Aims To compare the British Isles Lupus Assessment Group (BILAG) 2004, the Safety of Estrogens in Lupus Erythematosus National Assessment (SELENA) flare index (SFI) and physician's global assessment (PGA) in assessing flares of disease activity in patients with systemic lupus erythematosus (SLE). Methods Sixteen patients with active SLE were assessed by a panel of 16 rheumatologists. The order in

Popular Abstract in Swedish Psoriasis är en av våra vanligaste folksjukdomar, som drabbar 2-3 % av den vuxna befolkningen. Man vet i dag att många patienter med psoriasis lider av psykisk ohälsa och sänkt livskvalitet. Sjukdomen i sig innebär ofta en stor psykologisk påfrestning för patienten, men stress och psykisk ohälsa också kan vara en viktig orsak till insjuknande och återfall av psoriasis. Psychological distress is well known to be associated with psoriasis, both as a disease consequence, and as a causative factor for onset and exacerbations. Psychoneuroimmunological mechanisms have been suggested to be involved in the pathogenesis of psoriasis and have often been shown to be related to psychological distress and pruritus in psoriasis. The general aim of this thesis was to investig

Forskarutbildningen har ett dubbelt syfte, att utbilda framtidens universitetslärare och forskare samt att utgöra rekryteringsbas för andra delar av offentlig sektor och privat sektor. Resultaten av denna alumnundersökning visar att Lunds universitet väl svarar upp mot detta dubbla rekryteringssyfte. Av doktoranderna i undersökningen, riktad till examinerade år 2004, hade nästan nästan samtliga (9

Expression of the RNA-binding motif protein 3 (RBM3) has been shown to correlate with favourable clinicopathological parameters and prognosis in several cancer diseases. The aim of this study was to examine the expression and prognostic ability of RBM3 in patients with testicular non-seminomatous germ cell tumours (NSGCT).

Purpose – The aim is to understand customers' willingness, or unwillingness, to pay a price premium in the market for consumer packaged food and what kind of images brands can use in order to achieve a price premium. Design/methodology/approach – The study is based on a quantitative survey of brand images found in food and branding literature and their impact on loyalty as well as customers' will

The general research question of the present study was to assess the impact of visually salient online adverts on children's task-oriented internet use. In order to answer this question as reliably as possible, an experimental study was constructed in which 9-year-old and 12-year-old Swedish children were asked to solve a number of tasks while interacting with a mockup website. In each trial, web

Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

Controlled vocabularies (CVs), i.e. a collection of predefined terms describing a modeling domain, used for the semantic annotation of data, and ontologies are used in structured data formats and databases to avoid inconsistencies in annotation, to have a unique (and preferably short) accession number and to give researchers and computer algorithms the possibility for more expressive semantic anno

Popular Abstract in Swedish Hur gör bakterier för att komma undan immunförsvaret? Vi har studerat hur en vanligt förekommande bakterie, grupp A streptokocker, gör för att undvika kroppens immunförsvar vid infektion. Vi har upptäckt enzymer som bidrar till bakteriens förmåga att undvika immunförsvaret genom att avväpna antikroppar. De bakteriella enzymerna kan användas i bioteknisk industri och eveA majority of the proteins of the immune system are glycosylated and the glycans of IgG are essential for its functionality. Bacteria display enzymes that modulate the glycans of the immune system to weaken the host defense and favor bacterial survival. In this thesis we aimed at exploring bacterial modulation of host glycosylation in infection and to evaluate the usefulness of bacterial enzymes i

Purpose – To identify and describe the strategic potential of logistics-driven packaging innovation in retail supply chains, and suggest propositions for further research and development, providing practitioners with a better basis on which to make strategic packaging and logistics decisions. Design/methodology/approach – An in-depth case study was conducted at a large global retailer which had im

A 'cap and dip' method of adsorbing ruthenium di-2,2'-bipyridy1-4,4'-dicarboxylic acid diisocyanate (N3 dye) on a rutile TiO2 (110) surface was investigated using pyrocatechol as a capping molecule. This method involves cleaning the rutile surface in ultra-high vacuum (UHV), depositing pyrocatechol onto the surface to 'cap' the adsorption sites, removing from vacuum, 'dipping' in an N3 dye solutio

The Mo2B2Fe-type intermetallic compounds Gd2Cu2In and Gd2Cu2Mg form a complete set of solid solutions Gd2Cu2In1-xMgx. The a lattice parameter, the Weiss constant and the Curie temperature increase with increasing magnesium content in an almost Vegard-like manner, while the c parameter remains almost constant. All members of the solid solutions show ferromagnetism with T(C)s between 114 and 80 K.