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Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the peripheral joints that eventually leads to cartilage destruction and bone erosion. The causes of RA remain largely unknown, but considerable evidence suggests a multifactorial aetiology involving both environmental and genetic factors. Large efforts have been directed towards the understanding of the mo
Despite increasing knowledge of attention deficit hyperactivity disorder (ADHD) across the life span, there is still little research on adults' own experiences of being diagnosed with ADHD. The aim of the present study was to explore and describe patients' experiences and perceptions of being diagnosed with ADHD in adulthood. The study can be seen as an attempt to validate the diagnosis from a pat
Light pipes offer a passive way to bring daylight inside deep buildings, such as agricultural buildings. However, the lack of reliable performance predictability methods for light pipes represents a major obstacle preventing their widespread use. This paper evaluates a simulation approach for performance prediction and identifies key light pipe design parameters affecting their daylight transmissi
The valence states of free neutral potassium clusters produced by a gas aggregation source were probed by synchrotron radiation based photoelectron spectroscopy. The first ionization energy (IE) of the clusters was determined to be 10% larger than the work function of bulk potassium. Using electrostatic concepts and the IE, the mean size of the clusters was estimated to be approximate to 2000 atom
Background Protein 4.1R is an important component of die red cell membrane skeleton. It imparts structural integrity and has transmembrane signaling roles by direct interactions with transmembrane proteins and other membrane skeletal components, notably p55 and calmodulin. Design and Methods Spontaneous and ligation-induced phosphatidylserine exposure on erythrocytes from two patients with 4.1R de
A grid differs from traditional high performance computing systems in the heterogeneity of the computing nodes as well as the communication links that connect the different nodes together. In grids there exist users and service providers. The service providers provide the service for jobs that the users generate. Typically the amount of jobs generated by all the users are more than any single prov
Popular Abstract in Swedish Leukemi är en cancersjukdom i blod och benmärg som karakteriseras av en störd blodbildning. Vid normal blodbildning delar sig ett begränsat antal omogna blodceller så kallade blod stamceller (eller hematopoietiska stamceller) och mognar till funktionella blodceller. Genom att dela sig utan att mogna har stamcellerna även potential till at förnya sig själva. När nya stamAcute myeloid leukemia (AML) is a malignant disorder of the blood system. Hematopoietic stem cells (HSCs) supply and maintain this system by differentiating via intermediates into lineage-restricted progenitors that strongly proliferate to keep up with the high turn-over of mature blood cells. In AML, the mechanisms controlling differentiation and proliferation of myeloid cells are disturbed leadi
The aim of the study was to explore the development of functioning impairments and symptom occurrence during the last months of life of advanced cancer patients. Self-reported data from 116 patients who all completed the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) at 3, 2 and 1 month before death were analysed. All functioning as
Background: Observational studies implicate higher dietary energy density (DED) as a potential risk factor for weight gain and obesity. It has been hypothesized that DED may also be associated with risk of type 2 diabetes (T2D), but limited evidence exists. Therefore, we investigated the association between DED and risk of T2D in a large prospective study with heterogeneity of dietary intake. Meth
Making a detour can be advantageous to a migrating bird if fuel-deposition rates at stopover sites along the detour are considerably higher than at stopover sites along a more direct route. One example of an extensive migratory detour is that of the Sharp-tailed Sandpiper (Calidris acuminata), of which large numbers of juveniles are found during fall migration in western Alaska. These birds take a
Background and purpose The remodeling of morselized bone grafts in revision surgery can be enhanced by an anabolic substance such as a bone morphogenetic protein (BMP). On the other hand, BMPs boost catabolism and might cause a premature resorption, both of the graft and of the new-formed bone. Bisphosphonates inactivate osteoclasts and can be used to control the resorption. We studied a combinati
Popular Abstract in Swedish Denna avhandling har fokus på arbetsrehabilitering för personer som är sjukskrivna eller riskerar att bli det. För dem som blir sjukskrivna kan det bli aktuellt med arbetsrehabilitering. Första steget i en sådan är att utreda individens arbetsförmåga. Utredningen ligger sedan till grund för val av fortsatta åtgärder, för utvärdering av rehabiliteringen samt i vissa falThe overall aim of this thesis was to contribute to the development of new instruments for use in work rehabilitation contexts and to investigate whether clients’ perceptions of their work environment changed while participating in a work rehabilitation programme, as well as how they perceived the programme. The work rehabilitation in focus was the Redesigning Daily Occupations (ReDO) programme. T
Abstract in Undetermined In this anthology, twenty-three scholars from seven academic disciplines analyze film in Sweden never distributed to the cinema. Encompassing more than a centurys, the book gives a broad overview of the role of moving images in relation to the the Swedish model welfare state. The material includes amateur film, education film, industrial film and avant-garde film. The book
Evacuation models generally include the use of distributions or probabilistic variables to simulate the variability of possible human behaviours. A single model setup of the same evacuation scenario may therefore produce a distribution of different occupant-evacuation time curves in the case of the use of a random sampling method. This creates an additional component of uncertainty caused by the i
People have always been inclined not to stick with one god alone, not to trust one single religion. One possible conclusion is that history is full of syncretism. Syncretism seems to be disturbing. It disturbs the exclusive relationship between God and his people, and it disturbs the idea of logical purity if things are mixed up in an uncontrolled manner. Two main attitudes towards syncretism are
