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Use of a resilient bond line to increase strength of long adhesive lap joints

The load capacity of long adhesive lap joints is often governed by stress concentrations at the lap ends. This paper investigates a method to minimize these stress concentrations by using a bond line with low shear stiffness and sufficient strength, here denoted as a resilient bond line. The resilient bond line is intended to increase the load carrying capacity of long lap joints by achieving a mo

Distribution of manufacturing strategy decision-making in multi-plant networks

This paper is concerned with the manufacturing strategy decision-making structure in multi-plant networks, i.e. how strategic manufacturing decision-making authority is distributed between the network level (i.e. headquarters) and the plant level. We use survey data from 107 manufacturing plants. This research identifies three different structures: centralised at the network headquarter, decentral

Assembling large genomes : Analysis of the stick insect (Clitarchus hookeri) genome reveals a high repeat content and sex-biased genes associated with reproduction

Background: Stick insects (Phasmatodea) have a high incidence of parthenogenesis and other alternative reproductive strategies, yet the genetic basis of reproduction is poorly understood. Phasmatodea includes nearly 3000 species, yet only the genome of Timema cristinae has been published to date. Clitarchus hookeri is a geographical parthenogenetic stick insect distributed across New Zealand. Sexu

Amyloid β42 peptide is toxic to non-neural cells in Drosophila yielding a characteristic metabolite profile and the effect can be suppressed by PI3K

The human Aβ42 peptide is associated with Alzheimer’s disease through its deleterious effects in neurons. Expressing the human peptide in adult Drosophila in a tissue- and time-controlled manner, we show that Aβ42 is also toxic in non-neural cells, neurosecretory and epithelial cell types in particular. This form of toxicity includes the aberrant signaling by Wingless morphogen leading to the even

InP/InAsP Nanowire-Based Spatially Separate Absorption and Multiplication Avalanche Photodetectors

Avalanche photodetectors (APDs) are key components in optical communication systems due to their increased photocurrent gain and short response time as compared to conventional photodetectors. A detector design where the multiplication region is implemented in a large band gap material is desired to avoid detrimental Zener tunneling leakage currents, a concern otherwise in smaller band gap materia

Transplantation of reprogrammed neurons for improved recovery after stroke

Somatic cells such as fibroblasts, reprogrammed to induced pluripotent stem cells, can be used to generate neural stem/progenitor cells or neuroblasts for transplantation. In this review, we summarize recent studies demonstrating that when grafted intracerebrally in animal models of stroke, reprogrammed neurons improve function, probably by several different mechanisms, e.g., trophic actions, modu

Early career researchers want Open Science

Open Science is encouraged by the European Union and many other political and scientific institutions. However, scientific practice is proving slow to change. We propose, as early career researchers, that it is our task to change scientific research into open scientific research and commit to Open Science principles.

How Many Conformations Need to Be Sampled to Obtain Converged QM/MM Energies? the Curse of Exponential Averaging

Combined quantum mechanical and molecular mechanical (QM/MM) calculations is a popular approach to study enzymatic reactions. They are often based on a set of minimized structures obtained on snapshots from a molecular dynamics simulation to include some dynamics of the enzyme. It has been much discussed how the individual energies should be combined to obtain a final estimate of the energy, but t

In Silico Synthesis of Microgel Particles

Microgels are colloidal-scale particles individually made of cross-linked polymer networks that can swell and deswell in response to external stimuli, such as changes to temperature or pH. Despite a large amount of experimental activities on microgels, a proper theoretical description based on individual particle properties is still missing due to the complexity of the particles. To go one step fu

Combined genome and transcriptome sequencing to investigate the plant cell wall degrading enzyme system in the thermophilic fungus Malbranchea cinnamomea

Background: Genome and transcriptome sequencing has greatly facilitated the understanding of biomass-degrading mechanisms in a number of fungal species. The information obtained enables the investigation and discovery of genes encoding proteins involved in plant cell wall degradation, which are crucial for saccharification of lignocellulosic biomass in second-generation biorefinery applications. T

Fundamental bounds on MIMO antennas

Antenna current optimization is often used to analyze the optimal performance of antennas. Antenna performance can be quantified in <i>e.g.</i>, minimum Q-factor and radiation efficiency. The performance of MIMO antennas is more involved and, in general, a single parameter is not sufficient to quantify it. Here, the capacity of an idealized channel is used as th

De novo transcriptome analysis of the common New Zealand stick insect clitarchus hookeri (Phasmatodea) Reveals genes involved in olfaction, digestion and sexual reproduction

Phasmatodea, more commonly known as stick insects, have been poorly studied at the molecular level for several key traits, such as components of the sensory system and regulators of reproduction and development, impeding a deeper understanding of their functional biology. Here, we employ de novo transcriptome analysis to identify genes with primary functions related to female odour reception, dige

Search for heavy resonances decaying to a W or Z boson and a Higgs boson in the qq¯(′)bb¯ final state in pp collisions at s=13 TeV with the ATLAS detector

A search for heavy resonances decaying to a W or Z boson and a Higgs boson in the qq¯(′)bb¯ final state is described. The search uses 36.1 fb−1 of proton–proton collision data at s=13 TeV collected by the ATLAS detector at the CERN Large Hadron Collider in 2015 and 2016. The data are in agreement with the Standard Model expectations, with the largest excess found at a resonance mass of 3.0 TeV wit

Positive selection and comparative molecular evolution of reproductive proteins from New Zealand tree weta (Orthoptera, Hemideina)

Animal reproductive proteins, especially those in the seminal fluid, have been shown to have higher levels of divergence than non-reproductive proteins and are often evolving adaptively. Seminal fluid proteins have been implicated in the formation of reproductive barriers between diverging lineages, and hence represent interesting candidates underlying speciation. RNA-seq was used to generate the

Search for Heavy Higgs Bosons A /H Decaying to a Top Quark Pair in pp Collisions at s =8 TeV with the ATLAS Detector

A search for heavy pseudoscalar (A) and scalar (H) Higgs bosons decaying into a top quark pair (tt) has been performed with 20.3 fb-1 of proton-proton collision data collected by the ATLAS experiment at the Large Hadron Collider at a center-of-mass energy s=8 TeV. Interference effects between the signal process and standard model tt production, which are expected to distort the signal shape from a

Assessing tools and implementation of the campaign “Making Cities Resilient”. Summary of briefing on two master’s theses conducted at Lund University, Sweden

This paper is a condensed version of a presentation held for the Advocacy and Outreach Section of the UNISDR on the 15th of November 2013. It draws upon findings and recommendations stemming from two master’s theses conducted at Lund University Centre for Risk Assessment and Management, LUCRAM (Karlsson & Nielsen, 2012; Lundby & Sjöberg, 2013). The presenter and author of the paper is a Ph

Fetal overgrowth in women with type 1 and type 2 diabetes mellitus

Objectives: Despite improved glycemic control, the rate of large-for-gestational-age (LGA) infants remains high in pregnancies complicated by diabetes mellitus type 1 (T1DM) and type 2 (T2DM). Poor glycemic control, obesity, and excessive gestational weight gain are the main risk factors. The aim of this study was to determine the relative contribution of these risk factors for LGA in women with T