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The polyamines spermidine and spermine retard the platination rate of single-stranded DNA oligomers and plasmid

The presence of polyamines in living cells is crucial for survival. Due to their high net charge at physiological pH, polyamines effectively charge neutralize the phosphodiester backbone of DNA in an interaction that also may protect the DNA from external damage. We here present a study illustrating the influence of spermidine and spermine on the platination reactions of the model oligonucleotides

Synthesis, characterisation and catalytic investigation of a new type of PC(sp(3))P pincer Pd(II) complex

The diphosphine cis-1,3-bis[(di-tert-butylphosphino)methyl]cyclohexane (2) has been synthesised and its complexation in palladium chemistry has been investigated. Ligand 2 is capable of tricoordination, for instance as demonstrated by an X-ray crystal structure determination of the complex [Pd(2)I], and it is a rare example of a PC(sp(3))P pincer ligand. A catalytic study of the Heck reaction reve

A state that failed? On the Union of Kalmar, especially its dissolution

This paper gives an overview of the history and historiography of the union between Denmark, Norway, and Sweden in the late middle ages, the Union of Kalmar, trying to overcome the national bias of previous research. When seen in a state formation perspective, the union must be regarded as a serious candidate for statehood. Focusing on its last decades, it is shown that it was an important mental

Object characterization with refractometric digital Fourier holography

We demonstrate a digital holographic method in which two different substances in a blend are discerned. The method requires only one set of exposures and one reconstruction in the plane of focus. The phase is unwrapped by Flynn's discontinuity algorithm to produce an image of the variation of the optical distance of the illuminating wave. Objects with indices of refraction that are higher and lowe

Use of cellular or cordless telephones and the risk for non-Hodgkin's lymphoma

Objectives: To evaluate the use of cellular and cordless telephones as the risk factor For non-Hodgkin's lymphoma (NHL). Methods: Male and female subjects aged 18-74 years living in Sweden were Included during a period from I December 1999 to 30 April 2002. Controls were selected from the national population registry. Exposure to different agents was assessed by questionnalre. Results: In total, 9

Are gadolinium contrast media really less nephrotoxic than iodine agents in radiographic examinations? A comparison in relation to their ability to attenuate x-rays in a pig model

Purpose: To confront the statement that gadolinium contrast media (Gd-CM) are less nephrotoxic than iodine contrast media (I-CM) when used in x-ray angiographic and computed tomographic (CT) examinations. Methods: I) For CT measurements (mean density in Hounsfield numbers) 20-mL syringes filled with I- and Gd-CM at 0.01, 0.02, 0.05 and 0.1 mmol attenuating atoms/mL were scanned in air and in a 30

Does dorsal pedal pulse palpation predict hand-held Doppler measurement of ankle-brachial index in leg ulcer patients?

Correlation between dorsal pedal pulse palpation and hand-held Doppler measurement of ankle pressure in patients referred to a specialized leg and foot ulcer clinic at a dermatological department was investigated. Complete data regarding palpable dorsal pulse and ankle-brachial index (ABI) was available for 510 patients. Palpable dorsal pedal pulse was present in 337 patients and absent in 173. Me

Photocoagulation of diabetic macular oedema--complications and visual outcome

PURPOSE: To describe complications and visual outcome of photocoagulation for clinically significant macular oedema. SUBJECTS AND METHODS: Evaluation of macular oedema and complications of photocoagulation in 194 eyes, defined as subretinal fibrosis, atrophic creep of the pigment epithelium and subretinal neovascularization was based on stereo fundus photo grading. The study included 25 patients w

Spatial and temporal changes in South African solar ultraviolet-B exposure: Implications for threatened taxa

Spatial and temporal changes in South African solar UV-B (280-315 nm) exposure were modeled and mapped at 2.5 km2 resolution using ozone, relative humidity, cloud amount and elevation data. Computations indicated large natural gradients in UV-B exposure ranging from a 34.2% change over 14o of latitude to a 44.2% change over 16o of longitude. Modelling of future scenarios in annual UV-B exposure in

Absence of genetic variation in populations of the liverwort Plagiochila porelloides from northern Greece and southern Scandinavia

Populations of the leafy liverwort Plagiochila porelloides from lowland southern Scandinavia and mountain peaks on mainland Greece were screened for polymorphisms at 16 putative isozyme loci. The study areas were chosen to represent regions severely and mildly affected by the Pleistocene glaciations, respectively. As in an earlier study from Poland, total absence of variability was recorded. It is

Modeling of spectral changes for depth localization of fluorescent inclusion

We have performed modeling of fluorescence signals from inclusions inside turbid media to investigate the influence of a limited fluorescence contrast and how accurately the depth can be determined by using the spectral information. The depth was determined by forming a ratio of simulated fluorescence intensities at two wavelengths. The results show that it is important to consider the background

Survey of the management of patients with minor head injuries in hospitals in Sweden

OBJECTIVES: Development of guidelines for quality assurance in head injury care has to be based on knowledge about how today's management is organized. To address the need for guidelines in minor head injury (MHI), the authors studied management practice in Sweden. METHODS: We performed a cross-sectional mail survey including all 76 hospitals treating head-injured patients. The questionnaire outli

An Emerging Product Approach in Environmental Law: Incorporating the life cycle perspective

Popular Abstract in Swedish Under senare år har produkternas roll uppmärksammats mer och mer inom miljöpolitiken. Det talas allt oftare om behovet av ett livscykeltänkande där produktens påverkan på miljön under olika faser av livscykeln blir en utgångspunkt för politiska åtgärder. I en värld där leverantörskedjorna ofta är långa och involverar aktörer i ett flertal länder kan ett livscykeltänkandOne of the noticeable trends in recent years is that products have received increasing attention in environmental policy. The focus on products and their life cycle impacts is often referred to as ?life cycle thinking?. This implies a shift away from the traditional focus on production processes and the environmental impacts of point-source pollution, towards a stronger focus on emissions from the