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Endothelial-derived prostacyclin is an important regulator of microvascular function, and its main actions are inhibition of platelet/leukocyte aggregation and adhesion, and vasodilation. Disturbances in endothelial integrity following traumatic brain injury (TBI) may result in insufficient prostacyclin production and participate in the pathophysiological sequelae of brain injury. The objective of

In order to identify biological processes relevant for cell death and survival in the brain following stroke, the postischemic brain transcriptome was studied by a large-scale cDNA array analysis of three peri-infarct brain regions at eight time points during the first 24 h of reperfusion following middle cerebral artery occlusion in the rat. K-means cluster analysis revealed two distinct biphasic

Alkaline sphingomyelinase (Alk-SMase) and neutral ceramidase (N-CDase) in the intestinal microvillar membrane are responsible for dietary sphingomyelin digestion. The activities of the enzymes require the presence of bile salt, and the enzymes can be released into the gut lumen in active forms by bile salts and trypsin. It is unclear to what extent that the intestinal presence of bile salts is cri

Artikeln rör den historiekulturella frågan huruvida folkmordet på judarna skall skrivas Förintelsen eller förintelsen.

Various occupational exposures have been monitored by chromosomal aberrations, sister chromatid exchanges and micronuclei in peripheral blood lymphocytes. During the last decade, epidemiological studies have evaluated whether any of these markers foreshadows cancer risk. Results from Nordic, Italian and Czech cohorts support an approximately twofold cancer risk among subjects with high frequencies

The use of water mist for fire extinguishment has increased rapidly in recent years. The main reason is the abandonment of halon-based extinguishing systems in favour of environmentally friendlier systems. Furthermore the use of water mist systems has spread from mainly marine applications to also include the protection of buildings. The main problem in this regard is to verify the effectiveness o

We have investigated the transport of spin polarization through a classically chaotic semiconductor loop with a strong Rashba spin-orbit interaction. We found that if the escape time of a particle is long enough, the configuration averaged spin conductance oscillates strongly with the geometric spin phase. We predict a sizable rotation of spin polarization along its flowing path across the loop fr

Så kallade neurala nätverk används nu inom många fält. Medicinska applikationer bör- jar komma. Dataprogram som har förmåga att känna igen mönster och genom inlärning kan kategorisera data på ett sätt som liknar den erfarne lä- karens kan bli verklighet. Neu- rala nätverk för att klassificera patienter med leversjukdomar har med framgång provats.

Given a set V of n points in R-d and a real constant t > 1, we present the first O(n log n)-time algorithm to compute a geometric t-spanner on V. A geometric t-spanner on V is a connected graph G = ( V, E) with edge weights equal to the Euclidean distances between the endpoints, and with the property that, for all u, v is an element of V the distance between u and v in G is at most t times the Euc

Research within nursing and medicine is moving at an increasing pace. This makes it difficult for the staff - involved with medical care to find the right path through all the new research and development. Working according to evidencebased procedures within both medicine and nursing means using in one’s work the recommendations which have been based on literature studies that have compiled, revie

Iterative numerical schemes for solving the electrostatic partial differential equation with variable conductivity, using fast and high-order accurate direct methods for preconditioning, are compared. Two integral method schemes of this type, based on previously suggested splittings of the equation, are proposed, analyzed, and implemented. The schemes are tested for large problems on a square. Par

Popular Abstract in Swedish Denna rapport behandlar trafiklaster på broar och de lasteffekter som de ger upphov till. Böjmoment och tvärkraft för olika brotyper beskrivs i form av statistiska fördelningar med tillhörande parametrar. Dessa är baserade på mätningar av verklig trafik gjorda i Sverige under åren 2002-2003 i Vägverkets regi. Resultaten finns redovisade i Vägverket (2004b), och finns laThis thesis treats traffic load effects in road bridges and in particular bending moment and shear force in different types of bridges. All traffic load effects are described in terms of statistical distribution functions for annual extreme values. The statistical distributions are based on measurements of real traffic, made in Sweden during 2002-2003. The measurements are managed by the Swedish R

Lacunar infarcts, small deep infarcts resulting from occlusion of a penetrating artery, account for about a quarter of all ischemic strokes. The view of lacunar infarcts as a benign and rather innocent vascular lesion has been modified during the last years. Although the prognosis is more favourable than other subtypes during the first years, probably due to the small lesion size, in a longer pers