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This paper investigates the relationship between the heterogeneity of the terrestrial carbon cycle and the optimal design of observing networks to constrain it. We combine the methods of quantitative network design and carbon-cycle data assimilation to a hierarchy of increasingly heterogeneous descriptions of the European terrestrial biosphere as indicated by increasing diversity of plant function

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We thank Dr Kurt and colleagues for their comments and interest in our study. High red cell distribution width (RDW) is a new risk factor for cardiovascular disease (CVD), including heart failure, atrial fibrillation and cardiovascular mortality [2-4]. In a recent paper in the Journal of Internal Medicine we reported that low RDW is associated with increased incidence of diabetes [1]. This article

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Ribs are often used in the mid-section of internal turbine blades to augment heat transfer from the blade wall to a coolant, but most research works are concerned only with continuous ribs attached to the side walls. In this paper, a turbulent flow and heat transfer of a rectangular passage with continuous and truncated ribs on opposite walls have been predicted numerically. Two types of ribs are

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Having a child with a chronic disease often increases the burden in the family with more hospital visits, treatment administration, and increased worries for the ill child. A cross-sectional, international, multi-centre study in caregivers of children <18 years with haemophilia and inhibitor was performed at Haemophilia Treatment Centres in Sweden, UK, and Canada to evaluate caregivers' burden and

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Cancer evolves dynamically as clonal expansions supersede one another driven by shifting selective pressures, mutational processes, and disrupted cancer genes. These processes mark the genome, such that a cancer's life history is encrypted in the somatic mutations present. We developed algorithms to decipher this narrative and applied them to 21 breast cancers. Mutational processes evolve across a

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To examine whether there is an association between neighborhood deprivation and childhood autism, after accounting for family- and individual-level sociodemographic characteristics.

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Measurements of the total and differential cross sections of Higgs boson production are performed using 20.3 fb(-1) of pp collisions produced by the Large Hadron Collider at a center-of-mass energy of root s = 8 TeV and recorded by the ATLAS detector. Cross sections are obtained from measured H -> gamma gamma and H -> ZZ*. 4l event yields, which are combined accounting for detector efficiencies, f

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We report on the first experimental results of helical differential phase-contrast computed tomography (helical DPC-CT) with a laboratory X-ray tube source and a Talbot-Lau grating interferometer. The results experimentally verify the feasibility of helical data acquisition and reconstruction in phase-contrast imaging, in analogy to its use in clinical CT systems. This allows fast and continuous v

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Subarachnoid hemorrhage (SAH) is most often followed by a delayed phase of cerebral ischemia which is associated with high morbidity and mortality rates. The causes underlying this delayed phase are still unsettled, but are believed to include cerebral vasospasm, cortical spreading depression, inflammatory reactions, and microthrombosis. Additionally, a large body of evidence indicates that vascul

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As corporations are going global, they are increasingly confronted with human rights challenges. As such, new ways to deal with human rights challenges in corporate operations must be developed as traditional governance mechanisms are not always able to tackle them. This article presents five different views on innovative solutions for the relationships between business and human rights that all b

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A scheme for the numerical solution of singular integral equations on piecewise smooth curves is presented. It relies on several techniques: reduction, Nyström discretization, composite quadrature, recursive compressed inverse preconditioning, and multipole acceleration. The scheme is fast and stable. Its computational cost grows roughly logarithmically with the precision sought and linearly with

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Sexual dimorphism in various bone phenotypes, including bone mineral density (BMD), is widely observed; however, the extent to which genes explain these sex differences is unclear. To identify variants with different effects by sex, we examined gene-by-sex autosomal interactions genome-wide, and performed expression quantitative trait loci (eQTL) analysis and bioinformatics network analysis. We co

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Transaction costs (TCs) must be taken into account when assessing the performance of policy instruments that create markets for the diffusion and commercialization of low-carbon technologies (LCTs). However, there are no comprehensive studies on the development and application of transaction cost analysis to LCTs. In this meta-analysis, a wide-ranging evaluation of TCs associated with energy effic

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Certain types of the early repolarization (ER) phenomenon, previously considered to be benign, have been reported to be associated with ventricular fibrillation (VF), both in population-based studies and in the myocardial infarction (MI) settings.

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We introduce a growing random network on a plane as a model of a growing neuronal network. The properties of the structure of the induced graph are derived. We compare our results with available data. In particular, it is shown that depending on the parameters of the model the system undergoes in time different phases of the structure. We conclude with a possible explanation of some empirical data

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Disentangling the contribution of biotic interactions (density-dependent) and environmental heterogeneity (density-independent) to the formation of spatial patterns between predators and prey is crucial for a better understanding of food-web interactions. Most techniques for the analysis of spatial patterns assume that abiotic processes influence the distribution of individuals with similar intens

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The generation and development of effective adsorption materials for arsenic removal are urgently needed due to acute arsenic contamination of water sources in many regions around the world. In the search for these new adsorbents, the application of nanomaterials or nanocomposites, and especially the use of nanoparticles (NPs), has proven increasingly attractive. While the adsorptive performance o

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OBJECTIVETo investigate associations of maternal gestational weight gain and body composition and their impact on offspring body composition and adipocytokine, glucose, and insulin concentrations at age 4 months.RESEARCH DESIGN AND METHODSThis was a prospective study including 31 mother-infant pairs (N = 62). Maternal body composition was assessed using doubly labeled water. Infant body compositio