Modern health-care is a complex socio-technical system, and as such variability is normal and necessary. The ability of a complex system such as health-care to quickly and correctly adapt to varying circumstances is crucial to how well the system works. Both increased compliance to guidelines, and a concurrent ability in individuals to deviate from these guidelines in certain situations, can be ex

To date, the best daylighting assessment technique is provided by climate-based simulation tools, which require remarkable efforts to create and calibrate realistic models. The data-driven approaches represent an interesting opportunity to support the physics-based modelling. This work proposes a novel method aimed at the optimization of energy use and luminous environment for a set of lighting co

Gestational diabetes mellitus (GDM) is today universally diagnosed during late pregnancy. Treating hyperglycaemia during pregnancy reduces the risk of complications, the effect of interventions is however limited due to the late diagnosis. It is thus important to identify biomarkers reaching a high precision for GDM development in early pregnancy. Here we aim to investigate soluble CD163 (sCD163)

The article presents some key aspects of the approach called sociology of philosophy, as represented by Pierre Bourdieu, Randall Colins and others. Comparisons are made with the philosophical research programme, developed by Dieter Henrich, which goes under the name constellation research. One thing that unites the sociology of philosophy and constellation research is an interest in antagonistic c

It has been shown that after production of oxophlorin, the first step of intermediate, both production of biliverdin and production of verdoheme occur simultaneously (Alavi et al. in Dalton Trans 47:8283–8291, 2018). So the mechanism that converts biliverdin into verdoheme is the subject of some controversy. The detailed conversion of verdoheme to biliverdin was demonstrated before by the Jerusal

Objective. In cross-sectional studies, elevated osteopontin (OPN) levels have been proposed to reflect, and/or precede, progressive organ damage and disease severity in systemic lupus erythematosus (SLE). We aimed, in a cohort of patients with recent-onset SLE, to determine whether raised serum OPN levels precede damage and/or are associated with disease activity or certain disease phenotypes. Met

1988 uppmättes den allvarligaste syrebristen någonsin i Kattegatt. Syrehalten i vattnet sjönk till rekordlåga nivåer och många bottenlevande djur dog. Även i Östersjön var läget allvarligt. Även om forskarna vid denna tid hade en viss kunskap om problemets utbredning skulle det dröja ända in på 2000-talet innan man fick en heltäckande bild – en bild som delvis förvånade forskarna

Because of their symbiotic origin, many mitochondrial proteins are well conserved across eukaryotic kingdoms. It is however less obvious how specific lineages have obtained novel nuclear-encoded mitochondrial proteins. Here, we report a case of mitochondrial neofunctionalization in plants. Phylogenetic analysis of genes containing the Domain of Unknown Function 295 (DUF295) revealed that the domai

Sara Bergmark Elfgrens ungdomsskildring Norra Latin möter rösterna som vittnar inom #metoo. Ingrid Bosseldal analyserar.