Search results

Filter

Filetype

Your search for "*" yielded 532991 hits

Rapid decarbonisation of cities by addressing behavioural failures? A critical review of policy interventions

While many of the interventions to reduce carbon emissions target market failures, little attention is given to behavioural failures. This study investigates to what degree cities, which have taken a central role in global decarbonisation efforts, already incorporate findings from behavioural economics in their policy interventions. The ‘traditional taxonomy’ for policy intervention, represented a

How to support teenagers who are losing a parent to cancer : Bereaved young adults' advice to healthcare professionals—A nationwide survey

Objective:: The loss of a parent to cancer is considered one of the most traumatic events a teenager can experience. Studies have shown that teenagers, from the time of diagnosis, are already extremely worried about the consequences of a parent's cancer but tend to be left to manage these concerns on their own. The present study aimed to explore young adults' advice to healthcare professionals on

The shrunken pore syndrome is associated with declined right ventricular systolic function in a heart failure population – the HARVEST study

The close relationship between heart and kidney diseases was studied with respect to the ‘Shrunken pore syndrome’ that is characterized by a difference in renal filtration between cystatin C and creatinine. Patients were retrieved from the HeARt and brain failure inVESTigation trail (HARVEST) which is an ongoing study undertaken in individuals hospitalized for the diagnosis of heart failure. Ninet

Strategies to obtain pattern fidelity in nanowire growth from large-area surfaces patterned using nanoimprint lithography

Position controlled nanowire growth is important for nanowire-based optoelectronic components which rely on light emission or light absorption. For solar energy harvesting applications, dense arrays of nanowires are needed; however, a major obstacle to obtaining dense nanowire arrays is seed particle displacement and coalescing during the annealing stage prior to nanowire growth. Here, we explore

High-Performance Lateral Nanowire InGaAs MOSFETs with Improved On-Current

We report on In0.85Ga0.15As MOSFETs utilizing selectively grown lateral nanowires as the channel. These devices exhibit ON-current of ION = 565μ/Aμm at IOFF =100 nA/μm and VD=0.5 V, which is higher than all other reported values for III-V FETs. This is enabled by a transconductance of 2.9 mS/μm and a minimum SSsat of 77 mV/decade. A ballistic top-of-the-barrier model is used to model these devices

Using Alliances to Cut the Learning Curve of ICT

Information and Communication Technology (ICT) is arguably an important, emblematic and ubiquitous technology of contemporary society. For many incumbent firms, the infusion of ICT into their industries poses both threats and opportunities. It might drive significant shifts of financial wealth and make firm performance change drastically. It entails managerial challenges of a kind we might not hav

Integrative Taxonomy Recognizes Evolutionary Units Despite Widespread Mitonuclear Discordance : Evidence from a Rotifer Cryptic Species Complex

Mitonuclear discordance across taxa is increasingly recognized as posing a major challenge to species delimitation based on DNA sequence data. Integrative taxonomy has been proposed as a promising framework to help address this problem. However, we still lack compelling empirical evidence scrutinizing the efficacy of integrative taxonomy in relation to, for instance, complex introgression scenario

Elevated basal insulin secretion in type 2 diabetes caused by reduced plasma membrane cholesterol

Elevated basal insulin secretion under fasting conditions together with insufficient stimulated insulin release is an important hallmark of type 2 diabetes, but the mechanisms controlling basal insulin secretion remain unclear. Membrane rafts exist in pancreatic islet cells and spatially organize membrane ion channels and proteins controlling exocytosis, which may contribute to the regulation of i

Cerebrospinal fluid tau, neurogranin, and neurofilament light in Alzheimer's disease

Cerebrospinal fluid (CSF) tau (total tau, T-tau), neurofilament light (NFL), and neurogranin (Ng) are potential biomarkers for neurodegeneration in Alzheimer's disease (AD). It is unknown whether these biomarkers provide similar or complementary information in AD. We examined 93 patients with AD, 187 patients with mild cognitive impairment, and 109 controls. T-tau, Ng, and NFL were all predictors

The protease inhibitor cystatin C downregulates the release of IL-β and TNF-α in lipopolysaccharide activated monocytes

