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The aim of this study was to evaluate the contribution of insulin processing to the improved meal-related B-cell function previously shown with the DPP-4 inhibitor vildagliptin. Fifty-five patients with type 2 diabetes (56.5 +/- 1.5 years; BMI=29.6 +/- 0.5kg/m(2); FPG = 9.9 +/- 0.2 mmol/l; HbA1c=7.7 +/- 0.1 %) were studied: 29 pateients were treated with vildagliptin and 26 patients with placebo,

The acromioclavicular joint space in standard antero-posterior images of 151 normal subjects was measured. The joint space was significantly wider in men. There was a highly significant reduction of the joint space with age in both men and women and in persons past 60 a joint space of 0.5 mm or less is not pathological. A joint space wider than 7 mm in men and 6 mm in women is abnormal. The measur

We consider the capacity of multiple-input multiple-output systems with. reduced complexity. One link-end uses all available antennas, while the other chooses the L out of N antennas that maximize capacity. We derive an upper bound on the capacity that can be expressed as the sum of the logarithms of ordered chi-square-distributed variables. This bound is then evaluated analytically and compared t

Major histocompatibility complex (MHC) class I molecules present antigenic peptides to CD8+ T cells, providing the basis for immune recognition of pathogen-infected cells. Peptides generated mainly by proteasomes in the cytosol are transported into the lumen of the endoplasmic reticulum by transporters associated with antigen processing (TAP). The maturation of MHC class I molecules is controlled

Hematopoiesis is a lifelong, dynamic process, originating from a low number of hematopoietic stem cells (HSCs) residing in the adult bone marrow with the ability to self-renew and generate all blood lineages throughout life. Recent findings have demonstrated that the Homeobox (Hox) transcription factors are important regulators of both normal and malignant hematopoiesis, controlling proliferation,

The ribonucleoprotein enzyme telomerase synthesizes telomeric DNA by copying an internal RNA template sequence. The telomerase activities of the yeasts Saccharomyces castellii and Saccharomyces cerevisiae-with regular and irregular telomeric sequences, respectively-have now been identified and characterized. The S. cerevisiae activity required the telomerase RNA gene TLC1 but not the EST1 gene, bo

We study a numerical method of calculating the near field of ensembles of arbitrary spheres by extending Mie theory. A recursive method based on the orders of scattering is presented. This method represents a concise way to calculate the near field of aggregates of any number of arbitrary spheres. Numerical examples are given to show its validity. (C) 2004 Optical Society of America.

Interleukin 6 (IL-6) is a multifunctional cytokine and a potent stimulator of bone resorption and has been implicated in the pathogenesis of osteoporosis in postmenopausal women. The aim of this study was to investigate if a functional JL-6 promoter polymorphism (-174) was related to bone mass and fractures in a cohort consisting of 964 postmenopausal Caucasian women aged 75 years. Bone mineral de

The distribution of necks in slender structures obtained using high rate deformation often differs from the distribution obtained under quasistatic conditions. Initial thickness imperfections are often used to initiate necking at certain locations along a specimen surface. At sufficiently large deformation rates, necks may develop at sites that correlate weakly or not at all with the sites of the

Abstract in Danish Formål: Formålet er at beskrive tuberkulosens (tbc.) epidemiologi i Danmark de sidste 25 år, specielt udviklingen i den danske befolkning. Metode: Et registerstudie af anmeldte tilfælde af tbc. i Danmark 1972-1996: Fra 1970-1989 i DIKE's register, fra 1990-1996 i EPI-registeret, epidemiologisk afd., Statens Serum Institut. Resultater: tbc.-incidensen faldt jævnt fra 1972 indtiThe present study is based on notified cases of tuberculosis (TB) in the National tbc. register 1972-1996. A decline in Tb incidence was seen from 1972 and until the mid-1980's. Subsequently the trend has reversed due to an increasing number of TB cases in foreigners. In 1996, 60% of all cases of TB in Denmark were found in foreigners reflecting the rising number of refugees and their families arr

Ore-mining, metallurgy and other industrial activities represent the source of heavy metal and radionuclide contamination in terrestrial and aquatic environments. Physico-chemical processes are employed for heavy metal removal from industrial wastewater. However, limitations due to the cost-effectiveness and the use of contaminating reagents make these processes not environmentally friendly. Biot

This paper presents a solution to panoramic image stitching of two images with co- inciding optical centers, but unknown focal length and radial distortion. The algorithm operates with a minimal set of corresponding points (three) which means that it is well suited for use in any RANSAC style algorithm for simultaneous estimation of geometry and outlier rejection. Compared to a previous method for

Popular Abstract in Swedish Avhandlingen "Emancipation och religion. Den svenska kvinnorörelsens pionjärer i debatt om kvinnans kallelse ca 1860-1900" exponerar en komplex bild av den samhälleliga kontext som var rådande i emancipationsprocessens initialskede. Undersökningen ger vid handen att det vid denna tid förelåg ett samband mellan emancipation och sedlighet. Konservativa samhällsföreträdareThe purpose of the thesis is to chart the ideology that formed the basis for the initial stages of the emancipation of women in Sweden. The focus of the analysis is the debate over what constituted a woman's calling, and her place in public life. The early feminists possessed a Christian outlook with strong liberal overtones, and it was thus specifically theological arguments that the pioneering g