Background: The association between lobular breast cancer and family history is not clear. The aim of the study was to possibly identifying new hereditary patterns predisposing for cancer in the different histopathologic subtypes of breast cancer, with focus on patients with lobular breast cancer and cancer in their first degree relatives. Methods: In 1676 consecutive breast cancer patients detail

The Winter Moth (Operophtera brumata L., Lepidoptera: Geometridae) utilizes a single hydrocarbon, 1,Z3,Z6,Z9-nonadecatetraene, as its sex pheromone. We tested the hypothesis that a fatty acid precursor, Z11,Z14,Z17,19-nonadecanoic acid, is biosynthesized from α-linolenic acid, through chain elongation by one 2-carbon unit, and subsequent methyl-terminus desaturation. Our results show that labeled

The resting spores of Plasmodiophora brassicae, causal agent of clubroot disease of crucifers, are tolerant structures with the abitity to survive for at least 15 years in soil waiting for a host. The influence of incorporation of cut grass (Lolium perenne) and presence of the earthworm Aporrectodea caliginosa on R brassicae resting spores was investigated in a microcosm experiment, and measured a

This article explores the development of market integration within the Baltic Sea region and with England, from the 1840s to the late 1880s. It exploits two new datasets on grain prices. The degree of market integration is estimated using a wavelet variant of dynamic factor analysis that takes account of both time and distance. Additionally, we use the London corn market as the benchmark for the d

Vibrational coherences in a photoexcited cyanine dye are preserved for the time-scale of diffusive torsional motion to the bottom of the excited-state potential. The coherently excited modes are virtually unaffected by solvent friction and thus distinct from the bond-twisting motion, which is strongly coupled to the surrounding solvent. We correlate the modes apparent in the resonance Raman and th

Objectives:We hypothesized that common variants in the collagen genes COL4A1/COL4A2 are associated with sporadic forms of cerebral small vessel disease.Methods:We conducted meta-analyses of existing genotype data among individuals of European ancestry to determine associations of 1,070 common single nucleotide polymorphisms (SNPs) in the COL4A1/COL4A2 genomic region with the following: intracerebr

We performed a meta-analysis of 14 genome-wide association studies of coronary artery disease (CAD) comprising 22,233 individuals with CAD (cases) and 64,762 controls of European descent followed by genotyping of top association signals in 56,682 additional individuals. This analysis identified 13 loci newly associated with CAD at P < 5 x 10(-8) and confirmed the association of 10 of 12 previously

Background: Although uncomplicated cystitis is often self-limiting, most such patients will be prescribed antibiotic treatment. We are investigating whether treatment of cystitis with an NSAID is as effective as an antibiotic in achieving symptomatic resolution. Methods/Design: This is a randomized, controlled, double blind trial following the principles of Good Clinical Practice. Women between th

Although Disordered Eating Behaviors (DEB) is an ill-defined concept, multiple studies have examined prevalence of DEB and its relations to other variables in various populations. DEB have been shown to predict more serious eating disorders which in turn can lead to death. Mostly girls seem to suffer from DEB, but the question has been raised whether this, at least, partially is due to the methods

This paper treats the feasibility to use only the sign bit of the in-phase and quadrature components when estimating time and frequency in OFDM systems. Using only the sign bit is shown to result in a frequency dependent bias, which can be easily compensated. The approach is evaluated for LTE and DVB-H, where the estimation is performed using the cyclic prefix, and for WLAN 802.11g, where the estim

Secretory leukocyte protease inhibitor (SLPI) is a protein with anti-protease and antimicrobial properties that is constitutively secreted from the airway epithelium. The importance of maintaining a balance between proteases and anti-proteases, and robust innate defence mechanisms in the airways, is exemplified by inflammatory lung conditions such as chronic obstructive pulmonary disease (COPD) an

A fully three-dimensional anisotropic elastic model for vascular tissue modelling is here presented. The underlying strain energy density function is assumed to additively decouple into volumetric and deviatoric contributions. A straightforward isotropic neo-Hooke-type law is used to model the deviatoric response of the ground substance, whereas a micro-structurally or rather micro-sphere-based ap

Tubular ceramic membranes with many, small-diameter feed flow channels have the advantage of being less costly per unit membrane area. For this reason, membranes with many small channels are often favored over those with fewer larger channels. We have theoretically studied how the diameter of the feed flow channels influences the frictional pressure drop, the membrane performance (flux and retenti

Two conceptual tools in historical analyses of environmental issues and political ecologies have gained much attention in recent years: ecologically unequal exchange and landesque capital. The former narrows in on how societal relations of power allow for the physical transfer of environmental degradation—upon which our daily consumption rests—to places far away from our environmentally clean (and

BACKGROUND: The high prevalence of obesity in children and adolescents emphasizes the necessity to develop evidence-based treatment programs that are useful in a clinical setting. AIMS: The overall aim of the thesis was to develop and evaluate multidisciplinary approaches for management of children and adolescents with obesity. The focus was on generalizability of the treatment in a clinical setti

The intensity-calibrated spectra of W II have been recorded in the spectral interval 23 000-51 300 cm(-1) (1950-4350 angstrom), using the FT500 UV Fourier Transform Spectrometer at Lund Observatory. Combining the intensity data in this work with lifetimes previously measured using the time-resolved laser-induced-fluorescence (TR-LIF) technique resulted in transition probabilities and log gf values