Expression of the epidermal growth factor (EGF) receptors HER1 and HER2 has been implicated in tumour growth and poor survival, whereas expression of HER3 and HER4 has been associated with improved survival of bladder cancer patients. The balance between the expression of the EGF family members may therefore have a role to play in determining the final outcome in cancer cells. To check this, we ex

The production cross section of inclusive isolated photons has been measured by the ALICE experiment at the CERN LHC in pp collisions at a centre-of-momentum energy of s= 7 TeV. The measurement is performed with the electromagnetic calorimeter EMCal and the central tracking detectors, covering a range of | η| < 0.27 in pseudorapidity and a transverse momentum range of 10

Återkommande utbrott av mässling i Europa och Nordamerika har väckt frågan omobligatoriska vaccinationsprogram till liv både i Sverige och i andra delar av världen. I detta kapitel redovisas unika resultat från 2018 års nationella SOM-undersökning, som visar hur stödet för obligatorisk barnvaccination skiljer sig åt mellan olika samhällsgrupper i Sverige. Analysen visar att det finns ett stort stö

What makes a business model successful? In this book the roots of business models are traced to the concept of the “business idea” which was popularized by researchers in the 1960s and 1970s. The business idea stresses the importance of conformance between the market and the product system, as well as between the product system and the internal features of the firm.A distinguishing feature of the

This article poses the question of how storytelling takes place in free guided tours. It aims to explore guides’ contributions to the glocalization of urban places. Theoretically, the study departs from the concepts of glocalization, place, and storytelling. Empirically, it builds on data from Copenhagen, Berlin, Warsaw and Tallinn, collected by means of participant observations and document studi

Purpose: From the background of the dramatic increase of urban tourism, framed by the concept of overtourism, the purpose of this paper is to analyze and discuss current dynamic processes of urban tourism growth, as presented in the scientific literature. With the help of a literature review, this paper aims to discuss current definitions and conceptualizations of overtourism and discuss the drivi

A measurement of W± boson production in Pb+Pb collisions at sNN=5.02Te is reported using data recorded by the ATLAS experiment at the LHC in 2015, corresponding to a total integrated luminosity of 0.49nb-1. The W± bosons are reconstructed in the electron or muon leptonic decay channels. Production yields of leptonically decaying W± bosons, normalised by the total number of minimum-bias events and

The production cross-sections for W± and Z bosons are measured using ATLAS data corresponding to an integrated luminosity of 4.0 pb- 1 collected at a centre-of-mass energy s=2.76 TeV. The decay channels W→ ℓν and Z→ ℓℓ are used, where ℓ can be an electron or a muon. The cross-sections are presented for a fiducial region defined by the detector acceptance and are also extrapolated to the full phase

We present calculations for attosecond atomic delays in the photoionization of noble-gas atoms based on the full two-color two-photon random-phase approximation with exchange in both the length and velocity gauge. Gauge-invariant atomic delays are demonstrated for the complete set of diagrams. The results are used to investigate the validity of the common assumption that the measured atomic delays

Interaction of Streptococcus pneumoniae with the surface of endothelial cells is mediated in blood flow via mechanosensitive proteins such as the Von Willebrand Factor (VWF). This glycoprotein changes its molecular conformation in response to shear stress, thereby exposing binding sites for a broad spectrum of host-ligand interactions. In general, culturing of primary endothelial cells under a def

Standards on product information can facilitate the diffusion of innovations. This paper explores the standards related to the ventilation products with improved acoustic performance and the stakeholders involved. We introduce a new approach to classification and identification of the functions of standards in supporting such innovations. Moreover, our analysis of stakeholders indicates that the c

Mesenchymal stromal (stem) cells (MSCs) are increasingly demonstrated to ameliorate experimentally-induced lung injuries through disease-specific anti-inflammatory actions, thus suggesting that different in vivo inflammatory environments can influence MSC actions. To determine the effects of different representative inflammatory lung conditions, human bone marrow-derived MSCs (hMSCs) were exposed

The momentum measurement capability of the ATLAS muon spectrometer relies fundamentally on the intrinsic single-hit spatial resolution of the monitored drift tube precision tracking chambers. Optimal resolution is achieved with a dedicated calibration program that addresses the specific operating conditions of the 354 000 high-pressure drift tubes in the spectrometer. The calibrations consist of a

This study aims to investigate the cooling performance of various film cooling holes, including combined hole, cylinder hole, conical hole, and fan-shaped hole. For film cooling technology, a novel combined hole configuration is first proposed to improve the cooling protection for gas turbine engines. This combined hole consists of a central cylinder hole (an inclination angle of 35°) and two addi

Positioning is an essential feature in Narrow-Band Internet-of-Things (NB-IoT) systems. Observed Time Difference of Arrival is one of the supported positioning techniques for NB-IoT. It utilizes the downlink NB positioning reference signal (NPRS) generated based on a length-31 Gold sequence. Although a Gold sequence has good auto-correlation and cross-correlation properties, the correlation proper

We consider time-of-arrival (ToA) estimation for a device working in narrowband Internet-of-Things (NB-IoT) systems. Due to a limited 180 kHz bandwidth, the time-domain auto-correlation function (ACF) of transmitted NB positioning reference signal (NPRS) has a wide main-lobe. Without considering that, the performance of ToA estimation can be degraded for two reasons. Firstly, the NPRS correspondin

We propose an improvement over a modulus zero-forcing (MZF) detector proposed earlier in [1] for multi-input multi-output (MIMO) detection, namely, the joint MZF (JMZF) detector. The MZF detector provides better detection-performance than a traditional ZF detector through preserving controllable interferences, which are mitigated later by nonlinear modulus arithmetic operation. However, the MZF de