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Amino acid starvation is sensed by Escherichia coli RelA and Bacillus subtilis Rel through monitoring the aminoacylation status of ribosomal A-site tRNA. These enzymes are positively regulated by their product-the alarmone nucleotide (p)ppGpp-through an unknown mechanism. The (p)ppGpp-synthetic activity of Rel/RelA is controlled via auto-inhibition by the hydrolase/pseudo-hydrolase (HD/pseudo-HD)
This paper introduces the special issue on “Generating Sustainability-Supporting Knowledge on Social Networks in the Governance and Management of Social–Ecological Systems.” Understanding the interactions of actors and institutions is important for successful governance of human–nature relations. Social network analysis is able to capture and analyze these governance and management interactions, a
Stakeholder groups engage in ecosystem services coproduction as both coproducers and beneficiaries. Stakeholder group perceptions of their own and each other’s roles in ecosystem services coproduction therefore influence how ecosystem services are provided in a given landscape. However, only a few studies have investigated self-perceived and attributed stakeholder group roles in this context. The
Background: Frontline nurses have been directly exposed to the SARS-CoV-2 virus and come in close contact with patients during the COVID-19 pandemic. Nurses execute tasks related to disease control and face multiple psychosocial challenges in their frontline work, potentially affecting their mental well-being and ability to satisfyingly perform their tasks.Objectives: To explore the psychosocial e
While much has been written about how startups work to develop their product, this paper focuses instead on how to manage the startup team. Based on a systematic review of current research, I present actionable insights about startup team characteristics; who they are, how they work, and how they stay together. I explain how these characteristics imply both opportunities and threats for the viabil
Background In the early 1980s, a preservative containing a mixture of methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) in a ratio of 3:1 was introduced. This mixture (mix) has been patch tested at 100 ppm (0.01%) worldwide and at 200 ppm (0.02%) in Sweden since 1986 and also in the European baseline series since 2014. Objective A new aqueous mix of MCI 0.015% and MI 0.2% was compar
Summary . Pied Flycatchers Ficedula hypoleuca are known to be victims of nest killings in contexts of competition for nest boxes. However, there is only anecdotal information on their opposite role as perpetrators of nest takeovers and occasional killings of other songbirds. Over 31 years we examined whether competition with Great Tits Parus major over nest box ownership is a significant source of
Relationen mellan socialarbetare och klienter beskrivs som central för socialt arbete men är ett brett och mångtydigt begrepp. Idag stärks och utmanas relationen genom digitalisering. Syftet med denna konfigurativa litteraturöversikt är att förstå hur forskning om socialt arbete mellan 2015 och 2020 beskriver och analyserar digitaliseringens betydelse för relationen mellan socialarbetare och klien
The increase in wildfire occurrence and severity seen over the past decades in the boreal and Arctic biomes is expected to continue in the future in response to rapid climate change in this region. Recent studies documented positive trends in gross primary productivity (GPP) for Arctic boreal biomes driven by warming, but it is unclear how GPP trends are affected by wildfires. Here, we used satell
Aims To investigate liver-related and all-cause mortality among amphetamine users with hepatitis C virus (HCV) infection and compare this with opioid users with HCV infection and the uninfected general population. Methods In this national register study of mortality in persons notified with HCV infection 1990–2015 and a substance-related diagnosis in Sweden, amphetamine users (n = 6,509) were comp
BACKGROUND: Axillary staging via sentinel lymph node biopsy (SLNB) is performed for clinically node-negative (N0) breast cancer patients. The Skåne University Hospital (SUS) nomogram was developed to assess the possibility of omitting SLNB for patients with a low risk of nodal metastasis. Area under the receiver operating characteristic curve (AUC) was 0.74. The aim was to validate the SUS nomogra
In this note, we show that the first-order logic IK! is sound with regard to the models obtained from continuum-valued Łukasiewicz-models for first-order languages by treating the quantifiers as infinitary strong disjunction/conjunction rather than infinitary weak disjunction/conjunction. Moreover, we show that these models cannot be used to provide a new consistency proof for the theory of truth
