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Chronic Obstructive Pulmonary Disease: Role of Alpha-1-antitrypsin

The only proven genetic risk factor for Chronic Obstructive Pulmonary Disease (COPD) is an inherited Z (Glu342¡úLys) deficiency of alpha-1-antitrypsin (AAT), a major inhibitor of neutrophil elastase. In vivo, AAT is found in both native (inhibitory) and modified (non-inhibitory) forms. There is now increasing evidence that the different forms of AAT may exhibit biological activities independent of

Java bytecode to hardware made easy with Bluespec System Verilog

This paper presents a method for translation of Java bytecode sequences into synthesizable hardware, using the Bluespec System Verilog (BSV) environment. At the core of our approach lies a BSV description of a subset of Java bytecodes, that can be used to directly translate bytecode sequences into a BSV specification. The result is intended as an accelerator for existing Java processors (JOP, Blue

Lärresurser - hur kan studenternas lärande förstärkas genom användande av öppna digitala lärresurser.

Öppna digitala lärresurser (Open Educational Resources - OER) är resurser som finns tillgängliga på Internet och som kan användas fritt och i många fall också bearbetas fritt. Universitet världen över lägger ut sitt kursmaterial fritt på nätet, t ex MIT, Stanford och Open University. Lunds universitet har nyligen skapat en egen YouTube kanal och kommer snart att finnas på iTunesU och blir alltmer

Att laga revor i samhällsväven - om social utsatthet och sociala risker i den postindustriella staden

Håller Sverige på att glida isär, fragmenteras eller är sprickorna i välfärden få och begränsade? Det är svårt att bortse från att de senaste 30 årens utveckling har inneburit stora förändringar i den välfärdsstat som utvecklades främst efter andra världskriget. I vissa avseenden har skyddsnäten blivit glesare. Utvecklingen har varit särskilt markant efter den ekonomiska krisen i början av 1990-ta

Studies on surface proteins of Gram-positive bacteria

Popular Abstract in Swedish Grupp A streptokocker är bakterier som orsakar halsfluss, svinkoppor och rosfeber. Även allvarligare sjukdomstillstånd kan följa, t ex toxiskt schocksyndrom och nekrotiserande fasciit, som ibland har dödlig utgång. En annan vanlig bakterie är pneumokocken, som ger upphov till lunginflammation, mellanöreinflammation och hjärnhinneinflammation. Dessa vanliga bakterier utgDespite the availability of antibiotics and modern health care, infectious diseases continue to cause great suffering and costs. Bacterial surface proteins are important for the interaction between host and pathogen. This thesis gives an overview of the importance of bacterial surface proteins in Gram-positive bacteria, particularly Streptococcus pneumoniae and Streptococcus pyogenes. A novel cont

Beyond Innovation : Technology, Institution and Change as Categories for Social Analysis

Today's western society is obsessed with change, and more specifically technological change. Innovation is a buzzword in a number of policy areas including research policy, economic policy, and environmental policy. Beyond Innovation counter weighs this present innovation monomania by broadening our thinking about technological and institutional change. It is done by a multidisciplinary review of

Life Stories and Christian Zionist Ideology : A Theoretical Outline of How to Capture the Interplay between Individual and Ideology

Christian Zionism is usually characterized as a theological and political movement grounded in literalist bible hermeneutics and End-time speculations that dedicate unwavering support to the State of Israel and the Jewish people. The prophetic element in Christian Zionism has in later years been downplayed for a more down-to-earth focus on social and political commitment to the well-being of the s

Modelling of Climatic Thermal Actions in Hollow Concrete Box Cross-Sections

The temperature distribution in concrete structures varies as a result of fluctuations in solar radiation, air temperature, wind speed and long-wave radiation. Variations in temperature may cause longitudinal and transverse movements. If these movements are restrained, stresses and strains can be induced, which may contribute to cracking in the structure. To predict such thermal actions in a hollo

Compensation of Head Movements in Mobile Eye-Tracking Data Using an Inertial Measurement Unit

Analysis of eye movements recorded with a mobile eye-tracker is difficult since the eye-tracking data are severely affected by simultaneous head and body movements. Automatic analysis methods developed for remote-, and tower-mounted eye-trackers do not take this into account and are therefore not suitable to use for data where also head- and body movements are present. As a result, data recorded w

Towards computing the parameters of the simple genetic algorithm

The problem of finding appropriate probabilities for crossover and mutation with respect to resampling may be addressed using the Markov chain model. Our efforts in this direction lead through a simplification of the mixing matrix incorporating both probabilities. We present the simplification and discuss some of its ramifications. We expect that it may lead to some improvement of the computationa