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X-linked agammaglobulinemia (XLA) is an immunodeficiency caused by mutations in the gene coding for Bruton's agammaglobulinemia tyrosine kinase (Btk). A new edition of the database (BTKbase) of Btk mutations has been compiled containing 282 patient entries representing 175 unique molecular events.
Nutrient resorption prior to leaf senescence is an important mechanism of nutrient conservation in forest tree species. However, despite the abundance of literature on the subject, inter-specific comparison of common temperate tree species is complicated by both the variability of resorption efficiency, which is affected by many environmental factors, and methodological differences between the stu
BACKGROUND: Non-progressive labour is the most common complication in nulliparas and is primarily treated by augmentation. Augmented labour is often terminated by instrumental delivery. Little qualitative research has addressed experiences of non-progressive and augmented deliveries. The aim of this study was to gain a deeper understanding of the experience of non-progressive and augmented labour
Pressurized Liquid Extraction was utilized for the extraction of seven selected polychlorinated biphenyls (28, 52, 101, 118, 153, and 180) from a naturally contaminated fishmeal and two feed samples fortified with a naturally contaminated fish oil sample. In order to assure sufficient extraction efficiencies, the extraction solvent, the extraction temperature, and the flush volume were optimised b
Advances in technology, such as laser capture microdissection (LCM), have allowed for the specific sampling of cells within their natural functional micro-environment. In model systems using LCM, we have studied the global protein expression profiles of airway epithelial cells during a response to allergen provocation. Bronchial epithelial cells were first identified and phenotyped histologically
Several experiments and theoretical models of intermediate energy heavy ion collision physics are presented in this thesis. Statistical and dynamical aspects of nuclear collisions are widely discussed these days, particularly in connection with the multifragmentation phenomenon and the possible link to a liquid-gas phase transition in the spinodal region of nuclear matter phase diagram. Experiment
Popular Abstract in Swedish Denna avhandling är resultatet av ett doktorandprojekt vid Kvartärgeologiska avdelningen, Lunds Universitet. Syftet med undersökningen var att rekonstruera vegetations-, klimat- och havsnivåförändringar på Skagi-halvön, norra Island, under sen-Weichsel och tidig-Holocen. Nordatlantområdet genomgick en serie dramatiska klimatväxlingar i samband med övergången från den sSediment sequences from five lakes on the Skagi peninsula, northern Iceland, were subjected to mineral magnetic analysis, carbon analysis, pollen analysis, plant macrofossil analysis, diatom analysis, radiocarbon dating and tephra analysis in order to make detailed reconstructions of vegetation, climate and sea level during the Late Weichselian and Early Holocene. The main purpose was to investiga
Sargeant et al. conclude from model calculations,in their paper [Phys. Rev. C 65 024302 (2002)] that the degree of chaos in normal deformed states does not enhance the decay out from the superdeformed band. We show that this conclusion is based on a rather unlikely assumption.
5-Aminolevulinic acid (ALA) is a common biosynthetic intermediate of both chlorophyll and heme. Glutamyl-tRNAGlu reductase, encoded by the hemA gene, is the initial enzyme of ALA biosynthesis. The presence of several hemA genes provides a possible explanation to the ability of plants to meet the different requirement of chlorophyll and heme using a common biosynthetic pathway. In this work, two ba
This book deals with ’have’ in ancient Greek. Two different types of ’have’-constructions were used, viz., on the one hand, the active transitive verb ἔχω and, on the other hand, the verb εἶναι, ’be’, with a complement in the dative case (here called the ἔστι μοι construction). A transitive ’have’ does not seem to be of Proto-Indo-European origin but rather an innovation in separate Indo-European
Monoclonal antibodies for targeting cytotoxic conjugates to tumor cells are currently being evaluated together with extracorporeal affinity adsorption. The aim of the adsorption was to reduce undesired side effects in normal organs and to increase the tumor-to-normal tissue ratios. This technique is also applicable to several other therapeutic areas such as immune-mediated disorders, that is, auto
Popular Abstract in Swedish Populärvetenskaplig sammanfattning på svenska (Comprehensive summary in Swedish) Uppföljning av blodtryck (BT), medicinering och njurfunktion efter endovaskulär behandling av njurartärsteno's Bakgrund Förträngning av njuren's tillförande blodkärl, njurartärsteno's (RAS), är den vanligaste sekundära formen av högt BT (hypertension) och svarar för ca 1-5% av hypertensiRenal artery stenosis (RAS) causes hypertension, decreased glomerular filteration rate (GFR), and renal ischemia. RAS is progressive and causes 5-16% of all cases of renal failure. Prevalence of RAS in patients with hypertension is 1-5%. Today percutaneous transluminal renal angioplasty (PTRA) with or without stenting is a widely accepted treatment of RAS. Treatment of renal artery occlusion (RAO)
BACKGROUND AND PURPOSE: It is unclear whether stroke in patients with spontaneous dissection of the cervical internal carotid artery (ICAD) is due to thromboembolism or impaired hemodynamics. This study investigated the mechanism of stroke in ICAD by examining brain imaging and cerebrovascular findings of such patients. METHODS: We retrospectively evaluated the prospectively collected brain CT, MR
This paper describes a radio-tracking study of Osmoderma eremita, a large Scarabaeid beetle, living in hollow trees. The study seems to be the first in which radio telemetry has been used with a flying insect in the field. Some 74 adult beetles were tagged with radio transmitters weighing 0.48-0.52 1, and having a nominal battery life of 12-20 days. Transmissions were detected at ranges of up to 3