Human cystatin C, a member of the cysteine proteinaseinhibitory family, is produced by all nucleated cells and has important roles in regulating natural immunity. Nematode homologs to human cystatin C have been shown to have anti-inflammatory effects on monocytes and to reduce colitis in mice. In Crohn’s disease, pathogenic activated monocytes help drive inflammatory processes via the release of p

Experimental and numerical study on heat transfer and pressure drop performance of Cross-Wavy primary surface channel

The Cross-Wavy primary surface heat exchanger is one of the most promising candidates for microturbine recuperators. In this paper, naphthalene sublimation experiments are performed for Cross-Wavy channels in a wind tunnel. The experimental results indicate that the entrance region has a small effect on the unit-averaged heat transfer coefficient of whole Cross-Wavy channels. Correlations of Nusse

Assessing regional progress towards a ‘Green Energy Economy’

This paper provides a regional, empirical analysis of policy portfolios that aim to contribute towards a ‘Green Energy Economy’ (GEE) transformation. Taking green economy policies and related indicators as the analytical framework, the study examines (i) the composition of policy portfolios promoting low-carbon energy technologies, (ii) short-term trends related to the GEE, (iii) long-term empiric

Molecular Dynamics Simulations of Intrinsically Disordered Proteins: On the Accuracy of the TIP4P‐D Water Model and the Representativeness of Protein Disorder Models

Here, we first present a follow-up to a previous work by our group on the problematic of molecular dynamics simulations of intrinsically disordered proteins (IDPs) [Henriques et al. J. Chem. Theory Comput. 2015, 11, 3420−3431], using the recently developed TIP4P-D water model. When used in conjunction with the standard AMBER ff99SB-ILDN force field and applied to the simulation of Histatin 5, our

Complementary strategies to improve positive response and outcome in patients with advanced heart failure undergoing CRT therapy

AbstractCardiac resynchronization therapy (CRT) has improved quality of life and survival in select heart faillure patients, however 30-40% of patients do not show objective benefit from the treatment. At the same time there is little evidence about the long term effect of changes in medical treatment in these patients. Several factors have been examined to improve the response rate in the ”non-re

Positive Response to Cardiac Resynchronization Therapy : The Role of NT-proBNP

Abstract Background: Cardiac resynchronization therapy (CRT) is effective, but only 60-70% of patients benefit from the therapy. Despite numerous implantations, identification of predictive factors for response is still a challenge. We sought to assess the correlation of echocardiographic and clinical response to baseline demographics in relation to change in NT-proBNP levels at 6 months. Methods:

Savoring Life with an Unsympathetic World View : Sabbath as Rest and Contemplation in Gospel of Thomas Logion 27

This article discusses the enigmatic logion 27 in the Gospel of Thomas. It argues that preconceived notions of the text being “Gnostic” have affected previous interpreta- tions of how the Sabbath is portrayed in logion 27. A discussion follows concerning the many different interpretations of the elusive second part of the logion and the phrase σαββατίσητε τὸ σάββατον/ⲉⲓⲣⲉ ⲙ̄ⲡⲥⲁⲙⲃⲁⲧⲟⲛ ⲛ̄ⲥⲁⲃⲃⲁⲧⲟⲛ. T

Gnostiker som antikens feminister? : kvinnans roll och bilden av det feminina i antik gnosticism

In this article the notion that women retained a special position among ”Gnostics”, compared the surrounding context, is questioned. It is pointed out that there are no necessary correlation between myth and social reality. Finally, it is argued that proto-orthodox portrayals of “Gnostics” as favoring women should chiefly be under-stood as a polemical technique meant to discredit ones opponents.

Uncovering symmetries in polynomial systems

In this paper we study symmetries in polynomial equation systems and how they can be integrated into the action matrix method. The main contribution is a generalization of the partial p-fold symmetry and we provide new theoretical insights as to why these methods work. We show several examples of how to use this symmetry to construct more compact polynomial solvers. As a second contribution we pre

Health care utilisation among older persons with intellectual disability and dementia : a registry study

BACKGROUND: Both persons with intellectual disability (ID) and persons with dementia have high disease burdens, and consequently also high health care needs. As life expectancy increases for persons with ID, the group of persons with the dual diagnosis of ID and dementia will become larger.METHOD: Through national registries, we identified 7936 persons who had received support directed to persons