapssammanfattning och rekommendationer för ytbehandling av puts och murverk. Skriften syftar till att ge förvaltare, beställare och konsulter förståelse för hur olika faktorer påverkar valet av ytbehandling samt konsekvenser av olika ytbehandlingar.

Ultrafiltration was used during extracorporeal circulation (ECC) with heart-lung machine in 17 critically ill cardiac patients. In ultrafiltration (hemofiltration), water and small molecules (e.g. urea, creatinine and electrolytes), are separated from the blood by hydrostatic pressure generated on the blood side of a semipermeable membrane. The patients had severe water overload for three reasons,

We have identified and characterized a human endogenous retrovirus (HERV) gag transcript in the human pre-B cell leukemia line Reh. The transcript was found to be a splice product of a structurally intact HERV element located on chromosome 6q13. Its primer binding site is complementary to phenylalanine (F) tRNA, common for the HERV-F family, but the overall genome sequence is closely related to th

The influence of subphase characteristics (ionic strength, pH, and the presence of bridging cations) on the conformation and lateral orientation of the hydrophobic polypeptide poly-(L)-leucine (p-leu) has been investigated at the air-water interface with the surface film balance technique as well as with Brewster angle microscopy (BAM). In addition, Langmuir-Blodgett films of p-leu deposited on qu

Two new biological active cyclopentenones VM 4798-1a (1a) and VM 4798-1b (1b) were obtained as a 3 : 1 inseparable mixture from fermentations of Dasyscyphus sp. A47-98. The mixture of the two isomers showed cytotoxic and weak antibacterial and antifungal properties. VM 4898-1 (2-hydroxy-3,4-dimethyl-2-cyclopenten-1-one, 4), produced by another Dasyscyphus sp. showed no significant biological activ

Popular Abstract in Swedish Denna avhandling behandlar en aspekt av religiös beskyddsmetaforik, nämligen den metaforiska användningen av olika ord för det defensiva vapen som vi idag kallar sköld, i den Hebreiska bibeln, den egyptiska och den assyriska litteraturen. Sköldmetaforen kan sägas vara en relationsmetafor ("relational metaphor") vilket avser en typ av metaforer som används för att uttrycThis thesis discusses the religious metaphorical use of different words for "shield" in the Hebrew Bible and Egyptian and Assyrian literature. The literary contexts in the analysis are delimited based on the observation that they share a similar view of divine intervention in war and an analogous view of the enemy. Using the defensive weapon that we today call the "shield" often meant the differen

This paper is a study of the effects of valve timing and how it influences the in-cylinder fluid flow, the combustion, and the efficiency of the engine. An engine load of 4.0 bar imepdndedt was achieved by setting the inlet valve closing time early or late to enable unthrottle operation. Inlet valve deactivation was also used and asymmetrical valve timing, i.e., valve timing with the two inlet val