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Evidence for structural transition in hairy-rod poly[9,9-bis(2-ethylhexyl)fluorene] under high pressure conditions

We report on an x-ray scattering experiment of bulk poly[9,9-bis(2-ethylhexyl)fluorene] under quasihydrostatic pressure from 1 to 11 GPa at room temperature. The scattering pattern of high molecular weight (HMW) polyfluorene (>10 kg/mol) undergoes significant changes between 2 and 4 GPa in the bulk phase. The 110 reflection of the hexagonal unit cell disappears, indicating a change in equatorial i

Living an Everyday Life Through a Child's Cancer Trajectory: Families' Lived Experiences 7 Years After Diagnosis

The aim of this study was to illuminate the lived experiences of families where a child had survived 7 years from a diagnosis of childhood cancer. This article describes one part of an inductive and longitudinal research project that included 17 families. Four families whose child was diagnosed with cancer 7 years previously were interviewed using a hermeneutical phenomenological approach. The fam

Improved transferase/hydrolase ratio through rational design of a family 1 β-glucosidase from Thermotoga neapolitana.

Alkyl glycosides are attractive surfactants because of their high surface activity and good biodegradability and can be produced from renewable resources. Through enzymatic catalysis one can obtain well-defined alkyl glycosides, something that is very difficult using conventional chemistry. However, there is a need for better enzymes to get a commercially feasible process. A thermostable β-glucosi

Predator body sizes and habitat preferences predict predation rates in an agroecosystem

Top-down control of pest populations by their natural enemies is a crucial ecosystem service supporting agricultural production. The relationship between predator community composition and predation rates of pests remains poorly investigated. A deeper understanding of the processes shaping interaction strength in agroecosystems is needed if we are to accurately predict natural pest control service

Microscopic four-point-probe resistivity measurements of shallow, high density doping layers in silicon

We present room temperature resistivity measurements of shallow, monolayer doped phosphorus in silicon, a material system of interest for both conventional microelectronic manufacturing, and future quantum electronic devices. Using an in-situ variable spacing microscopic four-probe system, we demonstrate the ability to separate the conductivity of the substrate and the doping layer. We show that t

Resonant Soft-X-Ray Emission as a Bulk Probe of Correlated Electron Behavior in Metallic SrxCa1-xVO3

The evolution of electron correlation in SrxCa1-xVO3 has been studied using a combination of bulk-sensitive resonant soft x-ray emission spectroscopy, surface-sensitive photoemission spectroscopy, and ab initio band structure calculations. We show that the effect of electron correlation is enhanced at the surface. Strong incoherent Hubbard subbands are found to lie similar to 20% closer in energy

A new module for constrained multi-fragment geometry optimization in internal coordinates implemented in the MOLCAS package.

A parallel procedure for an effective optimization of relative position and orientation between two or more fragments has been implemented in the MOLCAS program package. By design, the procedure does not perturb the electronic structure of a system under the study. The original composite system is divided into frozen fragments and internal coordinates linking those fragments are the only optimized

Multipolar Plasmon Resonances in Individual Ag Nanorice

We study the optical excitation of high-order surface plasmon resonance modes in individual Ag nanorice particles using dark-field scattering spectroscopy. We analyze the results by model calculations using the boundary element method. Symmetry breaking caused by oblique illumination makes the even order resonance modes observable in the optical spectrum. All the resonance peaks are found to redsh

Study of the Early Flame Development in a Spark-Ignited Lean Burn Four-Stroke Large Bore Gas Engine by Fuel Tracer PLIF

In this work the pre- to main chamber ignition process is studied in a Wärtsilä 34SG spark-ignited lean burn four-stroke large bore optical engine (bore 340 mm) operating on natural gas. Unburnt and burnt gas regions in planar cross-sections of the combustion chamber are identified by means of planar laser induced fluorescence (PLIF) from acetone seeded to the fuel. The emerging jets from the pre-

Characterization of ammonia two-photon laser-induced fluorescence for gas-phase diagnostics

Two-photon laser-induced fluorescence (LIF) of ammonia (NH3) with excitation of the C'-X transition at 304.8 nm and fluorescence detection in the 565 nm C'-A band has been investigated, targeting combustion diagnostics. The impact of laser irradiance, temperature, and pressure has been studied, and simulation of NH3-spectra, fitted to experimental data, facilitated interpretation of the results. T

Altered serotonin (5-HT) 1D and 2A receptor expression may contribute to defective insulin and glucagon secretion in human type 2 diabetes.

Islet produced 5-hydroxy tryptamine (5-HT) is suggested to regulate islet hormone secretion in a paracrine and autocrine manner in rodents. Hitherto, no studies demonstrate a role for this amine in human islet function, nor is it known if 5-HT signaling is involved in the development of beta cell dysfunction in type 2 diabetes (T2D). To clarify this, we performed a complete transcriptional mapping

Estrogen receptor alpha single nucleotide polymorphism as predictor of diabetes type 2 risk in hypogonadal men.

Abstract Estradiol (E2) is, apart from its role as a reproductive hormone, also important for cardiac function and bone maturation in both genders. It has also been shown to play a role in insulin production, energy expenditure and in inducing lipolysis. The aim of the study was to investigate if low circulating testosterone or E2 levels in combination with variants in the estrogen receptor alpha

Risk of familial classical Hodgkin lymphoma by relationship, histology, age, and sex: A joint study from five Nordic countries.

The rarity of familial Hodgkin lymphoma (HL) has hampered detailed analyses of familial clustering. We aimed to provide the familial risk of HL by relationship, histology, age at diagnosis and sex. A cohort of 57,475 first-degree relatives of 13,922 HL patients, diagnosed between 1955 and 2009, in five European countries was followed for HL incidence. Standardized incidence ratios (SIRs) were calc

MyD88 Signaling Regulates Steady-State Migration of Intestinal CD103+ Dendritic Cells Independently of TNF-α and the Gut Microbiota.

Intestinal homeostasis and induction of systemic tolerance to fed Ags (i.e., oral tolerance) rely on the steady-state migration of small intestinal lamina propria dendritic cells (DCs) into draining mesenteric lymph nodes (MLN). The majority of these migratory DCs express the α integrin chain CD103, and in this study we demonstrate that the steady-state mobilization of CD103(+) DCs into the MLN is