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High-resolution core-level spectroscopy study of the ultrathin aluminum oxide film on NiAl(110)

We have studied the ultrathin aluminum oxide film on NiAl(110) by a combination of high-resolution core-level spectroscopy and density functional theory calculations. Energy-dependent core-level data from the O 1s and Al 2p levels allows for a distinction between oxygen and aluminum atoms residing at the surface or inside the aluminum oxide film. A comparison to calculated core-level binding energ

Hälsoval skåne : Fler besöker allmänläkare, färre går till specialist

Efter införande av Hälsoval Skåne har andelen av befolkningen som besökt allmänläkare ökat, liksom antalet besök per invånare. Ökningarna är överlag måttliga, med undantag för äldre män med lägre inkomst, där ökningen är större.Det finns också en minskning av besöken till övriga specialistläkare så att det totala antalet läkarbesök per invånare minskat i vissa grupper. Färre besök hos övriga speci

Comparing retinal function and structure in diabetic maculopathy and retinal detachment with ff-ERG and a combination of mfERG and OCT

Diabetic maculopathy and retinal detachment, especially involving macula, are potentially sight-threatening conditions. Previous evaluations of retinal function, and treatment of these conditions have been subjective methods depending on the examiner or the collaboration with the examined patient. Retinal structure has been based on the subjective evaluation of the ophthalmologist. Development of

Expression of the global regulator SATB1 is an independent factor of poor prognosis in high grade epithelial ovarian cancer

Background: The global gene regulator Special AT-rich sequence-binding protein1 (SATB1) has been reported to reprogramme tumour cells into a more malignant phenotype and associate with poor clinical outcome in several cancer forms. In this study, we investigated the molecular correlates and prognostic impact of SATB1 expression in human epithelial ovarian cancer (EOC). Findings: Immunohistochemica

Striatal adaptations in experimental parkinsonism and L-DOPA-induced dyskinesia

Abstract in German Die Parkinson-Krankheit („Parkinson”) ist eine neurodegenerative Erkrankung die durch den Verlust von Dopamin-produzierenden Nervenzellen in der Substantia Nigra und daraus resultierenden, typischen motorischen Symptomen gekennzeichnet ist. Die Standardbehandlung für Parkinson ist die Gabe von L-DOPA, zum Zweck der Ersetzung des verlorengegangen Dopamins. Eine Langzeittherapie mParkinson’s disease (PD) is a neurodegenerative disorder, characterized by the loss of dopamine (DA) producing neurons in the substantia nigra pars compacta (SNc), resulting in typical motor symptoms. DA replacement with L-DOPA is the standard therapy for PD. However, with treatment duration many patients face the severe treatment complication of L-DOPA-induced dyskinesia (LID), constituting in ab

Truth and Lie Detection in Bluffing

Beliefs in signals that reveal lies and truths are widespread. It is shown that such beliefs may be exploited strategically in signaling games of pure conflict of interest. Truth and lie detection is modeled by signals perceived by the receiver that are emitted with a probability contingent on the truth value of the sender's message. Truth or lie detection of this kind always shrinks the equilibri

Sensory Perception of Rye Bran Particles of Varying Size and Concentration in a Viscous Phase

Sensory evaluation was performed to investigate how size and concentration of small rye bran particles in a continuous phase with varying viscosity influence the sensory perception of grittiness. The threshold for the sensation of grittiness of rye bran particles in a starch gel, evaluated by triangular sensory tests, was very low. The particles were discerned at a concentration of 0.1-0.3%, despi

Modeling Morphological Evolution in the vicinity of coastal structures

A numerical model of beach topography evolution was developed. The model includes five sub-models: random wave transformation model, surface roller model, wave-induced current model, sediment transport model, and morphological change model. The model was validated by two unique high-quality data sets obtained from experiments on the morphological impact of a detached breakwater and a T-head groin

Live Longer, Work Longer? Evidence from Sweden’s Ageing Population

Popular Abstract in English Sweden’s elderly population is growing, propelled by a continuous decline in old-age mortality, while coupled with a persistent replacement level fertility. This changing age structure increases the per worker cost of providing a given age-vector of per capita benefits, encompassing costs for pensions, health care, and all other type of old-age welfare services, which pSweden’s elderly population is growing, propelled by a continuous decline in old-age mortality, while coupled with a persistent replacement level fertility. This changing age structure increases the per worker cost of providing a given age-vector of per capita benefits, encompassing costs for pensions, health care, and all other type of old-age welfare services, which presents a looming challenge

Durable Polysulfones with Densely Sulfonated Segments for Highly Proton Conducting Membranes

Popular Abstract in English Fuel cells have been considered as alternative power source to petroleum oil. Especially, fuel cells have potentials to provide no pollutant emission (e.g., CO2, NOx, SOx) out of the power generation. For instance, once the fuel cells are installed instead of combustion engine in the cars used for commuting, transportation and leisure, the amount of pollutant emission cFuel cells are considered as a promising alternative environmentally benign power source to the existing ones depending on petroleum oil. Especially, proton-exchange membrane fuel cells (PEMFCs) have been intensively developed during the last decade because of their wide application windows including various portable, stationary and transportation applications. The market has been and will be main

Distinctive character of electronic and vibrational coherences in disordered molecular aggregates

Coherent dynamics of coupled molecules are effectively characterized by the two-dimensional electronic spectroscopy. Depending on the coupling between electronic and vibrational states, oscillating signals of purely electronic, purely vibrational or mixed character are observed with the help of oscillation maps, constructed from time-resolved spectra. Amplitude of beatings caused by electronic coh

Pharmacokinetics of budesonide and formoterol administered via 1 pressurized metered-dose inhaler in patients with asthma and COPD.

In 3 open-label studies, the systemic bioavailability of budesonide and formoterol administered via pressurized metered-dose inhaler (pMDI) or dry powder inhaler (DPI) formulations was evaluated in asthma (24 children, 55 adults) or chronic obstructive pulmonary disease (COPD; n = 26) patients. Treatments were administered at doses high enough to estimate pharmacokinetic parameters reliably. Two o

Determination of the Structures of Symmetric Protein Oligomers from NMR Chemical Shifts and Residual Dipolar Couplings

Symmetric protein dimers, trimers, and higher-order cyclic oligomers play key roles in many biological processes. However, structural studies of oligomeric systems by solution NMR can be difficult due to slow tumbling of the system and the difficulty in identifying NOE interactions across protein interfaces. Here, we present an automated method (RosettaOligomers) for determining the solution struc