Popular Abstract in Swedish Parkinsons sjukdom är en av de vanligaste neurodegenerativa sjukdomarna och orsakas av en selektiv förlust av dopaminerga neuron i mellanhjärnans substantia nigra (SN). Detta leder till en minskad mängd dopamin (DA) i hjärnans motoriska centrum, striatum, vilket orsakar de karakteristiska symptomen bradykinesi, muskelrigiditet och tremor. Förlusten av DA neuron i SN skeParkinson's disease is characterized by a progressive degeneration of dopaminergic neurons in the substantia nigra, leading to a loss of dopamine in the target structure striatum and development of motor symptoms, such as bradykinesia, rigidity and tremor. New experimental treatment strategies for Parkinson's disease are aimed at either preventing the degeneration of the dopaminergic neurons, or a

This work presents a fully-functional, microfabricated electrochemical-cantilever hybrid platform with flow control. A new cantilever chip format is designed, fabricated, and mounted in a custom polymer flow cell. Issues such as leakage and optical/electrical access are addressed, and combined mechanical and electrochemical performance is investigated. Lastly, a cantilever is “defunctionalized” in

Abstract is not available

A simulation model for embedding the bias of a transistor is presented. The model exploits the simulator equilibrium point calculation to set the bias point of the transistor. The model uses negative feedback to set the bias point according to what the designer desires. When the simulator goes into its main analyses, the negative feedback is broken and embedded bias sources are added. This way it

A family of 340-bp tandem telomere-associated DNA repeats is present in 50- to 200-kb blocks in seven of the eight paired chromosome ends in Chironomus pallidivittatus. It consists of four main subfamilies, differing from each other by small clusters of mutations. This differentiation may reflect different functional roles for the repeats. Here we find that one subfamily, D3, is consistently local

Composting was performed in an 800-L box and a 500-L, reactor system. The material used was shredded straw of Miscanthus with pig slurry added as a nitrogen source. Chemical and microbial parameters were measured at five degree temperature intervals until the end of the heating phase and then with increasing intervals during the remaining experiment. In both systems, major losses of carbon occurre

Artikeln diskuterar den ökande kommersialiseringen och marknadsföringen av mindfulness i det svenska samhället. I fokus står inte den religiösa eller skolmedicinska kontexten utan marknadens ”må-bra-kontext”. Som ett svar på nyliberalistiska samhällsförändringar profilerade sig under 1990-talet nya privata entreprenörer som coacher eller terapeuter och ett managementtänkande fördes även in i offe