One-stage method of polysulfone (PSf) membrane modification by the addition of polyacrylic acid (PAA, Mn = 250 kg·mol−1) to the coagulation bath during membrane preparation via non-solvent induced phase separation (NIPS) was proposed. The effect of PAA concentration on the membrane structure, hydrophilicity, zeta potential, separation performance and antifouling stability in ultrafiltration of lys

Aggressive cancers are characterized by hypoxia, which is a key driver of tumor development and treatment resistance. Proteins specifically expressed in the hypoxic tumor microenvironment thus represent interesting candidates for targeted drug delivery strategies. Carbonic anhydrase (CAIX) has been identified as an attractive treatment target as it is highly hypoxia specific and expressed at the c

Drones are increasingly becoming a ubiquitous feature of society. They are being used for a multiplicity of applications for military, leisure, economic, and academic purposes. Their application in academia, especially as social science research tools, has seen a sharp uptake in the last decade. This has been possible due, largely, to significant developments in computerization and miniaturization

Svenska historieböcker är ofta genusomedvetna. Den genushistoria som har skrivits bortser dessutom ofta från andra maktförhållanden som påverkat människors liv och samhället i stort. Den här boken är en genushistoria som handlar om kvinnor och män och om maktrelationerna mellan dem – men också om alla Andra.Det finns etniska Andra, sexuella Andra, kroppsliga Andra och många andra Andra. Gemensamt

En studie av tre rättsfall i Rådhusrätten i Malmö, 1911, 1925 och 1940, där ett stort antal homosexuella män åtalades för "otukt som emot naturen är". Genom en närläsning av rättsfallen går det att återskapa Malmös homosexuella subkultur i stadens geografi och även se förändringar i männens självbild och handlingsmönster.

Serum cystatin C concentration correlates negatively with glomerular filtration rate as well as or better than that of serum creatinine, suggesting a constant formation, and elimination from extracellular fluid mainly by glomerular filtration. It is not known, however, how well the renal plasma clearance of this 13-kDa basic polypeptide matches the glomerular filtration rate. This was investigated

The number of seals in the Baltic Sea has increased dramatically in recent years. While growing seal populations are associated with a thriving marine environment, seals interact with coastal fisheries causing significant damages to catches and gears. One fishery that is severely affected is the coastal cod fishery where the negative impact of seals is believed by many to threaten the existence of

Over 99% of the lead present in blood is usually found in erythrocytes. To investigate the nature of this selective accumulation of lead in erythrocytes, the specific binding of lead to proteins in human erythrocytes was studied using liquid chromatography coupled to inductively coupled plasma mass spectrometry (LC-ICP-MS). The principal lead-binding protein had a mass of approximately 240 kDa, an

Human protein HC is a member of the lipocalin superfamily with unique properties since it carries a covalently bound fluorescent chromophore mediating the linkage of the major part of protein HC to several plasma proteins, with IgA as the dominating complex partner. Native protein HC displays characteristic absorption and fluorescence spectra similar to those of glycated proteins with advanced gly

The effects of human cystatin C on bone resorption, enzyme release, osteoclast generation, bone cell proliferation and bone matrix protein biosynthesis have been examined in different in vitro systems. The effects of cystatin C were compared with those of calcitonin and E 64 (trans-Epoxysuccinyl-L-leucyl-amido-(4-guanidino)butane). Recombinant human cystatin C and E 64 dose dependently inhibited t

We studied the influence of diclofenac on the pharmacokinetics of cloxacillin in healthy volunteers, 60 years or older, as well as the possible effect of cloxacillin and diclofenac on urinary protein excretion. In a randomized, double-blind, cross-over study 15 subjects were given 1 g cloxacillin, and placebo or 75 mg diclofenac, as single intravenous doses. Plasma concentrations of cloxacillin we

We studied renal function during and after surgery in 38 patients undergoing total hip replacement (THR) and 21 patients undergoing total knee replacement (TKR). Serum creatinine and renal excretion of albumin, IgG, protein HC and creatinine were recorded preoperatively and on days 1, 2, 4, and 8, THR patients were randomized to treatment with (n 17) or without (n 21) prophylactic isoxazolyl penic

Recent studies have indicated that serum and plasma cystatin C are better markers for glomerular filtration rate (GFR) than serum creatinine, ubiquitously used for this purpose. To fully exploit the value of serum and plasma cystatin C as GFR markers, reliable age and sex-correlated reference intervals are required. The present study comprised cystatin C determinations in plasma and sera from 259